Table 2, Statistics over 42 structurefunction classes
This table shows various totals from Figure 2 distributed among the 42 structurefunction classes  i.e. the seven functional categories in Table 1A multiplied by the six structural categories in Table 1B. Part A shows how many potential foldfunction combinations there are in Figure 2 amongst each of the 42 classes. Part B shows how many of these 21068 possible combinations are actually observed. Part C shows the total number of different folds (i.e. selected columns in figure 1) in each class. Part D shows the total number of different functions (i.e. selected rows in Figure 2) in each class. Part E shows the total number of matching Swissprot proteins in the 42 classes. Note that to observe a foldfunction combination one only needs the existence of a single match between a Swissprot protein and a SCOP domain. However, there can be many more. That is why the totals in table sum up to so much larger an amount than 331.
Here is an example of how to read the table, focussing on the allalpha, oxidoreductase region. Part A shows that there are 1104 cells, filled or unfilled, in this region, corresponding to possible combinations. Part B shows that 13 of these 1104 cells are filled, corresponding to observed allalpha, oxidoreductase combinations. Part C shows that there are 7 folds, corresponding to columns with filled cells in this region. Part D shows that there are 8 functions, corresponding to rows with filled cells in this region. Finally, in Part E we find that there are 150 Swissprot entries that have matches with a SCOP domain. They correspond to the 13 observed combinations in Part B.
A. Number of possible combinations between folds and functions in each of 42 classes (number of cells in Figure 2)

A 
B 
A/B 
A+B 
MULTI 
SML 
sum 
NONENZ 
46 
36 
48 
56 
15 
28 
229 
OX 
1104 
864 
1152 
1344 
360 
672 
5496 
TRAN 
598 
468 
624 
728 
195 
364 
2977 
HYD 
1334 
1044 
1392 
1624 
435 
812 
6641 
LY 
414 
324 
432 
504 
135 
252 
2061 
ISO 
460 
360 
480 
560 
150 
280 
2290 
LIG 
276 
216 
288 
336 
90 
168 
1374 
sum 
4232 
3312 
4416 
5152 
1380 
2576 
21068 
B. Number of observed combinations between folds and functions in each of 42 classes (number of filled cells in Figure 2)

A 
B 
A/B 
A+B 
MULTI 
SML 
sum 
NONENZ 
34 
30 
14 
28 
4 
26 
136 
OX 
13 
5 
17 
3 
4 
5 
47 
TRAN 
3 
3 
16 
8 
5 

35 
HYD 
4 
11 
30 
18 
4 

67 
LY 
2 
3 
13 
5 


23 
ISO 
1 
2 
7 
4 
2 

16 
LIG 

1 
2 
3 
1 

7 
sum 
57 
55 
99 
69 
20 
31 
331 
C. Number of folds in each of the 42 classes (columns with a filled cell in Figure 2)

A 
B 
A/B 
A+B 
MULTI 
SML 
sum 
NONENZ 
34 
30 
14 
28 
4 
26 
136 
OX 
7 
5 
9 
3 
3 
3 
30 
TRAN 
3 
2 
15 
6 
5 

31 
HYD 
4 
8 
19 
18 
3 

52 
LY 
2 
3 
8 
5 


18 
ISO 
1 
2 
7 
4 
2 

16 
LIG 

1 
1 
3 
1 

6 
sum 
51 
51 
73 
67 
18 
29 
289 
D. Number of functions in each of the 42 classes (rows with a filled cell in Figure 2)

A 
B 
A/B 
A+B 
MULTI 
SML 
sum 
NONENZ 
1 
1 
1 
1 
1 
1 
6 
OX 
8 
5 
9 
3 
3 
5 
33 
TRAN 
2 
3 
13 
8 
4 

30 
HYD 
4 
7 
19 
14 
4 

48 
LY 
2 
2 
7 
3 


14 
ISO 
1 
2 
5 
4 
1 

13 
LIG 

1 
2 
2 
1 

6 
sum 
18 
21 
56 
35 
14 
6 
150 
E. Total number of matching Swissprot sequences in each of the 42 foldfunction classes

A 
B 
A/B 
A+B 
MULTI 
SML 
sum 
NONENZ 
1940 
1159 
560 
638 
106 
892 
5295 
OX 
150 
202 
388 
50 
68 
18 
876 
TRAN 
65 
14 
363 
116 
174 

732 
HYD 
116 
394 
295 
452 
92 

1349 
LY 
40 
47 
168 
104 


359 
ISO 
2 
54 
122 
22 
2 

202 
LIG 

5 
26 
69 
24 

124 
sum 
2313 
1875 
1922 
1451 
466 
910 
8937 
© 1998 Hedi Hegyi & Mark Gerstein
© 1998 Graphics  Jimmy Lin
