This table shows various totals from Figure 2 distributed among the 42 structure-function classes -- i.e. the seven functional categories in Table 1A multiplied by the six structural categories in Table 1B. Part A shows how many potential fold-function combinations there are in Figure 2 amongst each of the 42 classes. Part B shows how many of these 21068 possible combinations are actually observed. Part C shows the total number of different folds (i.e. selected columns in figure 1) in each class. Part D shows the total number of different functions (i.e. selected rows in Figure 2) in each class. Part E shows the total number of matching Swissprot proteins in the 42 classes. Note that to observe a fold-function combination one only needs the existence of a single match between a Swissprot protein and a SCOP domain. However, there can be many more. That is why the totals in table sum up to so much larger an amount than 331.

Here is an example of how to read the table, focussing on the all-alpha, oxidoreductase region. Part A shows that there are 1104 cells, filled or unfilled, in this region, corresponding to possible combinations. Part B shows that 13 of these 1104 cells are filled, corresponding to observed all-alpha, oxidoreductase combinations. Part C shows that there are 7 folds, corresponding to columns with filled cells in this region. Part D shows that there are 8 functions, corresponding to rows with filled cells in this region. Finally, in Part E we find that there are 150 Swissprot entries that have matches with a SCOP domain. They correspond to the 13 observed combinations in Part B.