Advanced Biochemistry
Fall 1998
MB&B 400a/700a


Instructors:
Lynne Regan (in charge) Bass 232, 432-9843, lynne@nero.csb.yale.edu
Donald Engelman, Bass 420a, 432-5601, donald.engelman@yale.edu
Mark Gerstein, Bass 432a, 432-6105, mark.gerstein@yale.edu

Teaching Assistant:
Jennifer Larson, Bass 313, 432-5563,  jennifer.larson@yale.edu

Class location and time:
Bass 405, Tuesday/Thursday 9:00-10:15am

Discussion session:
To be announced

Requirements:
Undergraduates should have taken Organic Chemistry (Chem 125, 220 0r 225), Physical Chemistry (Chem 130) and Biochemistry (MB&B 300a/301b)

Problem sets:
Weekly, in general handed out on Thursday and handed in the following Thursday.

Credit/Fail option: Not available

Texts: There is no required text for the course. Copies of recent reviews and primary papers will be distributed in class. For a reference sources we recommend:
Biophysical Chemistry, Volumes I, II, III. C. Cantor and P. Schimmel (Freeman, NY 1980)
Enzyme Structure and Mechanism, A. Fersht (Freeman, NY 1985)
Proteins, T. Creighton (Freeman, NY 1993)
Dynamics of Proteins and Nucleic Acids, J. A. McCammon and S. C. Harvey (Cambridge, 1988)

Schedule and Topics
Problem sets
Selected Lectures Available On-line