BIOINFORMATICS Introduction

Bioinformatics

What is Bioinformatics?

Molecular Biology: an Information Science

Molecular Biology Information - DNA

Molecular Biology Information: Protein Sequence

Molecular Biology Information: Macromolecular Structure

Molecular Biology Information: Protein Structure Details

PPT Slide

Molecular Biology Information: Whole Genomes

Gene Expression Datasets: the Transcriptosome

Array Data

Other Whole-Genome Experiments

Molecular Biology Information: Other Integrative Data

Explonential Growth of Data Matched by Development of Computer Technology

Bioinformatics is born!

Weber Cartoon

The Character of Molecular Biology Information: Redundancy and Multiplicity

New Paradigm for Scientific Computing

General Types of ďInformaticsĒ in Bioinformatics

Bioinformatics Topics -- Genome Sequence

Bioinformatics Topics -- Protein Sequence

Bioinformatics Topics -- Sequence / Structure

Topics -- Structures

Topics -- Databases

Topics -- Genomics

Topics -- Simulation

Bioinformatics Schematic

Background

Are They or Arenít They Bioinformatics? (#1)

Are They or Arenít They Bioinformatics? (#1, Answers)

Are They or Arenít They Bioinformatics? (#2)

Are They or Arenít They Bioinformatics? (#2, Answers)

Are They or Arenít They Bioinformatics? (#3)

Are They or Arenít They Bioinformatics? (#3, Answers)

Major Application I: Designing Drugs

Major Application II: Finding Homologues

Major Application II: Finding Homologues (cont.)

Major Application I|I: Overall Genome Characterization

Simplfying Genomes with Folds, Pathways, &c

At What Structural Resolution Are Organisms Different?