## 01
Talk Overview

- Surface Area
- Why calculate?
- Types: A.S., M.S., H.S.
- How calculate A.S.

- Volume
- Why calculate?
- Voronoi construction for calculating volumes
- How to do this?
- Problems applying it to proteins
- Richards' solution
- Problems with his solution and ways of dealing with this

- Important Themes
- Nitty gritty of how to do calculations in 3D. How to calculate with
planes, lines, and so forth. This is generally useful.
- Case study of issues in taking off-shelf mathematical methods and
applying them to proteins.

###### Talk on Surfaces and Volumes /
(C) Mark Gerstein (mbg@hyper.stanford.edu) /
May 1996