8 amtk-qv-eb----------- [J] COG1514 2'-5' RNA ligase and related enzymes 18 ----y-v-ebr-uj-p----x [J] COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins 26 amtkyqvcebrhujgpolinx [J] COG0013 Alanyl-tRNA synthetase 4 amtk----------------- [J] COG1603 Archaeal homologs of ribonuclease P subunit Rpp30 22 amtkyqvcebrhujgpolinx [J] COG0018 Arginyl-tRNA synthetase 17 ----yqvcebrhujgpolinx [J] COG0173 Aspartyl-tRNA synthetase 17 amtky--ceb-h--gpol--- [J] COG0017 Aspartyl/asparaginyl-tRNA synthetases 20 a--kyqvcebrhujgpolinx [J] COG0215 Cysteinyl-tRNA synthetase 6 amtky---------------- [J] COG1899 Deoxyhypusine synthase 22 amtkyqvcebrhujgpolinx [J] COG0030 Dimethyladenosine transferase (rRNA methylation) 5 amtky---------------- [J] COG1798 Diphthamide biosynthesis methyltransferase DPH5 6 amtky---------------- [J] COG1736 Diphthamide synthase subunit DPH2 5 amtky---------------- [J] COG1976 Eukaryotic translation initiation factor 6 (EIF6) 5 amtky---------------- [J] COG1889 Fibrillarin-like rRNA methylase 43 amtkyqvcebrhujgpolinx [JE] COG0050 GTPases - translation elongation factors and sulfate adenylate transferase subunit 1 27 amt-yqvc-br-ujgpolinx [J] COG0154 Glu-tRNAGln amidotransferase A subunit (amidase) 22 amtkyqvc-br-ujgpolinx [J] COG0064 Glu-tRNAGln amidotransferase B subunit (PET112 homolog) 17 amt--qvc-br-ujgpolinx [J] COG0721 Glu-tRNAGln amidotransferase C subunit 30 amtkyqvcebrhujgpolinx [J] COG0008 Glutamyl- and glutaminyl-tRNA synthetases 11 -----qvceb-huj----inx [J] COG0752 Glycyl-tRNA synthetase, alpha subunit 11 -----qvceb-huj----inx [J] COG0751 Glycyl-tRNA synthetase, beta subunit 11 amtky-----r---gpol--- [J] COG0423 Glycyl-tRNA synthetase, class II 26 amtkyqvcebrhujgpolinx [J] COG0124 Histidyl-tRNA synthetase 22 amtkyqvcebrhujgpolinx [J] COG0060 Isoleucyl-tRNA synthetase 23 amtkyqvcebrhujgpolinx [J] COG0495 Leucyl-tRNA synthetase 7 amtk------------ol--x [J] COG1384 Lysyl-tRNA synthetase class I 21 ----yqvcebrhujgp-lin- [J] COG1190 Lysyl-tRNA synthetases 26 amtkyqvcebrhujgpolinx [J] COG0024 Methionine aminopeptidase 20 ----yqvcebrhujgpolinx [J] COG0223 Methionyl-tRNA formyltransferase 22 amtkyqvcebrhujgpolinx [J] COG0143 Methionyl-tRNA synthetase 17 -----qvcebrhujgpolinx [J] COG0242 N-formylmethionyl-tRNA deformylase 6 amtkyq--------------- [J] COG1867 N2,N2-dimethylguanosine tRNA methyltransferase 4 amtk----------------- [J] COG2016 PUA domain (predicted RNA-binding domain) 6 amtkyq--------------- [J] COG1503 Peptide chain release factor eRF, subunit 1 17 ----yqvcebrhujgpolinx [J] COG0193 Peptidyl-tRNA hydrolase 22 amtkyqvcebrhujgpolinx [J] COG0016 Phenylalanyl-tRNA synthetase alpha subunit 3 amt------------------ [J] COG2024 Phenylalanyl-tRNA synthetase alpha subunit, archaeal type 22 amtkyqvcebrhujgpolinx [J] COG0072 Phenylalanyl-tRNA synthetase beta subunit 14 -----qvcebrhuj--olinx [J] COG1185 Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase) 4 a-tky---------------- [J] COG1097 Predicted RNA-binding proteins (S1 domain) 3 a-tk----------------- [J] COG1096 Predicted RNA-binding proteins (consist of S1 domain and C4 Zn-finger domain) 6 amtky---------------- [J] COG1094 Predicted RNA-binding proteins (consist of S1 domain and KH domain) 4 amtk----------------- [J] COG1370 Predicted RNA-binding proteins (contain PUA domain) 4 amtk----------------- [J] COG1258 Predicted pseudouridylate synthase 23 -----qvcebrhuj--olinx [J] COG1187 Predicted pseudouridylate synthase family 1 44 ----yqvcebrhujgpolinx [J] COG0564 Predicted pseudouridylate synthase family 2 21 am-ky-vcebrh------in- [J] COG0144 Predicted rRNA methylase 9 -------cebrh--gp--in- [J] COG0219 Predicted rRNA methylase (SpoU class) 10 a----qvc-br-uj--o---x [J] COG1189 Predicted rRNA methylases 6 ------v-eb-huj------- [J] COG1188 Predicted small RNA-binding protein (S4 paralog) 22 amtkyqvcebrhujgpolinx [J] COG0442 Prolyl-tRNA synthetase 20 ----yqvcebrhujgpolinx [J] COG0216 Protein chain release factor A 14 -----qvcebrhuj--olinx [J] COG1186 Protein chain release factor B 7 amtky---------------- [J] COG1498 Protein implicated in ribosomal biogenesis, Nop56p homolog 4 am-ky---------------- [J] COG1374 Protein involved in ribosomal biogenesis, contains PUA domain 18 amtkyqvcebrh----olinx [J] COG0130 Pseudouridine synthase 23 amtkyqvcebrhujgpolinx [J] COG0101 Pseudouridylate synthase (tRNA psi55) 21 amtkyqvcebrh----olinx [J] COG0009 Putative translation factor (SUA5) 20 ---kyqvcebrhuj------- [J] COG0251 Putative translation initiation inhibitor 4 amtk----------------- [J] COG1549 Queuine tRNA-ribosyltransferases, contain PUA domain 18 amtk-qvceb-huj--o-inx [J] COG0343 Queuine/archaeosine tRNA-ribosyltransferase 12 a-tkyq--ebrh--------x [J] COG0689 RNase PH 7 ----y--ce-rh--------x [J] COG0349 Ribonuclease D 12 ---k-qvce-rh------inx [J] COG1530 Ribonucleases G and E 12 amtky-v--b----------- [J] COG1358 Ribosomal protein HS6-type (S12/L30/L7a) 23 amtkyqvcebrhujgpolinx [J] COG0081 Ribosomal protein L1 23 amtkyqvcebrhujgpolinx [J] COG0244 Ribosomal protein L10 23 amtkyqvcebrhujgpolinx [J] COG0080 Ribosomal protein L11 8 -----qvceb-huj------- [J] COG2264 Ribosomal protein L11 methylase 7 amtky---------------- [J] COG2058 Ribosomal protein L12E 23 amtkyqvcebrhujgpolinx [J] COG0102 Ribosomal protein L13 23 amtkyqvcebrhujgpolinx [J] COG0093 Ribosomal protein L14 4 -mt-y---------------- [J] COG2163 Ribosomal protein L14E 22 amtkyqvcebrhujgpolinx [J] COG0200 Ribosomal protein L15 6 amtky---------------- [J] COG1632 Ribosomal protein L15E 22 amtkyqvcebrhujgpolinx [J] COG0197 Ribosomal protein L16/L10E 17 ----yqvcebrhujgpolinx [J] COG0203 Ribosomal protein L17 21 amtkyqvcebrhujgpolinx [J] COG0256 Ribosomal protein L18 6 amtky---------------- [J] COG1727 Ribosomal protein L18E 17 ----yqvcebrhujgpolinx [J] COG0335 Ribosomal protein L19 5 amtky---------------- [J] COG2147 Ribosomal protein L19E 22 amtkyqvcebrhujgpolinx [J] COG0090 Ribosomal protein L2 16 -----qvcebrhujgpolinx [J] COG0292 Ribosomal protein L20 16 -----qvcebrhujgpolinx [J] COG0261 Ribosomal protein L21 6 amtky---------------- [J] COG2139 Ribosomal protein L21E 22 amtkyqvcebrhujgpolinx [J] COG0091 Ribosomal protein L22 21 amtkyqvcebrhujgpolinx [J] COG0089 Ribosomal protein L23 22 amtkyqvcebrhujgpolinx [J] COG0198 Ribosomal protein L24 7 amtky---------------- [J] COG2075 Ribosomal protein L24E 14 -----qvcebrhuj--olinx [J] COG1825 Ribosomal protein L25 (general stress protein Ctc) 17 ----yqvcebrhujgpolinx [J] COG0211 Ribosomal protein L27 18 ----yqvcebrhujgpolinx [J] COG0227 Ribosomal protein L28 22 amtkyqvcebrhujgpolinx [J] COG0255 Ribosomal protein L29 22 amtkyqvcebrhujgpolinx [J] COG0087 Ribosomal protein L3 17 amtkyqv-ebrh----ol--x [J] COG1841 Ribosomal protein L30/L7E 5 amtky---------------- [J] COG1911 Ribosomal protein L30E 18 -----qvcebrhujgpolinx [J] COG0254 Ribosomal protein L31 6 amtky---------------- [J] COG2097 Ribosomal protein L31E 16 ----yqvceb-hujgpolinx [J] COG0333 Ribosomal protein L32 5 amtky---------------- [J] COG1717 Ribosomal protein L32E 18 ----yqvcebrhujgpolinx [J] COG0267 Ribosomal protein L33 17 ----yqvcebrhujgpolinx [J] COG0230 Ribosomal protein L34 5 -mtky---------------- [J] COG2174 Ribosomal protein L34E 17 ----yqvcebrhujgpolinx [J] COG0291 Ribosomal protein L35 17 ----yqvcebrhujgpolinx [J] COG0257 Ribosomal protein L36 5 amtky---------------- [J] COG1997 Ribosomal protein L37AE 6 amtky---------------- [J] COG2126 Ribosomal protein L37E 5 amtky---------------- [J] COG2167 Ribosomal protein L39E 23 amtkyqvcebrhujgpolinx [J] COG0088 Ribosomal protein L4 6 amtky---------------- [J] COG1552 Ribosomal protein L40E 6 amtky---------------- [J] COG1631 Ribosomal protein L44E 23 amtkyqvcebrhujgpolinx [J] COG0094 Ribosomal protein L5 23 amtkyqvcebrhujgpolinx [J] COG0097 Ribosomal protein L6 18 ----yqvcebrhujgpolinx [J] COG0222 Ribosomal protein L7/L12 17 ----yqvcebrhujgpolinx [J] COG0359 Ribosomal protein L9 4 amtk----------------- [J] COG2157 Ribosomal protein LX (HL32) 17 ----yqvcebrhuj--olinx [J] COG0539 Ribosomal protein S1 14 ----yqvceb-h--gp----- [J] COG1098 Ribosomal protein S1 domains 22 amtkyqvcebrhujgpolinx [J] COG0051 Ribosomal protein S10 23 amtkyqvcebrhujgpolinx [J] COG0100 Ribosomal protein S11 24 amtkyqvcebrhujgpolinx [J] COG0048 Ribosomal protein S12 23 amtkyqvcebrhujgpolinx [J] COG0099 Ribosomal protein S13 25 amtkyqvcebrhujgpolinx [J] COG0199 Ribosomal protein S14 5 amtky---------------- [J] COG1439 Ribosomal protein S15A 23 amtkyqvcebrhujgpolinx [J] COG0184 Ribosomal protein S15P/S13E 17 ----yqvcebrhujgpolinx [J] COG0228 Ribosomal protein S16 23 amtkyqvcebrhujgpolinx [J] COG0186 Ribosomal protein S17 6 amtky---------------- [J] COG1383 Ribosomal protein S17E 18 ----yqvcebrhujgpolinx [J] COG0238 Ribosomal protein S18 22 amtkyqvcebrhujgpolinx [J] COG0185 Ribosomal protein S19 6 amtky---------------- [J] COG2238 Ribosomal protein S19E (S16A) 23 amtkyqvcebrhujgpolinx [J] COG0052 Ribosomal protein S2 16 -----qvcebrhujgpolinx [J] COG0268 Ribosomal protein S20 14 -----q-ceb-hujgpolinx [J] COG0828 Ribosomal protein S21 6 amtky---------------- [J] COG2004 Ribosomal protein S24E 5 amtky---------------- [J] COG1998 Ribosomal protein S27AE 6 amtky---------------- [J] COG2051 Ribosomal protein S27E 6 amtky---------------- [J] COG2053 Ribosomal protein S28E/S33 21 amtkyqvcebrhujgpolinx [J] COG0092 Ribosomal protein S3 6 amtky---------------- [J] COG1890 Ribosomal protein S3AE 24 amtkyqvcebrhujgpolinx [J] COG0522 Ribosomal protein S4 and related proteins 6 amtky---------------- [J] COG1471 Ribosomal protein S4E 22 amtkyqvcebrhujgpolinx [J] COG0098 Ribosomal protein S5 17 ----yqvcebrhujgpolinx [J] COG0360 Ribosomal protein S6 6 amtky---------------- [J] COG2125 Ribosomal protein S6E (S10) 23 amtkyqvcebrhujgpolinx [J] COG0049 Ribosomal protein S7 23 amtkyqvcebrhujgpolinx [J] COG0096 Ribosomal protein S8 7 amtky---------------- [J] COG2007 Ribosomal protein S8E 23 amtkyqvcebrhujgpolinx [J] COG0103 Ribosomal protein S9 17 ----yqvcebrhujgpolinx [J] COG0233 Ribosome recycling factor 16 -----qvcebrhujgpolinx [J] COG0858 Ribosome-binding factor A 12 -----qvcebrhuj--ol--x [J] COG0806 RimM protein, required for 16S rRNA processing 10 -----qvceb-huj--o---x [J] COG0809 S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase) 17 ---kyqvcebrh------in- [J] COG2265 SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase (trmA) 22 amtkyqvcebrhujgpolinx [J] COG0172 Seryl-tRNA synthetase 25 amtkyqvcebrhujgpolinx [J] COG0441 Threonyl-tRNA synthetase 35 amtkyqvcebrhujgpolinx [J] COG0480 Translation elongation and release factors (GTPases) 5 amtky---------------- [J] COG2092 Translation elongation factor EF-1beta 25 amtkyqvcebrhujgpolinx [J] COG0231 Translation elongation factor P/translation initiation factor eIF5-a 16 -----qvcebrhujgpolinx [J] COG0264 Translation elongation factor Ts 9 amtky--ce--h--------- [J] COG0023 Translation initiation factor (SUI1) 24 amtkyqvcebrhujgpolinx [J] COG0532 Translation initiation factor 2 (GTPase) 21 amtkyqvcebrhujgpolinx [J] COG0361 Translation initiation factor IF-1 16 -----qvcebrhujgpolinx [J] COG0290 Translation initiation factor IF3 6 amtky---------------- [J] COG1601 Translation initiation factor eIF-2, beta subunit/eIF-5 N-terminal domain 9 amtkyqvc-b----------- [J] COG0182 Translation initiation factor eIF-2B alpha subunit 8 am-ky-v-------------- [J] COG1184 Translation initiation factor eIF-2B delta subunit 5 amtky---------------- [J] COG1093 Translation initiation factor eIF2alpha 22 amtkyqvcebrhujgpolinx [J] COG0180 Tryptophanyl-tRNA synthetase 24 amtkyqvcebrhujgpolinx [J] COG0162 Tyrosyl-tRNA synthetase 21 amtkyqvcebrhujgpolinx [J] COG0525 Valyl-tRNA synthetase 7 amt----ce--h--------- [J] COG0565 rRNA methylase 30 a---yqvcebrhujgpolinx [J] COG0566 rRNA methylases 15 ----yqvcebrhuj--olinx [J] COG0324 tRNA delta(2)-isopentenylpyrophosphate transferase 4 amtk----------------- [J] COG1746 tRNA nucleotidyltransferase (CCA-adding enzyme) 22 ----yqvcebrhuj--olinx [J] COG0617 tRNA nucleotidyltransferase/poly(A) polymerase 6 amtky---------------- [J] COG1676 tRNA splicing endonuclease 16 -----qvcebrhujgpolinx [J] COG0336 tRNA-(guanine-N1)-methyltransferase 13 -----q-cebrhuj----inx [J] COG1295 tRNA-processing ribonuclease BN 46 ------vcebrh--------- [K] COG2207 AraC-type DNA-binding domain-containing proteins 3 a-------eb----------- [KH] COG1654 Biotin operon repressor 22 amtkyqvcebrhujgpolinx [K] COG0202 DNA-dependent RNA polymerase alpha subunit/40 kD subunit 26 amtkyqvcebrhujgpolinx [K] COG0085 DNA-dependent RNA polymerase beta subunit/140 kD subunit (split gene in Mjan, Mthe, Aful) 34 amtkyqvcebrhujgpolinx [K] COG0086 DNA-dependent RNA polymerase beta' subunit/160 kD subunit (split gene in Mjan, Mthe, Aful, Phor and Syn) 31 -----qvcebrhujgpolinx [K] COG0568 DNA-dependent RNA polymerase sigma subunits (sigma70/32) 3 amt------------------ [K] COG2093 DNA-dependent RNA polymerase subunit E'' 5 amtky---------------- [K] COG1996 DNA-dependent RNA polymerase subunit RPC10 (contains C4-type Zn-finger) 5 amtky---------------- [K] COG1644 DNA-dependent RNA polymerase, subunit N (RpoN/RPB10) 6 amtky---------------- [K] COG1095 DNA-directed RNA polymerase subunit E' 5 amtky---------------- [K] COG1919 DNA-directed RNA polymerase subunit K, RpoK/RPB6 8 amtky---------------- [K] COG1594 DNA-directed RNA polymerase subunit M/Transcription elongation factor TFIIS 5 amtky---------------- [K] COG2012 DNA-directed RNA polymerase, subunit H, RpoH/RPB5 6 amtky---------------- [K] COG1761 DNA-directed RNA polymerase, subunit L (RPC19) 6 amtky-v-------------- [K] COG1243 ELP3 component of the RNA polymerase II complex, consists of an N-terminal BioB/LipA-like domain and a C-terminal histone acetyltransferase domain (only BioB/LipA-like domain in Thermotoga) 19 ----yqvceb-hujgp-lin- [K] COG0557 Exoribonucleases 4 ------v-eb----------- [K] COG1954 Glycerol-3-phosphate responsive antiterminator (mRNA-binding) 5 amtky---------------- [K] COG1499 NMD protein affecting ribosome stability and mRNA decay 4 amtk----------------- [K] COG1813 Predicted transcription factor, homolog of eukaryotic MBF1 6 am-k-qv-------------- [K] COG1318 Predicted transcriptional regulators 6 -m-k-----b----------- [K] COG1510 Predicted transcriptional regulators 3 amt------------------ [K] COG1497 Predicted transcriptional regulators 5 ------vc-br---------- [K] COG1725 Predicted transcriptional regulators 4 a-tk----------------- [K] COG1777 Predicted transcriptional regulators 17 amt----cebr---------- [K] COG1733 Predicted transcriptional regulators 3 am-k----------------- [K] COG1709 Predicted transcriptional regulators 4 amtk----------------- [K] COG1395 Predicted transcriptional regulators 27 --t--qv-ebr---------x [K] COG1396 Predicted transcriptional regulators 18 amt--qvceb-h--------- [K] COG0425 Predicted transcriptional regulators 28 a----q-cebrhuj------- [K] COG0789 Predicted transcriptional regulators 19 amtk-q--ebr-uj--olinx [K] COG1475 Predicted transcriptional regulators 9 amtk-----b----------- [K] COG1378 Predicted transcriptional regulators 4 amt-------r---------- [K] COG1375 Predicted transcriptional regulators 5 amt------b----------- [K] COG1476 Predicted transcriptional regulators 41 amtk-qvcebr---------- [K] COG0640 Predicted transcriptional regulators 12 a-tk--v-ebr---------- [K] COG1695 Predicted transcriptional regulators 4 ---k--v-eb----------- [KT] COG1983 Putative stress-responsive transcriptional regulator PspC 10 ---ky----b-huj------- [K] COG0819 Putative transcription activator 9 -----qvc-br-uj--ol--- [K] COG1521 Putative transcriptional regulators, homologs of Bvg accessory factor 7 amtkyq--e------------ [K] COG0430 RNA phosphate cyclase 7 -----qv-ebrh--------x [K] COG1758 RNA polymerase-associated protein RpoZ, omega subunit 43 ----y--c----uj---l--- [K] COG0724 RNA-binding proteins (RRM domain) 7 a--------br---------- [K] COG2002 Regulators of stationary/sporulation gene expression 11 -----qvcebrh----o--nx [K] COG1544 Ribosome-associated protein Y (PSrp-1) 8 ------vcebrh--------- [KT] COG1974 SOS-response transcriptional repressors (LexA homologs, RecA-mediated autopeptidases) 9 -----q--eb--uj--olin- [K] COG1508 Sigma-54 (RpoN) and related alternative sigma subunuts 16 a-tky---------------- [K] COG1958 Small nuclear riboprotein (snRNP) homologs 15 -----qvcebr-uj---lin- [K] COG1191 Specialized DNA-dependent RNA polymerase sigma subunits including those involved in flagellar operon regulation 28 ------vcebrh-----l--- [K] COG1595 Specialized sigma subunits of RNA polymerase 32 a--ky-vcebrh--gp--in- [KL] COG0553 Superfamily II DNA/RNA helicases, SNF2 family 22 amtkyqvcebrhujgpolinx [K] COG0250 Transcription antiterminator NusG/RfaH 18 ------v-ebrhujgpolinx [K] COG0782 Transcription elongation factor 5 amtky---------------- [K] COG1308 Transcription factor homologous to NACalpha-BTF3 8 amtky---------------- [K] COG1405 Transcription initiation factor IIB 5 amtky---------------- [K] COG1675 Transcription initiation factor IIE, large subunit 5 amtky---------------- [K] COG2101 Transcription initiation factor TFIID (TATA-binding protein) 14 -----qvcebrhuj--olinx [K] COG0781 Transcription termination factor NusB 13 -----qv-ebrhuj--olinx [K] COG1158 Transcription termination factor rho 23 amtk-qvcebrhujgpolinx [K] COG0195 Transcription terminator NusA 14 --------ebr---------- [K] COG2188 Transcriptional regulators 15 ---ky-v-eb----------- [KE] COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs 28 a----qvcebrh----o---- [K] COG1940 Transcriptional regulators of NagC/XylR family 10 ------vc-br-ujgp--in- [K] COG1420 Transcriptional regulators of heat shock genes HrcA 20 ------v-eb-h--------- [KG] COG1349 Transcriptional regulators of sugar metabolism 38 ------v-ebrh--------- [K] COG1609 Transcriptional regulators of the LacI family 97 a-t--qvcebrh--------- [K] COG1309 Transcriptional regulators, AcrR family 15 --------ebrh--------- [K] COG2186 Transcriptional regulators, FadR family 9 ------v-ebr---------- [K] COG1802 Transcriptional regulators, GntR family 16 -----qv-ebrh--------- [K] COG1414 Transcriptional regulators, IclR family 47 amtk----ebrh--------- [K] COG1522 Transcriptional regulators, Lrp family 87 amt--q-cebrh--------- [K] COG0583 Transcriptional regulators, LysR family 12 ------vc-br-----ol--- [K] COG1316 Transcriptional regulators, LytR family 38 amtk--v-ebr---------- [K] COG1846 Transcriptional regulators, MarR/EmrR family 9 ------v-eb-h--------- [K] COG1737 Transcriptional regulators, RpiR family 6 -----q---br-----ol--x [K] COG1329 Transcriptional regulators, similar to M. xanthus CarD 19 ----yqvcebrhujgpolinx [K] COG0571 dsRNA-specific ribonuclease 5 ---------br-----o--nx [L] COG2094 3-methyladenine DNA glycosylase 31 amtkyqvcebrhujgpolinx [L] COG0258 5'-3' exonuclease (including N-terminal domain of PolI) 10 --t-----ebrhuj---lin- [L] COG1194 A/G-specific DNA glycosylase 13 amtkyq---br---------- [L] COG1793 ATP-dependent DNA ligase 12 -m--y---ebrh----o-in- [L] COG0507 ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member 11 --------ebrhuj--olinx [L] COG1074 ATP-dependent exoDNAse (exonuclease V), beta subunit, - helicase and exonuclease domains 13 amtkyqvceb------ol--- [L] COG0419 ATPase involved in DNA repair 53 amtkyqvcebrhujgpolinx [L] COG0470 ATPase involved in DNA replication 21 -----qvcebrhujgpolinx [L] COG0593 ATPase involved in DNA replication initiation 8 -------cebrh-----li-x [L] COG1195 ATPases involved in DNA repair 10 -----q-cebrhuj---l--x [L] COG0497 ATPases involved in DNA repair 10 a----------huj------- [L] COG2189 Adenine specific DNA methylase Mod 20 -m-k--v-e--huj------- [L] COG0863 Adenine-specific DNA methylase 17 -m-------brhuj-po---- [L] COG0827 Adenine-specific DNA methyltransferases 4 amtk----------------- [L] COG1107 Archaea-specific RecJ-like exonuclease, contains DnaJ-type Zn finger domain 4 amtk----------------- [L] COG2263 Archaeal N6-adenine DNA methylases 9 a-tky---------------- [LO] COG1474 Cdc6-related protein, AAA superfamily ATPase 28 a---yqvcebrhujgpolinx [L] COG0188 DNA gyrase (topoisomerase II) A subunit 28 a---yqvcebrhujgpolinx [L] COG0187 DNA gyrase (topoisomerase II) B subunit 4 a--ky---------------- [L] COG1224 DNA helicase TIP49, TBP-interacting protein 15 ----yqvceb-h----olinx [L] COG0323 DNA mismatch repair enzyme (predicted ATPase) 9 a--ky---e-r------l--- [L] COG1061 DNA or RNA helicases of superfamily II 15 ----yqvcebrhuj--olinx [L] COG0749 DNA polymerase I - 3'-5' exonuclease and polymerase domains 4 ------v--b----gp----- [L] COG2176 DNA polymerase III alpha subunit, the Gram-positive type 22 amtkyqvcebrhujgpolinx [L] COG0592 DNA polymerase III beta subunit 25 a---yqvcebrhuj---linx [L] COG0847 DNA polymerase III epsilon subunit (3'-5' exonuclease) 4 --t-yq---b----------- [L] COG1796 DNA polymerase IV (family X) 22 amtk-qvcebrhujgpolinx [L] COG0358 DNA primase (bacterial type) 6 amtky---------------- [L] COG1467 DNA primase, small subunit 14 amtkyqvcebr-----ol--- [L] COG0420 DNA repair exonuclease 9 -----qvceb-h--------- [L] COG2003 DNA repair proteins, RadC family 9 -----q--ebr---------- [L] COG1484 DNA replication protein DnaC 5 amtky---------------- [L] COG1697 DNA topoisomerase VI, subunit A 4 amtk----------------- [L] COG1389 DNA topoisomerase VI, subunit B 6 ------vcebrh--------- [L] COG1555 DNA uptake protein ComEA and related DNA-binding proteins 11 a-tky--cebr---------- [L] COG0122 DNA-3-methyladenine glycosidase II 19 -----qvcebrhujgpolinx [L] COG0587 DNA-dependent DNA polymerase III alpha chain 13 amtky---e------------ [L] COG0417 DNA-dependent DNA polymerase elongation subunit (family B) 6 a--k-qv-eb----------- [L] COG1515 Deoxyinosine 3'endonuclease (endonuclease V) 5 --t-y--ce------------ [L] COG0415 Deoxypyrimidine photolyase 6 amtky---------------- [L] COG1111 ERCC4-like helicases 8 amtky---------------- [L] COG1948 ERCC4-type nucleases 6 -mt--qv-----uj------- [L] COG2231 Endonuclease III related proteins 4 am---qv-------------- [L] COG1059 Endonuclease III-related proteins 13 -mtkyqv-ebr---gp--in- [L] COG0648 Endonuclease IV 5 amtky---------------- [L] COG2219 Eukaryotic-type DNA primase, large subunit 17 --t--qvcebrhujgpolinx [L] COG0178 Excinuclease ATPase subunit 14 a-t-y--cebrhuj--ol--x [L] COG0708 Exonuclease III 6 --------e-rh----o-in- [L] COG1330 Exonuclease V gamma subunit, RecC 6 ------v-ebrh--------x [L] COG1722 Exonuclease VII small subunit 11 ------v-ebrhuj----inx [L] COG1570 Exonuclease VII, large subunit 11 -------cebrh--gp----- [L] COG0266 Formamidopyrimidine-DNA glycosylase 18 --t--qvcebrhujgpolinx [L] COG0556 Helicase subunit of the DNA excision repair complex 15 ------vcebrhujgpolinx [L] COG2255 Helicase subunit of the Holliday junction resolvase (RuvB) 25 -----qvcebrhujgpolinx [L] COG0776 Histone-like DNA-binding protein 19 amtky---------------- [L] COG2036 Histones H3 and H4 15 ------vcebrhujgpolinx [L] COG0632 Holliday junction DNA helicase subunit 11 ------vce-rhuj---linx [L] COG0817 Holliday junction endodeoxyribonuclease RuvC 4 amtk----------------- [L] COG1591 Holliday junction resolvase - archaeal type 5 amtk-q--------------- [L] COG1423 Homologs of eukaryotic DNA ligase III 12 ----y---e--h----ol--- [L] COG1643 HrpA-like helicases 11 -----q-ce------------ [L] COG1662 Insertion element IS1 protein InsB, putative transposase 49 amtk-qvcebrhuj---linx [L] COG0582 Integrase 44 -m-kyqvc-br---------- [L] COG1372 Inteins 4 -------ce-r---------- [L] COG1403 McrA and related restriction endonucleases 8 --tk-q-ceb--uj------- [L] COG1401 McrB and related restriction endonucleases 20 amtkyqv-ebrhuj---lin- [L] COG0350 Methylated DNA-protein cysteine methyltransferase 11 -mtkyq---b-h--gp----- [L] COG1525 Micrococcal nuclease (thermonuclease) homologs 3 --t-----e-r---------- [L] COG1715 Mrr restriction endonuclease 9 --tk-qvc-b--uj--o---- [L] COG1193 MutS-like ATPases involved in mismatch repair, family 1 17 ----yqvceb-h----olinx [L] COG0249 MutS-like ATPases involved in mismatch repair, family 2 13 ------vcebrhuj--olinx [L] COG0742 N6-adenine-specific methylase 17 -----qvcebrhujgpolinx [L] COG0272 NAD-dependent DNA ligase (contains BRCT domain type II) 52 a-t-yqvcebrhuj---linx [LR] COG0494 NTP pyrophosphohydrolases (MutT family) including oxidative damage repair enzymes 5 amtk----------------- [L] COG1933 Novel archaeal DNA polymerase (contains Zn-fingers) 22 --t--qvcebrhujgpolinx [L] COG0322 Nuclease subunit of the excinuclease complex 14 ----y--cebr---gp----- [L] COG0389 Nucleotidyltransferase/DNA polymerase involved in DNA repair 15 amtky---------------- [L] COG1241 Predicted ATPase involved in replication control, Cdc46/Mcm family 5 amtky---------------- [L] COG1041 Predicted DNA modification methylase 4 amtk----------------- [L] COG1491 Predicted DNA-binding protein 21 amtkyqvcebrhuj--olinx [L] COG0177 Predicted EndoIII-related endonuclease 7 am-k---ceb-h--------- [L] COG0116 Predicted N6-adenine-specific DNA methylases 9 -----qvce-rhuj---l--- [L] COG0792 Predicted endonuclease distantly related to archaeal Holliday junction resolvase 4 ------vc----uj------- [L] COG1787 Predicted endonuclease distantly related to archaeal Holliday junction resolvase and Mrr-like restriction enzymes 14 -----qvcebrhujgp--inx [L] COG0816 Predicted endonuclease involved in recombination (possible Holliday junction resolvase in Mycoplasmas and B. subtilis) 26 amtk--vcebrh--------- [L] COG1082 Predicted endonucleases 5 a-tky---------------- [L] COG2123 Predicted nuclease related to RNase PH 5 amtky---------------- [L] COG1599 Predicted single-stranded DNA binding protein (homolog of replication factor A large subunit) 14 ------v-e--huj------- [L] COG1943 Predicted transposase 8 a-------e-r---------- [L] COG1425 Predicted transposase 35 -m-k-qvce-r-uj--o---- [L] COG0675 Predicted transposases 14 -----qvcebrhuj--olinx [L] COG1198 Primosomal protein N' (replication factor Y) - superfamily II helicase 5 amtky---------------- [L] COG1588 RNAse P subunit P29/POP4 15 ------vcebrhujgpolinx [L] COG0594 RNase P protein component 12 -mtkyq--ebrh--------- [L] COG1199 Rad3-related DNA helicases 29 amtkyqvcebrhujgpolinx [L] COG0468 RecA/RadA recombinase 12 -----qvcebrhuj--ol--x [LK] COG1200 RecG-like helicases 8 -------cebrh-----lin- [L] COG1381 Recombination protein RecO 12 -----q-cebrhuj---linx [L] COG0353 Recombinational DNA repair protein 20 -----qvcebrhujgpolinx [L] COG0305 Replicative DNA helicase 30 amt-----e-rhujgp----- [L] COG0732 Restriction endonuclease S subunits 15 amt-----e--huj-p----- [L] COG0610 Restriction enzymes type I helicase subunits and related helicases 8 am-k-qv-------------- [L] COG1110 Reverse gyrase 11 ----y--cebrhuj---l--x [L] COG0328 Ribonuclease HI 18 amtkyqvcebrhuj--o-inx [L] COG0164 Ribonuclease HII 6 -----q---b----gp--in- [L] COG1039 Ribonuclease HII Family 2 21 ----yqvcebrhujgpolinx [L] COG0629 Single-stranded DNA-binding protein 27 amtk-qvceb-huj--olinx [L] COG0608 Single-stranded DNA-specific exonuclease 9 -m-k---ce--huj---l--- [L] COG0338 Site-specific DNA methylase dam 15 -mtk---ceb-huj------- [L] COG0270 Site-specific DNA methylase dcm 7 ---k----ebr---------- [L] COG1961 Site-specific recombinases, DNA invertase Pin homologs 10 amtk-q---b----gpo---- [L] COG1658 Small primase-like proteins (Toprim domain) 5 amtky---------------- [L] COG1311 Small subunit of DNA polymerase, predicted phosphatase (SbcD-like family) 10 -------ceb-huj--ol--x [L] COG0783 Starvation-inducible DNA-binding protein Dps 36 --t-yqvcebrhujgpolinx [L] COG0210 Superfamily I DNA and RNA helicases 24 amtkyqvce-r-u-gp----- [L] COG1112 Superfamily I DNA helicases and helicase subunits 79 amtkyq-cebrhujgpol--x [LKJ] COG0513 Superfamily II DNA and RNA helicases 7 ----y--ceb-h-----l--- [L] COG0514 Superfamily II DNA helicases, RecQ family 27 amtkyqvcebrhujgpolinx [L] COG0550 Topoisomerase IA 13 ------vcebrhuj--olinx [LK] COG1197 Transcription-repair coupling factor - helicase of superfamily II 3 am-k----------------- [L] COG2178 Translin (RNA-binding protein, recombination hotspot binding in eukaryotes) 17 -mt-----e-rhuj-p----- [L] COG0286 Type I restriction-modification system methyltransferase subunit 6 -m-------b--uj--o---- [L] COG1002 Type II restriction enzyme, methylase subunits 8 ----y-v-ebrhuj------- [L] COG2256 Uncharacterized ATPase related to the helicase subunit of the Holliday junction resolvase 12 ----y---ebrhujgpo-in- [L] COG0692 Uracil DNA glycosylase 10 a--k-qvc--r-uj---l--x [L] COG1573 Uracil-DNA glycosylase 19 amtk--v-eb-hujgp-lin- [L] COG0551 Zn-finger domain associated with topoisomerase type I 5 amtky---------------- [L] COG2023 Zn-ribbon protein, RNAse P subunit RPR2 41 amtk-qvcebr-uj--ol--- [D] COG0455 ATPases involved in chromosome partitioning 35 -mtk-q-c-br-ujgpolinx [D] COG1192 ATPases involved in chromosome partitioning 23 amtkyqvcebrhuj------x [D] COG0489 ATPases involved in chromosome partitioning, mrp family 28 -----qvcebrhuj--olinx [D] COG0772 Bacterial cell division membrane protein FtsW/MrdB/SpoVE 4 -------ce---uj------- [D] COG0851 Bacterial cell division topological specificity factor MinE 7 -----qvceb--uj------- [D] COG0850 Bacterial septum site-determining protein MinC 26 amtk-qvcebrhujgpol--x [D] COG0206 Cell division GTPase FtsZ 4 --------ebrh--------- [D] COG2177 Cell division protein FtsX 18 am-kyqvc-br---gpol--- [D] COG1196 Chromosome segregation ATPases 22 --------ebrhuj--olinx [D] COG1674 DNA segregation ATPase FtsK/SpoIIIE and related proteins 5 --------e-rhuj------- [D] COG2184 Fic protein involved in cell division 25 a-t-yqv-eb-huj--olinx [D] COG1077 HSP70 class molecular chaperones involved in cell morphogenesis 15 -m-kyqvcebrhuj------- [D] COG0239 Integral membrane protein possibly involved in chromosome condensation 11 amt-y---e--h----ol--x [D] COG0293 Methyltranferase FtsJ involved in cell division 4 -----qvc-b----------- [D] COG1206 NAD(FAD)-utilizing enzyme apparently involved in cell division 16 ----yqvceb-hujgpolinx [D] COG0445 NAD/FAD-utilizing enzyme apparently involved in cell division 12 -----qvceb-huj--ol--x [D] COG0849 Predicted ATPases of the HSP70 class involved in cell division 14 ---kyqvcebr-uj----inx [D] COG0424 Putative inhibitor of septum formation 12 -------cebrhuj---l-n- [DR] COG1135 Uncharacterized ABC-type transport system ATPase component/cell division protein FtsE 30 amtky--c-br---------- [O] COG0464 AAA+ class ATPases 4 am---q--e------------ [O] COG1397 ADP-ribosylglycohydrolase 11 amtky---------------- [O] COG1222 ATP-dependent 26S proteasome regulatory subunit 16 ----yqv-eb-hujgpolinx [O] COG0466 ATP-dependent Lon protease, bacterial type 27 ----yqvcebrhujgpolinx [O] COG0465 ATP-dependent Zn proteases 15 ----yqvcebrhuj--olinx [O] COG1219 ATP-dependent protease Clp, ATPase subunit ClpX 9 -----qv-eb-huj--o---x [O] COG1220 ATP-dependent protease HslUV, ATPase subunit HslU/ClpY 4 ------v-e--h-----l--- [O] COG1068 ATP-dependent unnamed protease 34 --t-yqvcebrhujgpolinx [O] COG0542 ATPases with chaperone activity, ATP-binding domain 38 amtkyqvcebrhujgpolinx [O] COG0459 Chaperonin GroEL (HSP60 family) 17 ----yqvcebrhujgpolinx [O] COG0234 Co-chaperonin GroES (HSP10) 12 --t-y--cebrhujgp-l--- [O] COG0229 Conserved domain frequently associated with peptide methionine sulfoxide reductase 6 a-------e--h--------x [O] COG1138 Cytochrome c biogenesis factors, CcmF family 13 a-tk-qvc-brhuj---l--- [O] COG0785 Cytochrome c biogenesis protein 12 a----q-cebrhuj------x [O] COG0755 Cytochrome c-type biogenesis protein (heme exporter protein C) 9 --------eb-huj----inx [O] COG1495 Disulfide bond formation protein DsbB 9 ----y--ce--h--------x [O] COG1076 DnaJ-domain-containing proteins 1 9 ----y--c--r---------- [O] COG1928 Dolichyl-phosphate-mannose--protein O-mannosyl transferase PMT1 16 -----qvcebrhujgpolinx [O] COG0544 FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor) 11 ----y--ce--h-----lin- [O] COG0545 FKBP-type peptidyl-prolyl cis-trans isomerases 1 11 amtk----e--huj---l--- [O] COG1047 FKBP-type peptidyl-prolyl cis-trans isomerases 2 4 -----q--e-rh--------- [OT] COG1391 Glutamine synthetase adenylyltransferase GlnE 22 a-tky-vcebrh-----l--x [O] COG0695 Glutaredoxin and related proteins 7 ----y--ce--h--------x [O] COG0278 Glutaredoxin-related proteins 7 ----y--ceb----------- [O] COG0386 Glutathione peroxidase 12 ----y--ce--h--------x [O] COG0625 Glutathione-S-transferases 9 amt----ce--huj------- [O] COG0298 Hydrogenase expression factor 10 amtk-q-ce---uj------- [O] COG0409 Hydrogenase expression-formation factor 3 amt------------------ [O] COG1973 Hydrogenase expression/formation protein HypE 11 amtk-q-ce---uj------- [O] COG0309 Hydrogenase formation factor 9 amtk-q-ce---uj------- [O] COG0068 Hydrogenase maturation factor 13 ------vcebrh--gpolinx [O] COG1214 Inactive homologs of metal-dependent proteases, putative molecular chaperones 32 amtkyqvcebrhuj--ol--x [O] COG0330 Membrane protease subunits, stomatin/prohibitin homologs 23 amtkyqvcebrhujgpolinx [O] COG0533 Metal-dependent proteases with possible chaperone activity 19 amtkyqvcebr---------x [O] COG0071 Molecular chaperone (small heat shock protein) 18 --t-yqvcebrhujgpolinx [O] COG0576 Molecular chaperone GrpE (heat shock protein) 12 ----y--cebrhuj--ol--x [O] COG0326 Molecular chaperone, HSP90 family 44 --t-yqvcebrhujgpolinx [O] COG0443 Molecular chaperones (HSP70/DnaK family) 5 -------ce---uj--o---- [O] COG2214 Molecular chaperones, DnaJ class, CbpA family 52 --t-yqvcebrhujgpolinx [O] COG0484 Molecular chaperones, DnaJ family (contain C-terminal Zn finger domain) 21 -----qvceb-h-----l--- [O] COG1221 NtrC family transcriptional regulators, ATPase domain 17 amtk-q-ceb-huj------x [O] COG0602 Organic radical activating enzymes 23 ----yqvceb-huj--ol--x [O] COG0760 Parvulin-like peptidyl-prolyl isomerase 13 --t-y--cebrhujgp-l--- [O] COG0225 Peptide methionine sulfoxide reductase 21 --t-y--cebrhuj---l--- [O] COG0652 Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family 3 ----y--c---h--------- [O] COG0678 Peroxiredoxin 15 ----yqvcebrhuj------- [O] COG1225 Peroxiredoxins 14 -----qvcebrhuj---linx [O] COG1066 Predicted ATP-dependent serine protease (Sms family) 3 amt------------------ [O] COG1223 Predicted ATPases, AAA+ class 1 30 amtkyq-cebrhuj------- [O] COG0501 Predicted Zn-dependent proteases with possible chaperone function, HtpX family 4 -m-k---c------------- [O] COG2192 Predicted carbamoyl transferase, NodU family 5 ----y--ce------------ [O] COG0435 Predicted glutathione S-transferase 14 -mt--q--eb-huj------- [O] COG0826 Protease related to collagenase 22 -----qvcebrhuj--olinx [O] COG0740 Protease subunits of ATP-dependent proteases, ClpP family 33 amtkyqv-ebrhuj--o---x [O] COG0638 Proteasome protease subunit HslV 18 a----q-cebrhuj----inx [O] COG1651 Protein-disulfide isomerases DsbC/DsbG 9 a--ky--c--rh--------- [O] COG2020 Putative protein-S-isoprenylcysteine methyltransferase 3 ---k-----br---------- [O] COG2039 Pyrrolidone-carboxylate peptidase (N-terminal pyroglutamyl peptidase) 21 amtk-qv-e-rh--------- [O] COG1180 Pyruvate-formate lyase-activating enzyme 4 -----q-c-br---------- [O] COG1333 ResB protein required for cytochrome c biosynthesis 5 ----y---e---------in- [O] COG1025 Secreted/periplasmic Zn-dependent peptidases, insulinase-like 6 --------eb----gp----- [O] COG1764 Stress-induced protein OsmC 20 a---yq-c-br---------- [O] COG1404 Subtilisin-like serine proteases 23 amtkyqvcebr-uj---linx [O] COG0450 Thiol - alkyl hydroperoxide reductases 7 -----q--ebrhuj------- [O] COG2077 Thiol peroxidase 104 amtkyqvcebrhujgpolinx [OC] COG0526 Thiol-disulfide isomerase and thioredoxins 32 amtkyqvcebrhujgpolinx [O] COG0492 Thioredoxin reductase/alkyl hydroperoxide reductase 13 a---y--ceb-huj----inx [O] COG0694 Thioredoxin-like proteins and domains - NifU family 33 --t-yqvcebrhuj--olinx [O] COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain 7 amtk-----b----------- [O] COG1067 Uncharacterized ATP-dependent protease, related to Lon 6 ----yq-c-br---------x [O] COG1612 Uncharacterized protein required for cytochrome oxidase assembly 5 -------c--rhuj------- [O] COG0830 Urease accessory protein UreF 4 -------c---huj------- [O] COG0829 Urease accessory protein UreH 16 -----qvcebrhujgpolinx [O] COG0691 tmRNA-binding protein SmpB 8 -----q--e--huj----inx [M] COG1519 3-Deoxy-D-manno-octulosonic-acid transferase (LPS biosynthesis) 20 -----q-ce--huj------- [M] COG0859 ADP-heptose:LPS heptosyltransferase 9 -----q-ce--huj----inx [M] COG1043 Acyl-[acyl carrier protein]--UDP-N-acetylglucosamine O-acyltransferase 13 -----q-cebrhuj--ol--x [M] COG0787 Alanine racemase 16 -----qvce-rhuj--olinx [M] COG0815 Apolipoprotein N-acyltransferase 5 a--k----eb----------- [M] COG1794 Aspartate racemase 22 ---k---cebr---------x [M] COG1680 Beta-lactamase class C and other penicillin binding proteins 8 -----q--e--huj----inx [M] COG1212 CMP-2-keto-3-deoxyoctulosonic acid synthetase 3 -------c---hu-------- [M] COG1083 CMP-N-acetylneuraminic acid synthetase 32 -----qvcebrhuj--olinx [M] COG0768 Cell division protein FtsI/penicillin-binding protein 2 8 -------cebrh----ol--x [M] COG1589 Cell division septal protein FtsQ 23 -------cebrhuj----in- [M] COG0791 Cell wall-associated hydrolases (invasion-associated proteins) 14 -----q--e-r-uj------- [M] COG2230 Cyclopropane fatty acid synthase and related methyltransferases 15 -----qvcebrhuj--olinx [M] COG1181 D-alanine-D-alanine ligase and related ATP-grasp enzymes 5 -------c-b------ol--- [M] COG1876 D-alanyl-D-alanine carboxypeptidase 16 --------ebrh----olinx [M] COG1686 D-alanyl-D-alanine carboxypeptidase 7 -------cebrh--------- [M] COG2027 D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4) 3 -------ce-r---------- [M] COG2173 D-alanyl-D-alanine dipeptidase 7 ------vceb-huj------- [M] COG0818 Diacylglycerol kinase 12 -----qvcebrhuj---lin- [M] COG0821 Essential bacterial protein GcpE, involved in density-dependent regulation of peptidoglycan biosynthesis 11 amtky-vc-b--uj--o---- [M] COG1293 Fibronectin-binding protein (function unknown) 10 a-t--q-ce-r-uj------- [M] COG1089 GDP-D-mannose dehydratase 18 -mtkyqvcebrhuj---lin- [M] COG0449 Glucosamine-fructose-6-phosphate aminotransferase, contains aminotransferase and phosphosugar isomerase domains 11 -----q-cebrhuj--ol--- [M] COG0796 Glutamate racemase 109 amtkyqvcebrhuj--o---x [M] COG0438 Glycosyltransferases I 97 amtkyqvcebrhujgpo---x [M] COG0463 Glycosyltransferases involved in cell wall biogenesis 10 a-tk-q-ceb----------- [M] COG1215 Glycosyltransferases, probably involved in cell wall biogenesis 5 -------cebrh--------- [M] COG1970 Large-conductance mechanosensitive channel MscL 9 -----q-ce--huj----inx [M] COG0763 Lipid A disaccharide synthetase 15 --------eb-huj------x [M] COG1442 Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases 9 --------eb-huj---l-n- [M] COG1464 Lipoprotein, attached to the cytoplasmic membrane 11 -----q-ce--huj--ol--x [M] COG0797 Lipoproteins 8 a--k-qvce---uj------- [M] COG0836 Mannose-1-phosphate guanylyltransferase 23 -----qvcebrhuj--ol--x [M] COG0744 Membrane carboxypeptidase (penicillin-binding protein) 12 a----q-c-br-uj------x [M] COG1682 Membrane permeases involved in cell wall biosynthesis 46 -----qvcebrhuj--ol--x [M] COG0739 Membrane proteins related to metalloendopeptidases 10 -----qvcebrhuj------x [M] COG1207 N-acetylglucosamine-1-phosphate uridyltransferase (GlmU); Contains nucleotidyltransferase and I-patch acetyltransferase domains 22 -----q-cebrhuj--olin- [M] COG0860 N-acetylmuramoyl-L-alanine amidase 54 amtkyqvcebrhuj--o---- [MG] COG0451 Nucleoside-diphosphate-sugar epimerases 30 amtkyq-cebrh-----l--- [MJ] COG1208 Nucleoside-diphosphate-sugar pyrophosphorylases involved in lipopolysaccharide biosynthesis/translation and initiation factor eIF2B subunits 9 -----q--e--huj--ol--x [M] COG1452 Organic solvent tolerance protein OstA 13 -----qvcebrhuj---lin- [M] COG0761 Penicillin tolerance protein LytB 16 -----qvceb-huj--olinx [M] COG0793 Periplasmic protease 7 -----q--e--huj------- [M] COG0810 Periplasmic protein TonB, links inner and outer membranes 5 -----qvce------------ [M] COG1596 Periplasmic protein involved in polysaccharide export 10 ------v-eb-huj------- [M] COG1368 Phosphoglycerol transferase MdoB and related proteins, alkaline phosphatase superfamily 14 -----qvcebrhujgpol--x [M] COG0357 Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division 16 -----qvcebrhujgpolinx [M] COG0275 Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis 13 am---qvcebr---------x [M] COG1004 Predicted UDP-glucose 6-dehydrogenase 7 ----y----b-h--gp-l--- [M] COG0510 Predicted choline kinase involved in LPS biosynthesis 5 ----y----b--u----l--- [M] COG1696 Predicted membrane protein involved in D-alanine export 23 amtk-qvcebrhuj--olinx [M] COG0750 Predicted membrane-associated Zn-dependent proteases 1 9 -m----v--b--uj---l--x [MG] COG1086 Predicted nucleoside-diphosphate sugar epimerases 13 ----yq-ceb----------- [MG] COG0702 Predicted nucleoside-diphosphate-sugar epimerases 15 -----qvce--huj--olinx [M] COG0729 Predicted outer membrane protein 6 --tk--v-eb----------- [M] COG2222 Predicted phosphosugar isomerases 22 -mt--qvcebr-uj---l--- [M] COG0399 Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis 3 a--k-q--------------- [M] COG1213 Predicted sugar nucleotidyltransferases 16 amtk-q-ceb-huj----inx [M] COG0794 Predicted sugar phosphate aminotransferases involved in capsule formation 16 -----qvcebrhujgpolinx [M] COG0682 Prolipoprotein diacylglyceryltransferase 6 -m-k-----b----------- [M] COG2247 Putative cell wall-binding domain 7 --tk-----b----------- [M] COG1887 Putative glycosyl/glycerophosphate transferases involved in teichoic acid biosynthesis TagF/TagB/EpsJ/RodC 12 -----q--eb-huj--olinx [M] COG1792 Rod shape-determining protein MreC 5 -m-------b--uj---l--- [M] COG2089 Sialic acid synthase 27 -----qvceb-huj--ol--x [M] COG0741 Soluble lytic murein transglycosylase and related regulatory proteins 3 -------ceb----------- [M] COG1247 Sortase and related acyltransferases 3 -m-------b-------l--- [M] COG1861 Spore coat polysaccharide biosynthesis protein F (SpsF), CMP-KDO synthetase homolog 7 ------vceb-h--------- [M] COG2148 Sugar transferases involved in lipopolysaccharide synthesis 6 ------vceb-------l--- [M] COG1922 Teichoic acid biosynthesis proteins 9 -----q-ce--huj----inx [M] COG0774 UDP-3-0-acyl-N-acetylglucosamine deacetylase 9 -----q-ce--huj----inx [M] COG1044 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase 5 -mtk----e------------ [M] COG0677 UDP-N-acetyl-D-mannosaminuronate dehydrogenase 9 -mtk--vceb----------x [M] COG0381 UDP-N-acetylglucosamine 2-epimerase 15 -----qvcebrhuj--olinx [M] COG0766 UDP-N-acetylglucosamine enolpyruvyl transferase 15 -----qvcebrhuj--olinx [M] COG0812 UDP-N-acetylmuramate dehydrogenase 16 -----qvcebrhuj--olinx [M] COG0773 UDP-N-acetylmuramate-alanine ligase 16 --t--qvcebrhuj--olinx [M] COG0771 UDP-N-acetylmuramoylalanine-D-glutamate ligase 30 -mtkyqvcebrhuj--olinx [M] COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase 16 -mt--qvcebrhuj--olinx [M] COG0770 UDP-N-acetylmuramyl pentapeptide synthase 19 --t--qvcebrhuj--olinx [M] COG0769 UDP-N-acetylmuramyl tripeptide synthase 5 --t-----e-r---gp----- [M] COG0562 UDP-galactopyranose mutase 13 --t-yq-ceb-hujgp----- [M] COG1087 UDP-glucose 4-epimerase 16 -mt--q--ebrhujgpo---- [M] COG1210 UDP-glucose pyrophosphorylase 16 -----qvcebrhuj--olinx [M] COG0707 UDP-glucuronosyltransferases 3 -----q-ce------------ [M] COG1462 Uncharacterized protein CsgG involved in formation of curli polymers 3 a--------b------o---- [M] COG2088 Uncharacterized protein SpoVG, involved in the regulation of septum location 10 ---k-q-ceb----------- [M] COG1807 Uncharacterized protein, affecting LPS biosynthesis 9 --tk---cebr---------- [M] COG1898 dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes 8 --tk-q-cebr---------x [M] COG1091 dTDP-4-dehydrorhamnose reductase 9 a-tk---cebrh--------- [M] COG1088 dTDP-D-glucose 4,6-dehydratase 9 a-tk--vcebr---------- [M] COG1209 dTDP-glucose pyrophosphorylase 10 am-k----------------- [N] COG1681 Archaeal flagellins 19 -----q-ce--huj----inx [N] COG0848 Biopolymer transport protein ExbD 19 --t--q-ce--huj----inx [N] COG0811 Biopolymer transport proteins 9 a--k--v--b--uj---l--- [NT] COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation 5 a--k--v--b------o---- [NT] COG1871 Chemotaxis protein CheD; stimulates methylation of MCP proteins 15 a--k--vceb--uj--ol--- [N] COG0643 Chemotaxis protein histidine kinase and related kinases 8 a--k--v-eb------ol--- [NT] COG2201 Chemotaxis response regulator CheB, consists of CheY-like receiver domain and a methylesterase (demethylase) domain 23 a--k--vceb--uj--ol--- [N] COG0835 Chemotaxis signal transduction protein CheW 7 --------ebrh-----l--- [N] COG1292 Choline-glycine betaine transporter 19 a----q-cebrhuj------x [N] COG1826 Component of Sec-independent protein secretion pathway TatA (homolog of Tha4/Hcf106) 12 -----qv-eb--uj--olin- [N] COG1157 Flagellar ATPase-like component 7 -----qv--b--uj--ol--- [N] COG1419 Flagellar GTP-binding protein FlhF 9 ------v-eb--uj--olin- [N] COG1317 Flagellar assembly protein FliH 5 -----qv-e---uj------- [N] COG2063 Flagellar basal body L-ring protein FlgH 10 -----qv-eb--uj--olin- [N] COG1766 Flagellar basal body M-ring protein FliF 25 -----qv-eb--uj--ol--- [N] COG1749 Flagellar basal body and hook proteins 8 -----qv-eb--uj--ol--- [N] COG1815 Flagellar basal body protein FlgB 8 -----qv-eb--uj--ol--- [N] COG1558 Flagellar basal body rod protein FlgC 6 -----qv-e---uj--o---- [N] COG1706 Flagellar basal-body P-ring protein FlgI 3 ------v-eb----------- [N] COG1705 Flagellar biosynthesis protein FlgJ, probable N-acetylmuramidase 10 -----qv-eb--uj--olin- [N] COG1987 Flagellar biosynthesis/export protein FliQ 10 -----qv-eb--uj--olin- [N] COG1684 Flagellar biosynthetic protein FliR 8 -----qv-eb--uj--ol--- [N] COG1843 Flagellar hook capping protein FlgD 8 -----qv-eb--uj--ol--- [N] COG1256 Flagellar hook-associated protein FlgK 8 -----qv-eb--uj--ol--- [N] COG1345 Flagellar hook-associated protein FliD 8 -----qv-eb--uj--ol--- [N] COG1677 Flagellar hook-basal body protein FliE 9 -----qv-eb--uj--ol--- [N] COG1291 Flagellar motor component MotA 27 -----qv-ebrhuj--olinx [N] COG1360 Flagellar motor protein MotB and related proteins, PAL/OmpA family 12 -----qv-eb--uj--olin- [N] COG1536 Flagellar motor switch protein FliG 8 -----qv-eb--uj--ol--- [N] COG1868 Flagellar motor switch protein FliM 12 -----qv-eb--uj--olin- [N] COG1886 Flagellar motor switch protein FliN 8 -----qv-eb--uj--ol--- [N] COG1516 Flagellar protein FliS 5 -----qv--b--uj------- [N] COG1334 Flagellin 22 -----qv-eb--uj--ol--- [N] COG1344 Flagellin and related hook-associated protein FlgL 12 -----qvce--h------in- [N] COG1450 General secretion pathway protein D 11 -----qvceb-h------in- [N] COG1459 General secretion pathway protein F 4 -----q--e---------in- [N] COG2165 General secretion pathway protein G 11 --------e-rhuj----inx [N] COG1560 Lauroyl/myristoyl acyltransferase involved in lipid A biosynthesis 8 -----q--e--huj----inx [N] COG1663 Lipid A biosynthesis protein LpxK, tetraacyldisaccharide-1-P 4'-kinase 16 -----qvcebrhujgpolinx [N] COG0597 Lipoprotein signal peptidase 12 -----q--eb-h----o-in- [N] COG1388 LysM-repeat proteins and domains 8 -------cebrhuj------x [N] COG1217 Membrane GTPase 17 ----yqvcebrhujgpolinx [N] COG0481 Membrane GTPase LepA 13 -----qv-eb--uj--olin- [N] COG1298 Membrane protein FlhA involved in flagellum assembly 11 -----qv-eb--uj--olin- [N] COG1338 Membrane protein FliP involved in flagellar biogenesis 12 -----q--ebrhuj--olinx [N] COG1314 Membrane protein SecG involved in protein secretion 9 -----qv-eb--uj--ol--- [N] COG1580 Membrane-associated flagellar protein FliL 51 a--k--vceb--uj--ol--- [N] COG0840 Methyl-accepting chemotaxis protein 10 a--k--v-eb------ol--- [NT] COG1352 Methylase of chemotaxis methyl-accepting proteins 10 a------ce--huj----inx [N] COG0823 Periplasmic component of the Tol biopolymer transport system 26 amtk-qvcebrhuj---linx [N] COG0616 Periplasmic serine proteases 4 a--k-q---b----------- [N] COG1030 Periplasmic serine proteases (ClpP class) 37 amtk-qvcebrhuj----inx [N] COG0630 Predicted ATPases involved in pili biogenesis 14 a--k--v--b----gpol--- [N] COG1744 Predicted lipoprotein, Med/BMP family 10 -----qv-eb--uj--olin- [N] COG1377 Predicted membrane protein FlhB involved in flagellar biogenesis 17 -----qvcebrhujgpolinx [N] COG0653 Preprotein translocase subunit SecA (ATPase, RNA helicase) 4 -m------e--h--------x [N] COG1952 Preprotein translocase subunit SecB 16 -----qvcebrhujgpolinx [N] COG0690 Preprotein translocase subunit SecE 22 amtkyqvcebrhujgpolinx [N] COG0201 Preprotein translocase subunit SecY 17 -mtk-qvcebrhuj--olinx [N] COG0342 Preprotein translocase subunits SecD 17 -mtk-qvcebrhuj--olinx [N] COG0341 Preprotein translocase subunits SecF 11 -----qvcebrhuj--ol--- [N] COG0758 Protein involved in DNA uptake 12 a----q-cebrhuj------x [N] COG0805 Sec-independent protein secretion pathway component TatC 7 -----qvceb-h--------- [N] COG1989 Signal peptidase HopD, cleaves prepilin-like proteins 35 amtkyqvcebrhuj--olinx [N] COG0681 Signal peptidase I 5 amtky---------------- [N] COG1400 Signal recognition particle 19 kDa protein 21 amtkyqvcebrhujgpolinx [N] COG0541 Signal recognition particle GTPase Ffh 21 amtkyqvcebrhujgpolinx [N] COG0552 Signal recognition particle GTPase FtsY 3 ------v---------ol--- [N] COG1406 Uncharacterized ORF in a chemotaxis operon 4 -----qv-----uj------- [N] COG1261 Uncharacterized flagellar protein FlgA 4 ------v--b------ol--- [N] COG1582 Uncharacterized protein, possibly involved in motility 3 ------v-eb----------- [P] COG1535 2,3-Dihydro-2,3 dihydroxybenzoate synthase (isochorismate synthase) 8 ----yq-ce-rh------in- [P] COG1218 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase 25 a-tk-qvceb-h-----linx [P] COG1108 ABC-type Mn/Zn transport systems, ATPase component 28 amtk--vc-brh--gp-l--- [P] COG1122 ABC-type cobalt transport system, ATPase component 24 am-k--vceb-hujgp----- [P] COG1120 ABC-type iron (III) transport system, ATPase component 19 a-tk-qvceb-h-----linx [P] COG1121 ABC-type iron (III) transport system, ATPase component 4 ----y---ebr---------- [P] COG1119 ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA 15 am----vceb-h--------- [P] COG1116 ABC-type nitrate transport system, ATPase component 17 amt--qvcebrh--gpo---- [P] COG1117 ABC-type phosphate transport system, ATPase component 12 amtk---ce-rh-------n- [P] COG1118 ABC-type sulfate/molybdenum transport system, ATPase component 6 a---yq-c-b----------- [P] COG2046 ATP sulfurylase 11 a---yq-cebr---------- [P] COG0529 Adenylylsulfate kinase and related kinases 5 ----y-v-eb----------- [P] COG1785 Alkaline phosphatase 18 amt-yqvcebr---------- [P] COG0004 Ammonia permeases 11 --------eb-h--gp----- [P] COG1393 Arsenate reductase ArsG and related proteins, glutaredoxin family 9 a-tky-vc-br---------- [P] COG0798 Arsenite efflux pump ACR3 and related permeases 17 a--k--vcebr-------in- [P] COG1055 Arsenite permease 9 -mt-yq-c--r---------- [P] COG0003 Arsenite transporting ATPase 4 -------ce-r---------- [P] COG2193 Bacterioferritin (cytochrome b1) 6 ----y--cebr---------- [P] COG0387 Ca2+/H+ antiporter 13 amtkyqvce-------ol--- [P] COG0530 Ca2+/Na+ antiporter 14 --t-y--cebrhuj------- [P] COG0288 Carbonic anhydrase 11 ----y---eb-huj------- [P] COG0753 Catalase 5 a---y--ce-r---------- [P] COG0376 Catalase (peroxidase I) 27 -----qvceb-huj--o---x [P] COG0841 Cation efflux system protein 33 -mt-yq-cebr---gp----- [P] COG0474 Cation transport ATPases 40 amt-yqvcebrhuj---lin- [P] COG2217 Cation transport ATPases 24 -mtkyq-ceb-huj----in- [P] COG0471 Cation transporters 8 -m----vc-b------o---- [P] COG2059 Chromate transport protein ChrA 6 ---kyqv-eb----------- [P] COG1230 Co/Zn/Cd efflux system component 19 amtk--vc-brh--gp----- [P] COG0619 Cobalt permease and related transporters 3 amt------------------ [P] COG1930 Cobalt transport protein CbiN 6 ----yq--ebr---------- [P] COG2032 Cu/Zn superoxide dismutase 3 -----q-ce------------ [P] COG1513 Cyanate lyase 4 -----q--e---uj------- [P] COG1858 Cytochrome c peroxidase 37 amtkyqvcebrhuj------x [P] COG1226 Eukaryotic-type potassium channels 7 amt---vce------------ [P] COG1918 FeoA protein, probably involved in Fe2+ transport 16 ------vcebr---------- [PR] COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases 22 a----qvcebrhujgpo---- [P] COG0735 Ferric uptake regulation protein 33 am-k--vcebrhuj------- [P] COG0614 Ferrichrome-binding periplasmic proteins 10 a-t---v-e-rhuj------- [P] COG1528 Ferritin-like protein Rsg 12 amtk-qvce---uj------- [P] COG0370 Ferrous ion uptake system protein FeoB (predicted GTPase) 8 ----y---eb-h--------- [P] COG2116 Formate/nitrite family of transporters 9 a---y-vceb-------l--x [P] COG0672 High-affinity iron permease 3 -------ce-r---------- [P] COG2216 High-affinity potassium transport system, ATPase chain B 32 am-k--vceb-huj------- [PH] COG0609 Iron, hemin, cobalamine permeases 28 amtkyq-cebrhuj--o---x [P] COG0475 K efflux system, membrane domain 3 -------ce-r---------- [P] COG2060 K+-transporting ATPase, A chain 3 -------ce-r---------- [P] COG2156 K+-transporting ATPase, c chain 13 -------cebrhuj------x [P] COG0861 Membrane protein TerC, possibly involved in tellurium resistance 12 --------ebr---------- [P] COG2076 Membrane transporters of cations and cationic drugs 18 am-kyqvcebrhuj------- [P] COG0598 Mg and Co transporters 10 --t---vc-br-----olinx [P] COG2239 Mg/Co/Ni transporter MgtE (contains CBS domain) 14 amtk-q-cebrhuj------- [P] COG0725 Molybdenum-binding periplasmic protein 13 amt-y--cebr---------- [P] COG0025 Na+/H+ antiporter (eukaryotic type) 4 --------ebr---------- [P] COG1140 Nitrate reductase beta chain 9 -----q--ebr---------- [P] COG2223 Nitrate/nitrite transporter 4 -mt----c------------- [P] COG1348 Nitrogenase subunit NifH (ATPase) 39 -----q-ce--huj------- [P] COG1629 Outer membrane receptor proteins, mostly Fe transport 3 am-------b----------- [P] COG1910 Periplasmic molybdate-binding protein (domain) 20 amt--qvcebrh--gpo---- [P] COG0226 Periplasmic phosphate-binding protein 4 -------ce-r---------- [P] COG1613 Periplasmic sulfate/thiosulfate binding proteins 12 am-kyq-ce-r---------- [P] COG0038 Permease, putative chloride channel 3 a-tk----------------- [P] COG1824 Permease, similar to cation transporters 15 amt--qvcebrh--gpo---- [P] COG0573 Phosphate permease 20 amtky-v-ebrhuj----in- [P] COG0306 Phosphate permease 14 amt--qvcebrh----o---- [P] COG0581 Phosphate permease component of ATP-dependent phosphate uptake system 22 amtk-qvce-r---gpo---- [P] COG0704 Phosphate uptake regulator 5 -------ce-r-uj------- [P] COG0855 Polyphosphate kinase 26 amtk-qvcebrh--gpol--- [P] COG0569 Potassium uptake system NAD-binding component TrkA 18 amtkyqvceb-h--gpol--- [P] COG0168 Potassium uptake system component TrkG 19 amt-yqvcebr-----o---x [P] COG0053 Predicted Co/Zn/Cd cation transporters 10 -mtkyqv-e-r-----o---- [P] COG0428 Predicted divalent heavy-metal cations transporter 11 ----y--c-br---------- [P] COG2072 Predicted flavoproteins involved in potassium transport 4 ----y---e-r---------- [P] COG2175 Probable taurine catabolism dioxygenase TauD, TfdA family 4 ----y---e--h--------x [P] COG1965 Protein implicated in iron transport, frataxin homolog 6 ----y---ebr---------- [P] COG1914 Putative Mn transporter, NRAMP family 3 -----q--eb----------- [P] COG1276 Putative copper export protein 5 a----q---br---------- [P] COG0490 Putative regulatory, ligand-binding protein related to C-terminal domains of potassium channels 21 a---y-vceb-h------in- [P] COG0715 Putative taurine-binding periplasmic protein 41 amt-yq-cebrhuj--o---x [P] COG0607 Rhodanese-related sulfurtransferases 19 ----yq-cebr-uj----in- [P] COG0659 Sulfate permease and related transporters (MFS superfamily) 10 ----y--ceb--------in- [P] COG0369 Sulfite reductase flavoprotein subunit 9 a---yq-cebr---------- [P] COG0155 Sulfite reductase hemoprotein beta-component 18 --t-yq-cebrhuj--o-inx [P] COG0605 Superoxide dismutase 7 am-k----e-rh--------- [P] COG1275 Tellurite resistance protein and related permeases 6 -mt---v-e--h--------- [P] COG1553 Uncharacterized ACR involved in intracellular sulfur reduction 8 a-tk-qv-e----------nx [P] COG1324 Uncharacterized protein CutA involved in tolerance to divalent cations 3 --t---v-e------------ [P] COG2168 Uncharacterized protein DsrH, involved in oxidation of intracellular sulfur 22 a-tk-qvcebrh-----linx [P] COG0803 Zn-binding (lipo)protein of the ABC-type Zn transport system (surface adhesin A) 15 -----q--e---uj--olinx [T] COG2204 AAA superfamily ATPases with N-terminal receiver domain 11 -------c--r------l--- [T] COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain) 27 ------vc-br------lin- [T] COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) 6 ------v--br-------in- [T] COG2172 Anti-sigma regulatory factor (Ser/Thr protein kinase) 15 am-k----------------- [T] COG1848 Archaeal proteins containing PIN domain 8 -----q--ebrhuj------- [T] COG1966 Carbon starvation protein CstA, predicted membrane protein 8 ------v-eb-huj--ol--- [T] COG1551 Carbon storage regulator (could also regulate swarming and quorum sensing) 115 a-tkyqvcebrhuj--ol--x [T] COG0784 CheY-like receiver domains 19 -----qv-ebrh--------x [T] COG1278 Cold shock proteins 27 am-ky-vceb-h--------- [T] COG0639 Diadenosine tetraphosphatase and related serine/threonine protein phosphatases 70 -----qvcebr-----ol--x [T] COG2199 Diguanylate cyclase/phosphodiesterase domain 1 (GGDEF) 42 -----q-cebr-----o---x [T] COG2200 Diguanylate cyclase/phosphodiesterase domain 2 (EAL) 12 -----q--eb-h----olinx [T] COG1734 DnaK suppressor protein DskA 35 a-t--q-ce-r---------- [T] COG2203 GAF domain 4 ----y-v-eb----------- [T] COG1956 GAF domain-containing proteins 14 -----qvcebrhujgpo---- [TK] COG0317 Guanosine polyphosphate pyrophosphohydrolases/synthetases 17 -----qvc--------ol--- [T] COG2206 HD-GYP domain 6 --------eb-huj--o---- [T] COG1854 LuxS protein involved in autoinducer AI2 synthesis 3 -------ce-r---------- [T] COG2205 Osmosensitive K+ channel His kinase sensor domain 75 a-t--qvcebr-------i-- [T] COG2202 PAS/PAC domain 6 am-k---c------------- [T] COG1569 PIN domain 7 -----qvcebr---------- [T] COG1702 Phosphate starvation-inducible protein PhoH, predicted ATPase 7 a----q-ce-rh--------- [T] COG2062 Phosphohistidine phosphatase SixA 5 ------v--br-------in- [T] COG1875 Predicted ATPase related to phosphate starvation-inducible protein PhoH 4 am-k-q--------------- [T] COG2112 Predicted Ser/Thr protein kinase 4 am-ky---------------- [T] COG0478 Predicted serine/threonine protein kinases 5 amtky---------------- [T] COG1718 Predicted serine/threonine protein kinases 19 ----yq-c-br---gp--in- [T] COG0631 Protein serine/threonine phosphatases 15 a-t-yq-cebr---------- [T] COG0394 Protein-tyrosine-phosphatase 32 amtkyqvc------------- [T] COG0467 RecA-superfamily ATPases implicated in signal transduction 44 -------cebrh--------- [TK] COG2197 Response regulators consisting of a CheY-like receiver domain and a HTH DNA-binding domain 77 -----qvcebrhuj----inx [TK] COG0745 Response regulators consisting of a CheY-like receiver domain and a HTH DNA-binding domain 195 a-t-yqvcebrhuj--o-inx [T] COG0642 Sensory transduction histidine kinases 4 ---------b----gp-l--- [T] COG1493 Serine kinase of the HPr protein, regulates carbohydrate metabolism 15 ------vc-br------lin- [TK] COG2208 Serine phosphatase RsbU, regulator of sigma subunit 155 amtkyq-c-br---gp-lin- [T] COG0515 Serine/threonine protein kinases 9 ----y--ce--h--------x [T] COG0271 Stress-induced morphogen BolA (activity unknown) 11 ----y--ce--h--------- [T] COG2198 Two component signal transduction system HPt domain 48 amtk-q-cebrh--------x [T] COG0589 Universal stress protein UspA and related nucleotide-binding proteins 41 a---yqvcebrh-----lin- [T] COG0664 cAMP-binding domains - Catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases 8 amtk--v--b----------- [C] COG1668 ATP-dependent Na+ efflux pump membrane component NatB 17 ------vcebrhujgpol--x [C] COG0282 Acetate kinase 5 amt------------------ [C] COG1152 Acetyl-CoA decarbonylase/synthase, subunit alpha 5 a---y--ce------------ [C] COG0427 Acetyl-CoA hydrolase 8 ----yq--ebr---------x [C] COG1048 Aconitase A 4 -------ce---uj------- [C] COG1049 Aconitase B 14 am-k----e------------ [C] COG1042 Acyl-CoA synthetases 9 am----v-eb------o---- [C] COG1254 Acylphosphatases 7 -----q--ebr------l--- [C] COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs 7 --------ebr-----ol--- [C] COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs 7 --------ebr-----ol--- [C] COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs 14 a-tkyqv-eb----------- [C] COG1454 Alcohol dehydrogenase IV 10 ----y-vce-rh--------- [CR] COG1062 Alcohol dehydrogenase class III and related dehydrogenases 43 amtk-q-cebrhuj------- [C] COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing 9 ----y--cebrh----o---- [C] COG0578 Anaerobic glycerol-3-phosphate dehydrogenase 6 amt------------------ [C] COG1036 Archaeal flavoproteins 10 amtky-----------olin- [C] COG1394 Archaeal/vacuolar type H+-ATPase subunit D 5 amtky---------------- [C] COG1390 Archaeal/vacuolar type H+-ATPase subunit E 5 amtky---------------- [C] COG1527 Archaeal/vacuolar-type H+-ATPase subunit C (NtpC, VMA6) 6 amtky------------l--- [C] COG1436 Archaeal/vacuolar-type H+-ATPase subunit F (NtpG, VMA7) 11 amtky-----------olin- [C] COG1269 Archaeal/vacuolar-type H+-ATPase subunit I 4 amt------------------ [C] COG1614 CO dehydrogenase/acetyl-CoA synthase beta subunit 6 amt--q--------------- [C] COG1880 CO dehydrogenase/acetyl-CoA synthase epsilon subunit 20 a-t-yqvcebr-uj------x [C] COG0372 Citrate synthase 12 amt----c------------- [C] COG1035 Coenzyme F420 hydrogenase, beta chain 7 amtk---c------------- [C] COG1941 Coenzyme F420 hydrogenase, gamma chain 35 amt-----ebr---------- [C] COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases 8 -----q-c-br-uj------x [C] COG1290 Cytochrome b (b6-like) 11 a-------ebr-uj----inx [C] COG2142 Cytochrome b subunit of fumarate reductase and succinate dehydrogenase 4 ----y---e-----------x [C] COG2009 Cytochrome b subunit of succinate dehydrogenase 10 -----q-cebrh------inx [C] COG1294 Cytochrome bd quinol oxidase and cytochrome oxidase complexes, subunit 2 13 a----q-cebrh------inx [C] COG1271 Cytochrome bd quinol oxidase, subunit 1 11 -----q-cebr-uj------x [C] COG0843 Cytochrome c oxidase, heme b and copper-binding subunit 6 ---------br-uj------- [C] COG2010 Cytochrome c, mono- and diheme variants 11 a----q-cebr---------x [C] COG1622 Cytochrome oxidase aa3/quinol oxidase, subunit II 8 -----q-cebr---------x [C] COG1845 Cytochrome oxidase/quinol oxidases, subunit 3 24 amtkyqvce-r---------- [C] COG0644 Dehydrogenases (flavoproteins) 7 amtk--v----------l--- [C] COG2033 Desulfoferrodoxin 18 ---k-q--ebrh----olinx [C] COG1301 Dicarboxylate permease, Na+ or H+ symporter 26 ----y--cebrh--gp--inx [C] COG0508 Dihydrolipoamide acyltransferases 31 amt-yqvcebrh--gp--inx [C] COG1249 Dihydrolipoamide dehydrogenase/glutathione oxidoreductase and related enzymes 8 a---y-v-ebr---------- [C] COG2025 Electron transfer flavoprotein alpha-subunit 8 a---y-v-ebr---------- [C] COG2086 Electron transfer flavoprotein beta-subunit 6 am--y-v--b----------- [C] COG1227 Exopolyphosphatase 39 a---yq-cebrhuj------- [C] COG0277 FAD/FMN-containing dehydrogenases 34 amt--q-cebrhuj------- [C] COG0247 Fe-S oxidoreductases 4 -mtk---c------------- [C] COG1625 Fe-S oxidoreductase, related to NifB/MoaA family 11 amtky-vc----uj------- [C] COG0731 Fe-S oxidoreductases 30 amtk-qvcebrhuj---l-nx [C] COG0621 Fe-S oxidoreductases family 1 29 amtk--vce-r---------- [C] COG1032 Fe-S oxidoreductases family 2 21 a----q-ce--h--------- [C] COG0437 Fe-S-cluster-containing hydrogenase components 1 20 amtk--vce------------ [C] COG1142 Fe-S-cluster-containing hydrogenase components 2 21 a---yq-ce--h------inx [C] COG0633 Ferredoxin 7 a-t---v--br---------- [C] COG1141 Ferredoxin 1 64 amtk--vceb-huj------- [C] COG1145 Ferredoxin 2 38 amtk--vce-r-uj------x [C] COG1146 Ferredoxin 3 11 amtk-qv-----uj------- [C] COG1144 Ferredoxin-like subunits of formate hydrogenlyase 11 ----y---ebr---------- [C] COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 18 amt-y--ceb-huj---l--- [C] COG0716 Flavodoxins 15 -----qvcebrhujgp----x [C] COG0711 FoF1-type ATP synthase B subunit 12 -----qvcebrhujgp----x [C] COG0356 FoF1-type ATP synthase a subunit 13 ----yqvcebrhujgp----x [C] COG0056 FoF1-type ATP synthase alpha subunit 13 ----yqvcebrhujgp----x [C] COG0055 FoF1-type ATP synthase beta subunit 24 amtkyqvcebrhujgpolinx [C] COG0636 FoF1-type ATP synthase c subunit/Vacuolar ATPase/archaeal ATP synthase K subunit 11 ----yqvcebrh--gp----x [C] COG0712 FoF1-type ATP synthase delta subunit 13 ----yqvcebrhujgp----x [C] COG0355 FoF1-type ATP synthase epsilon subunit 14 ----yqvcebrhujgp----x [C] COG0224 FoF1-type ATP synthase gamma subunit 22 amtk--vcebr---------x [C] COG0651 Formate hydrogenlyase subunit 3, HycC 10 -mtk--v-e-r---------- [C] COG0650 Formate hydrogenlyase subunit 4, HycD 19 amtk-qvce-r-uj------x [C] COG0649 Formate hydrogenlyase subunit 5 and NADH-ubiquinone oxidoreductase 49 kD subunit 7 (chain D), NuoD/NQO4/Nad7 15 -mtk-qvce-r-uj------x [C] COG1143 Formate hydrogenlyase subunit 6/NADH-ubiquinone oxidoreductase 23 kD subunit (chain I), NuoI/NQO9/FrxB 3 amt------------------ [C] COG1229 Formylmethanofuran dehydrogenase subunit A 5 amt------------------ [C] COG1029 Formylmethanofuran dehydrogenase subunit B 4 amt------------------ [C] COG2218 Formylmethanofuran dehydrogenase subunit C 4 amt------------------ [C] COG1153 Formylmethanofuran dehydrogenase subunit D 5 amt------------------ [C] COG2037 Formylmethanofuran:tetrahydromethanopterin formyltransferase 11 ----y--cebrhuj----inx [C] COG0114 Fumarase 9 a--ky-v-e-rh--------- [C] COG1085 Galactose-1-phosphate uridylyltransferase 19 a-t-yqvcebrhuj--olinx [C] COG0240 Glycerol 3-phosphate dehydrogenase 10 amtk--vceb----------- [C] COG0371 Glycerol dehydrogenase 13 a---yqvcebrh--gpo---- [C] COG0554 Glycerol kinase 17 ----y-v-ebrh--gp-l--- [C] COG0584 Glycerophosphoryl diester phosphodiesterase 4 ----yq--eb----------- [C] COG1017 Haemoglobin-like flavoprotein 7 amt--q-c------------- [C] COG2048 Heterodisulfide reductase subunit B 6 amt--q--------------- [C] COG1150 Heterodisulfide reductase, subunit C 16 amtk-q-ce---uj------- [C] COG0680 Hydrogenase formation/expression factor HyaD/HupD 16 --tkyq-ce-rhujgp--inx [C] COG0221 Inorganic pyrophosphatase 12 a---yqvcebr-uj------- [C] COG0538 Isocitrate dehydrogenases 6 ----y---e-r---------- [C] COG2224 Isocitrate lyase 15 amtky--cebrh----ol--x [C] COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases 11 a-------eb-huj--o---- [C] COG1620 L-lactate permease 24 a--kyq-cebrhuj---l--- [CHR] COG1052 Lactate dehydrogenase and related dehydrogenases 5 ----y---e-r---------- [C] COG2225 Malate synthase 8 -mtk----eb-h--------- [C] COG2055 Malate/L-lactate dehydrogenases 21 amt-yqvcebrh--gpo-inx [C] COG0039 Malate/lactate dehydrogenases 14 a--ky-vcebrh--------x [C] COG0281 Malic enzyme 5 ------v-e--h----ol--- [C] COG1726 Membrane-bound Fe-S proteins, RfnC family 10 amtk--v-------------- [C] COG1149 MinD superfamily P-loop ATPases containing an inserted ferredoxin domain 13 -mtk--vc-b----------x [C] COG2111 Multisubunit Na+/H+ antiporter, MnhB subunit 10 -mtk--vc-b----------x [C] COG1006 Multisubunit Na+/H+ antiporter, MnhC subunit 8 -mtk--v--b----------x [C] COG1863 Multisubunit Na+/H+ antiporter, MnhE subunit 5 --tk--v--b----------x [C] COG2212 Multisubunit Na+/H+ antiporter, MnhF subunit 8 -mtk--v--b----------x [C] COG1320 Multisubunit Na+/H+ antiporter, MnhG subunit 3 amt------------------ [C] COG1927 N5,N10-methylenetetrahydromethanopterin dehydrogenase 5 -------ce-rh--------x [C] COG1282 NAD(P)+ transhydrogenase, beta subunit 5 -----q--ebr---------- [C] COG1251 NAD(P)H:nitrate reductase 51 -mt-yq-cebr-uj------- [C] COG1012 NAD-dependent aldehyde dehydrogenases 13 ----y--cebrhuj------x [C] COG0686 NAD/NADP transhydrogenase alpha subunit 12 --t--qvcebr-uj------x [C] COG1034 NADH dehydrogenase 75 kD subunit (chain G), NuoG/NQO3/Nad11 14 ----y--cebrh--------- [C] COG1252 NADH dehydrogenase, FAD-containing subunit 10 --t--qvce-r---------x [C] COG1905 NADH-ubiquinone oxidoreductase 24 kD subunit, NuoE/NQO2 15 a--k-qvce-r-uj------x [C] COG0852 NADH-ubiquinone oxidoreductase 27 kD subunit, NuoC/NQO5/Nad9 10 a----q-ce-r-uj------x [C] COG1005 NADH-ubiquinone oxidoreductase subunit 1 (chain H), NuoH/NQO8/Nad1 8 -----q-ce-r-uj------x [C] COG0713 NADH-ubiquinone oxidoreductase subunit 11 or 4L (chain K), NuoK/NQO11/Nad4L 8 -----q-ce-r-uj------x [C] COG1007 NADH-ubiquinone oxidoreductase subunit 2 (chain N), NuoN/NQO14/Nad2 8 -----q-ce-r-uj------x [C] COG0838 NADH-ubiquinone oxidoreductase subunit 3 (chain A), NuoA/NQO7/NdhC 11 -----q-ce-r-uj------x [C] COG1008 NADH-ubiquinone oxidoreductase subunit 4 (chain M), NuoM/NQO13/Nad4 15 a----q-cebr-uj------x [C] COG1009 NADH-ubiquinone oxidoreductase subunit 5 (chain L), NuoL/NQO12/Nad5 8 -----q-ce-r-uj------x [C] COG0839 NADH-ubiquinone oxidoreductase subunit 6 (chain J), NuoJ/NQO10/Nad6 9 --t--qvce-r---------x [C] COG1894 NADH-ubiquinone oxidoreductase, NADH-binding (51 kD) subunit, NuoF/NQO1 12 a---y-v-ebr---------- [C] COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family 19 amtk-qvce-r-uj------x [C] COG0377 NADH:ubiquinone oxidoreductase 20 kD subunit NuoB/Nqo6/NdhK and related Fe-S oxidoreductases 22 ----yq--ebr---------- [CR] COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases 6 ------v-e--h------in- [C] COG2209 Na+-translocating NADH-quinone oxidoreductase, subunit 5 (NqrE) 6 ------v-e--h------in- [C] COG1347 Na+-translocating NADH-quinone reductase, subunit 5 4 a--k--v----------l--- [C] COG1883 Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit 9 ---k-----b-huj--o---- [C] COG1757 Na+/H+ antiporter NhaC 16 amtk-q-ce---uj------- [C] COG0374 Ni/Fe hydrogenase alpha subunit 4 -----q--e---uj------- [C] COG1969 Ni/Fe hydrogenase cytochrome b subunit 8 a----q--e---uj------- [C] COG1740 Ni/Fe hydrogenases, small subunit 6 amt------------------ [C] COG1908 NiFe-type hydrogenase (viologen-reducing), delta subunit 18 a---yqv-ebrhujgp-linx [C] COG0822 NifU homologs involved in Fe-S cluster formation 5 --------ebr---------- [C] COG2180 Nitrate reductase delta subunit 8 a-------ebr---------- [C] COG2181 Nitrate reductase gamma subunit 32 amt--qvcebrhuj------- [C] COG0778 Nitroreductase family proteins 5 amt------------------ [C] COG2221 Oxidoreductases related to nitrate reductase 5 ---k------r------lin- [C] COG1274 Phosphoenolpyruvate carboxykinase 4 ----y---eb-h--------- [C] COG1866 Phosphoenolpyruvate carboxykinase 18 ------vcebrh-jgpol--x [C] COG0280 Phosphotransacetylase 4 --------eb-----p----- [C] COG2213 Phosphotransferase system, mannitol-specific IIBC component 10 am----vce--huj------- [C] COG0348 Polyferredoxin 8 amt--qv-------------- [C] COG1148 Polyferredoxins 12 a-------e-r---------- [C] COG1804 Predicted acyl-CoA transferases/carnitine dehydratase 27 ----yqvcebr-u---o---- [C] COG0667 Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) 8 ----y---ebrh------inx [C] COG0567 Pyruvate and 2-oxoglutarate dehydrogenases, E1 component 9 a-t-----e--h--------- [C] COG1882 Pyruvate-formate lyase 34 amtkyqvce-r-uj---l--- [C] COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit 32 amtkyqvce-r-uj---l--- [C] COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit 30 amtk-qvce-r-uj---l--- [C] COG1014 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit 4 ----y---eb----------- [C] COG1069 Ribulose kinase 12 ----yq-c-br-uj------x [C] COG0723 Rieske Fe-S protein 13 amt---vce-r------l--- [C] COG1773 Rubredoxin 10 amt---v--b----------- [C] COG1592 Rubrerythrin 20 amt-yq-cebrhuj----inx [C] COG0479 Succinate dehydrogenase/fumarate reductase Fe-S protein 26 amt-yqvcebrhuj----inx [C] COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunits 15 amt-yq-cebrh------inx [C] COG0045 Succinyl-CoA synthetase beta chain 17 amt-yq-cebrh------inx [C] COG0074 Succinyl-CoA synthetase, alpha subunit 10 amtk-qv-e------------ [C] COG1951 Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain 11 amtk-qv-e------------ [C] COG1838 Tartrate dehydratase beta subunit/Fumarate hydratase class I, C-terminal domain 14 ----y--c-br---gp--inx [C] COG1071 Thiamine pyrophosphate-dependent dehydrogenases, E1 component alpha subunit 13 ----y--c-br---gp--inx [C] COG0022 Thiamine pyrophosphate-dependent dehydrogenases, E1 component beta subunit 5 a-tk----------------- [C] COG2191 Tungsten formylmethanofuran dehydrogenase, subunit E, FwdE 4 am-k--v-------------- [C] COG1031 Uncharacterized Fe-S oxidoreductases 5 a-t----ceb----------- [C] COG1600 Uncharacterized Fe-S protein 6 a-t-----eb--uj------- [C] COG1139 Uncharacterized conserved protein containing a ferredoxin-like domain 18 amtk-qvce------------ [C] COG0426 Uncharacterized flavoproteins 4 ------v-eb----------- [C] COG1979 Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenasefamily 7 amt-----ebrh--------- [C] COG1526 Uncharacterized protein FdhD/NarQ required for formate dehydrogenase activity 12 amtky-----------olin- [C] COG1155 Vacuolar ATPase/archaeal ATP synthase A subunit (NtpA) 10 amtky-----------olin- [C] COG1156 Vacuolar ATPase/archaeal ATP synthase B subunit (NtpB) 10 ----yq-cebrh------in- [G] COG0296 1,4-alpha-glucan branching enzyme 4 -mtk----------------- [G] COG2074 2-Phosphoglycerate kinase 9 ------vceb-huj---l--- [G] COG0800 2-keto-3-deoxy-6-phosphogluconate aldolase 10 amtk----eb-h---p----- [G] COG0269 3-hexulose-6-phosphate synthase and related proteins 20 amtkyqvcebrhujgpolin- [G] COG0126 3-phosphoglycerate kinase 8 -----q-ce-rh----o-in- [G] COG1640 4-alpha-glucanotransferase 21 ----yqvcebrh--gpolin- [G] COG0205 6-phosphofructokinase 13 ----y-vcebrh----olin- [G] COG0362 6-phosphogluconate dehydrogenase, family 1 3 -----q---br---------- [G] COG1023 6-phosphogluconate dehydrogenase, family 2 10 a----q-c-br---------x [G] COG1134 ABC-type polysaccharide/polyol phosphate transport system, ATPase component 25 a--k--v-eb-h--gpol--- [G] COG1129 ABC-type sugar (aldose) transport system, ATPase component 38 amtk--vcebrh--gpol--- [G] COG1130 ABC-type sugar transport system, ATPase component 35 ---k--vcebr---gp-l--- [G] COG1175 ABC-type sugar transport systems, permease components 10 ------vcebrh------in- [G] COG0448 ADP-glucose pyrophosphorylase 4 -m-k-q-c------------- [G] COG1449 Alpha-amylase/alpha-mannosidase 12 ------v-eb----------- [G] COG1486 Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases 4 ----y-v-e------------ [G] COG1501 Alpha-glucosidases, family 31 of glycosyl hydrolases 7 ---ky-vce-r---------- [G] COG0383 Alpha-mannosidase 5 ----y-v--b----------- [G] COG1621 Beta-fructosidases (levanase/invertase) 5 ---k--v--b----------- [G] COG1874 Beta-galactosidase 5 ----y-v--b----------- [G] COG1789 Beta-glucanase 13 ------vcebrh----o---x [G] COG1472 Beta-glucosidase-related glycosidases 16 amtk--v-eb----------- [G] COG1363 Cellulase M and related proteins 4 ------v-eb-h--------- [G] COG1312 D-mannonate dehydratase 11 amtk-q--e---------in- [G] COG1830 DhnA-type fructose-1,6-bisphosphate aldolase and related enzymes 8 ------vceb-h--------- [G] COG1638 Dicarboxylate-binding periplasmic protein 26 amtkyqvcebrhujgpolin- [G] COG0148 Enolase 6 ----y--ce--huj------- [G] COG0158 Fructose-1,6-biphosphatase 6 -------cebrh--------- [G] COG1494 Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase and related proteins 9 ------v-ebrh--gpo---- [G] COG1105 Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) 18 ----yqvcebrhujgpol--- [G] COG0191 Fructose/tagatose biphosphate aldolases 6 ----y---eb-huj------- [G] COG0738 Fucose permease 10 ---ky-vcebrh-----l--- [G] COG0153 Galactokinase 9 ----y-v-eb-h--------- [G] COG2017 Galactose mutarotase and related enzymes 13 -m-kyq-cebrh------in- [G] COG0058 Glucan phosphorylase 4 -------ce---uj------- [G] COG0837 Glucokinase 21 ----y-vcebrhuj--olin- [G] COG0363 Glucosamine-6-phosphate deaminase (Glucosamine-6-phosphate isomerase) 3 -------ce-r---------- [G] COG2133 Glucose dehydrogenase 15 ----yqvcebrhuj--olin- [G] COG0364 Glucose-6-phosphate 1-dehydrogenase 17 -m--yqvcebrhujgpolin- [G] COG0166 Glucose-6-phosphate isomerase 3 ------v-eb----------- [G] COG1904 Glucuronate isomerase 28 amtkyqvcebrhujgpolin- [G] COG0057 Glyceraldehyde-3-phosphate dehydrogenase 16 a-t-y-vceb-h--gpo---- [G] COG0580 Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family) 11 -m-k-qvceb-h------in- [G] COG0297 Glycogen synthase 29 ----y-vcebr---------- [G] COG0366 Glycosidases 13 -mt-y--c-br---------- [GC] COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase 21 amtkyqvcebrh----o---x [G] COG0483 Inositol phosphatase family proteins 3 ------v-eb----------- [G] COG2160 L-arabinose isomerase 7 ---k--v-eb----------- [G] COG2182 Maltose-binding periplasmic proteins/domains 11 ----y-v-eb-----p----- [G] COG0246 Mannitol-1-phosphate/altronate dehydrogenases 15 amtk-qvcebr-uj------- [G] COG0662 Mannose-6-phosphate isomerase 6 ------vceb-h----o---- [G] COG1803 Methylglyoxal synthase 7 ------v-ebrh----o---- [G] COG1820 N-acetylglucosamine-6-phosphate deacetylase 6 ----y---e-------ol--- [G] COG1626 Neutral trehalase 18 -m--yqvcebrhujgp-lin- [G] COG0036 Pentose-5-phosphate-3-epimerase 16 ------v-eb-h-----l--- [G] COG1879 Periplasmic sugar-binding proteins 368 amtkyqvcebrhujgpo-inx [GER] COG0477 Permeases 11 -------ceb----------- [G] COG2211 Permeases of the Na+:galactoside symporter family 21 amtk-qvcebr-uj---l--x [G] COG0574 Phosphoenolpyruvate synthase 12 --------eb-h--gpo-in- [G] COG1080 Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) 5 ----y--ce-r---------- [G] COG0033 Phosphoglucomutase 10 ----y---e-rh----olin- [G] COG0588 Phosphoglycerate mutase 1 24 ----yqvcebr---------- [G] COG0406 Phosphoglycerate mutase/fructose-2,6-bisphosphatase 7 -------ceb--ujgp----- [G] COG0696 Phosphoglyceromutase 10 -m---q-ce-rhuj------- [G] COG0279 Phosphoheptose isomerase 44 amtkyqvcebrhujgpolinx [G] COG1109 Phosphomannomutase 9 a---y-v-ebr-----o---- [G] COG1482 Phosphomannose isomerase 15 amtk-qv-eb--uj------- [G] COG1015 Phosphopentomutase/predicted phosphoglycerate mutase and related enzymes 12 --------eb-h--gpo---- [G] COG2190 Phosphotransferase system IIA components 25 --------eb----gpo---- [G] COG1264 Phosphotransferase system IIB components 22 --------eb----gpo---- [G] COG1263 Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific 4 --------eb------o---- [G] COG1447 Phosphotransferase system cellobiose-specific component IIA 4 --------eb------o---- [G] COG1440 Phosphotransferase system cellobiose-specific component IIB 5 --------eb------o---- [G] COG1455 Phosphotransferase system cellobiose-specific component IIC 13 --------eb-h--gpo---- [G] COG1445 Phosphotransferase system fructose-specific component IIB 31 --------eb-h--gpolin- [GT] COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) 16 --------eb-h--gpolin- [G] COG1925 Phosphotransferase system, HPr-related proteins 12 --------eb-h--gpo---- [G] COG1299 Phosphotransferase system, fructose-specific IIC component 13 amtkyqvcebr-uj------- [G] COG0063 Predicted sugar kinase 12 a--kyqv-ebr---------x [G] COG0647 Predicted sugar phosphatases of the HAD superfamily 15 ----y-vcebr-uj------- [G] COG0726 Predicted xylanase/chitin deacetylase 9 ------vcebrh------in- [G] COG1523 Pullulanase and related glycosidases 19 -m-ky-vcebrh--gpo-in- [G] COG0469 Pyruvate kinase 12 amtky--ce--h----olin- [G] COG0120 Ribose 5-phosphate isomerase 11 -----qvcebr-ujgp----x [G] COG0698 Ribose 5-phosphate isomerase RpiB 17 ------v-eb-h-----l--- [G] COG1172 Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components 6 am-k---c-b----------- [G] COG1850 Ribulose 1,5-bisphosphate carboxylase, large subunit 25 amtkyqv-ebrhuj-p----x [G] COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases 24 a---y-vcebrh----ol--- [G] COG1070 Sugar (pentulose and hexulose) kinases 7 a-t--qvce--h--------- [G] COG1489 Sugar fermentation stimulation protein (uncharacterized) 40 amtkyqvcebrhuj------- [G] COG0524 Sugar kinases, ribokinase family 35 ---k--vcebr---gp-l--- [G] COG0395 Sugar permeases 20 ---k--vcebr------l--- [G] COG1653 Sugar-binding periplasmic proteins/domains 17 -m--yqvcebrhuj----in- [G] COG0176 Transaldolase 21 -m--yqvcebrhujgp-lin- [G] COG0021 Transketolase 6 ---ky---ebr---------- [G] COG1554 Trehalose and maltose hydrolases (possible phosphorylases) 5 --t-y---e-r---------- [G] COG1877 Trehalose-6-phosphatase 8 --t-y--ce-r---------- [G] COG0380 Trehalose-6-phosphate synthase 20 amtkyqvcebrhujgpolin- [G] COG0149 Triosephosphate isomerase 6 ------v-eb-h--------- [G] COG1869 Uncharacterized components of ribose/xylose transport systems 4 ----y--ce--h--------- [G] COG0676 Uncharacterized enzymes related to aldose 1-epimerase 4 ------v-eb-h--------- [G] COG2115 Xylose isomerase 13 -m-ky--cebr---------- [EH] COG0175 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes 17 amtkyqvcebrh--------- [E] COG0065 3-Isopropylmalate dehydratase large subunit 9 amt-yq--eb--------in- [E] COG0710 3-dehydroquinate dehydratase 7 ------vc-brhuj------- [E] COG0757 3-dehydroquinate dehydratase II 11 ----y-vcebrhuj----in- [E] COG0337 3-dehydroquinate synthetase 17 amtkyqvcebrh--------- [E] COG0066 3-isopropylmalate dehydratase small subunit 9 ---kyqvceb-h--------- [E] COG0685 5,10-methylenetetrahydrofolate reductase 15 amt-yqvcebrhuj----in- [E] COG0128 5-enolpyruvylshikimate-3-phosphate synthase 20 amtk-q-cebrhuj------- [EP] COG0555 ABC-type cysteine/molybdate transport systems, permease components 38 a--kyqv-eb-hujgpo-in- [EP] COG0444 ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component 39 a--k-qv-eb-hujgpo-in- [EP] COG1124 ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component 22 a-----vceb-huj----inx [E] COG1126 ABC-type polar amino acid transport system, ATPase component 10 a-------ebr-uj--o---- [E] COG1125 ABC-type proline/glycine betaine transport systems, ATPase components 10 a-----v-e--h--gpol--- [E] COG1176 ABC-type spermidine/putrescine transport system, permease component I 10 a-----v-e--h--gpol--- [E] COG1177 ABC-type spermidine/putrescine transport system, permease component II 12 amt-yqvcebrh--------- [E] COG0040 ATP phosphoribosyltransferase (histidine biosynthesis) 39 a-tk-q-cebrhuj----i-- [EPGR]COG1101 ATPase components of various transport systems 13 amt-yqvcebrh--------- [E] COG0440 Acetolactate synthase, small subunit 12 amtkyqvcebr---------- [E] COG0548 Acetylglutamate kinase 11 amtkyqvcebr---------- [E] COG0002 Acetylglutamate semialdehyde dehydrogenase 34 am-kyqv-ebrhuj-----nx [E] COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases 33 a-----vceb-huj----inx [E] COG0765 Amino acid ABC transporter permease component 25 ----y---e--huj----in- [E] COG0814 Amino acid permeases 58 amt-y--cebrh--gp--inx [E] COG0531 Amino acid transporters 26 ----y---eb--uj------- [E] COG0833 Amino acid transporters 8 ----y--ce-rh--------- [E] COG0308 Aminopeptidase N 13 amt-yqvcebrhuj------- [E] COG0547 Anthranilate phosphoribosyltransferase 23 amt-yqvcebrhuj------- [EH] COG0147 Anthranilate/para-aminobenzoate synthases component I 16 amt-yqvcebrhuj------- [EH] COG0512 Anthranilate/para-aminobenzoate synthases component II 3 amt------------------ [E] COG1411 Archaeal family of HisA paralogs 13 amtky--ceb--uj------- [E] COG0010 Arginase/agmatinase/formimionoglutamate hydrolase, arginase family 5 -------ce---uj------- [E] COG1166 Arginine decarboxylase (spermidine biosynthesis) 5 ----------r----po---- [E] COG2235 Arginine deiminase 6 ------v-ebrh-------n- [E] COG1438 Arginine repressor 10 -------cebrh--------- [E] COG1982 Arginine/lysine/ornithine decarboxylases 10 amt-yq-cebrh--------- [E] COG0165 Argininosuccinate lyase 11 amt-yqvcebrh--------- [E] COG0137 Argininosuccinate synthase 3 ---k---ce------------ [E] COG1446 Asparaginase 13 amtky---ebr---------- [E] COG0367 Asparagine synthase (glutamine-hydrolyzing) 6 ------v-eb-huj------- [E] COG1027 Aspartate ammonia-lyase 19 amtkyqvcebrhuj----inx [E] COG0136 Aspartate-semialdehyde dehydrogenase 7 ----y---e--h------in- [E] COG1448 Aspartate/aromatic aminotransferase 24 amtkyqvcebrhuj----inx [E] COG0527 Aspartokinases 6 ----y-v---r-----o---- [E] COG1362 Aspartyl aminopeptidase 4 am------e------------ [E] COG1775 Benzoyl-CoA reductase/2-hydroxyglutaryl-CoA dehydratase subunit, BcrC/BadD/HgdB 18 am----vce------------ [E] COG0559 Branched-chain amino acid ABC-type transport system, permease components 24 amt-yqvcebrhuj------x [EH] COG0115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase 7 --------eb-h-----lin- [E] COG1114 Branched-chain amino acid permeases 7 ---k---ce--h---p----- [E] COG0549 Carbamate kinase 18 amt-yqvcebr-uj------- [EF] COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ) 14 amt-yqvcebr-uj------- [EF] COG0505 Carbamoylphosphate synthase small subunit 13 amt--qv-ebrhuj------- [E] COG1605 Chorismate mutase 15 amt-yqvcebrhuj----in- [E] COG0082 Chorismate synthase 25 ---ky-vcebrhuj------- [E] COG0626 Cystathionine beta-lyases/cystathionine gamma-synthases 30 a--kyqvcebrhuj---linx [E] COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes (NifS family) 19 ----yqvcebrhuj------- [E] COG0031 Cysteine synthase/cystathionine beta-synthase 19 ----yqvceb-huj----inx [EM] COG0722 DAHP synthase/3-Deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase 7 --------eb-h----o---- [E] COG2195 Di- and tripeptidases 18 amt-yqvcebrhuj------- [E] COG0019 Diaminopimelate decarboxylase 15 amt--qvcebrhuj----inx [E] COG0253 Diaminopimelate epimerase 15 amt--qvcebrhuj----inx [E] COG0289 Dihydrodipicolinate reductase 21 amtk-qvcebrhuj----inx [EM] COG0329 Dihydrodipicolinate synthetase/N-acetylneuraminate lyase 16 amt-yqvcebrhuj------- [EG] COG0129 Dihydroxyacid dehydratase/phosphogluconate dehydratase 62 a--k-qvcebrhuj--olin- [E] COG0747 Dipeptide/oligopeptide/nickel ABC-type transport systems, periplasmic components 42 a--k-qvcebrhuj--o-in- [EP] COG1173 Dipeptide/oligopeptide/nickel ABC-type transport systems, permease components 47 a--k-qvcebrhujgpo-in- [EP] COG0601 Dipeptide/oligopeptide/nickel permeases 6 ---ky--c-b----------- [E] COG1506 Dipeptidyl aminopeptidases/acylaminoacyl-peptidases 4 amt---v-------------- [E] COG1037 Ferredoxin-like domain of glutamine synthase alpha chain 18 --------ebr---------- [E] COG1113 Gamma-aminobutyrate and related permeases 10 ----yqvcebrh-----l--- [E] COG0014 Gamma-glutamyl phosphate reductase (proline biosynthesis) 9 ----y--cebr-uj------- [E] COG0405 Gamma-glutamyltranspeptidase 11 ----yqvcebrh-----l--- [E] COG0263 Glutamate 5-kinase 14 amtky--ce-rh--------- [E] COG0076 Glutamate decarboxylase and related PLP-dependent proteins 18 a--ky-vcebrhuj----inx [E] COG0334 Glutamate dehydrogenase/leucine dehydrogenase 6 -------ce--huj------- [E] COG0786 Glutamate permease 11 amt-yqvcebr---------- [E] COG0067 Glutamate synthetase domain 1 15 amt-yqvcebr---------- [E] COG0069 Glutamate synthetase domain 2 14 amt-yqvcebr---------- [E] COG0070 Glutamate synthetase domain 3 5 -------ceb----------- [E] COG2066 Glutaminase 11 amt-yqvcebrh--------- [E] COG0118 Glutamine amidotransferase (HisH) 20 amtkyqvcebrhuj------x [E] COG0174 Glutamine synthase 7 -------ce--huj------- [E] COG0754 Glutathionylspermidine synthase 14 ---kyqvcebr-------in- [E] COG0509 Glycine cleavage system H protein (lipoate-binding) 8 ---kyqvcebr---------- [E] COG0404 Glycine cleavage system T protein (aminomethyltransferase) 8 ---kyqvcebr---------- [E] COG1003 Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain 8 ---kyqvcebr---------- [E] COG0403 Glycine cleavage system protein P (pyridoxal-binding), N-terminal domain 23 amtkyqvcebrhujgpolinx [E] COG0112 Glycine hydroxymethyltransferase 9 am----vce------------ [E] COG0410 High-affinity branched amino acid transport system ATPase 9 am----vce------------ [E] COG0411 High-affinity branched amino acid transport system ATPase 12 amt-yqvcebrh--------- [E] COG0141 Histidinol dehydrogenase 13 amtkyqv-ebr---------- [ER] COG1387 Histidinol phosphatase and related hydrolases of the PHP family 9 -m-----ce-rhuj------- [E] COG0241 Histidinol phosphatase and related phosphatases 17 amtkyqvcebrh--------- [E] COG0079 Histidinol-phosphate aminotransferase 4 --t-y-----rh--------- [E] COG2021 Homoserine acetyltransferase 16 amtkyqvcebrhuj------- [E] COG0460 Homoserine dehydrogenase 12 -m-kyqvcebrhuj------- [E] COG0083 Homoserine kinase 3 ------v-eb----------- [E] COG1897 Homoserine trans-succinylase 11 amt-yqvcebrh--------- [E] COG0131 Imidazoleglycerol-phosphate dehydratase 11 amt-yqvcebrh--------- [E] COG0107 Imidazoleglycerol-phosphate synthase 13 amt-yqvcebrhuj------- [E] COG0134 Indole-3-glycerol phosphate synthase 20 amtkyqvcebrh--------x [E] COG0473 Isopropylmalate dehydrogenase 27 amtkyqvcebrh--------- [E] COG0119 Isopropylmalate/homocitrate/citramalate synthases 13 amt-yqvcebrhuj------- [E] COG0059 Ketol-acid reductoisomerase (isoleucine biosynthesis) 20 amtky---ebrhuj------- [E] COG0252 L-asparaginase 10 --------ebrhuj------- [E] COG1760 L-serine deaminase 28 a-tky--cebrh--------- [E] COG0346 Lactoylglutathione lyase 15 -----q-cebrhujgp--inx [E] COG0260 Leucyl aminopeptidase 5 ------vcebr---------- [E] COG0646 Methionine synthase I (cobalamin-dependent), methyltransferase domain 8 a-t---vce-rh--------- [E] COG1410 Methionine synthase I, cobalamin-binding domain 16 amtkyqv-ebrh-------n- [E] COG0620 Methionine synthase II (cobalamin-independent) 13 a---y---ebr---------- [E] COG2030 Monoamine oxidase 3 -------c-br---------- [E] COG1231 Monoamine oxidase 3 -------c-br---------- [E] COG1834 N-Dimethylarginine dimethylaminohydrolase 3 -----q--e-r---------- [E] COG1246 N-acetylglutamate synthase and related acetyltransferases 8 am--yq-c--r-uj------- [E] COG0145 N-methylhydaintoinase A 7 -m--yq-c--r-uj------- [E] COG0146 N-methylhydaintoinase B 19 ---kyqvcebr------l--x [ER] COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases 32 a-tkyq-ceb-huj--o--nx [EHR] COG0591 Na+/proline, Na+/panthothenate symporters and related permeases 19 amt--qvcebrh--------- [E] COG0347 Nitrogen regulatory protein PII 11 ------v--b--ujgpolin- [E] COG1164 Oligoendopeptidase F 8 amt--qvc-br---------- [E] COG1364 Ornithine acetyltransferase/N-acetylglutamate synthase 16 amtkyqvcebrh---po---- [E] COG0078 Ornithine carbamoyltransferase 30 amtkyqvcebrh--------- [E] COG0160 PLP-dependent aminotransferases 52 amtkyqvcebrhuj---linx [E] COG0436 PLP-dependent aminotransferases 5 --------ebrh--------- [E] COG1168 PLP-dependent aminotransferases, MalY/PatB family 48 a-----vcebrhuj---linx [E] COG0834 Periplasmic amino acid binding proteins 3 --------eb------o---- [E] COG2113 Periplasmic binding protein of proline/glycine betaine ABC-type transport system 7 a-------ebr-uj------- [E] COG1732 Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) 10 am----vce------------ [E] COG0683 Periplasmic leucine/isoleucine/valine-binding protein 16 amtkyqvcebrhuj------- [E] COG0111 Phosphoglycerate dehydrogenase 11 amt-yqvcebrh--------- [E] COG0139 Phosphoribosyl-AMP cyclohydrolase 10 -mt-yqvcebrh--------- [E] COG0140 Phosphoribosyl-ATP pyrophosphohydrolase 12 amt--qvceb-huj----i-- [E] COG0135 Phosphoribosylanthranilate isomerase 11 amt-yqvcebrh--------- [E] COG0106 Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase 13 amtky---e-rhuj------- [E] COG0560 Phosphoserine phosphatase 4 a--k----e-r---------- [E] COG1703 Predicted GTPase (G3E family); experimentally characterized as ArgK, kinase of periplasmic Arg,Orn-binding proteins 3 -----q-ce------------ [E] COG1050 Predicted anthranilate phosphoribosyltransferase 6 a-------eb-huj------- [E] COG1296 Predicted branched-chain amino acid permease (azaleucine resistance) 4 ---------b-huj------- [E] COG1687 Predicted branched-chain amino acid permeases (azaleucine resistance) 4 a-tk----------------- [E] COG2150 Predicted regulator of amino acid metabolism (contains the ACT domain) 11 amt-yqvcebrh--------- [E] COG0077 Prephenate dehydratase 13 amt-yqvcebrhuj------- [E] COG0287 Prephenate dehydrogenase 8 ----y--cebr-uj------- [E] COG0506 Proline dehydrogenase 15 a-------ebr-uj--o---- [E] COG1174 Proline/glycine betaine ABC-type transport systems, permease components 4 --------e-r---------x [E] COG1770 Protease II (serine protease PtrB) 15 --t-yqvcebrhuj---l--- [E] COG0345 Pyrroline-5-carboxylate reductase 14 amtkyqv--br------l--- [E] COG1038 Pyruvate carboxylase, C-terminal domain/oxaloacetate decarboxylase, alpha subunit 6 a--ky--c----uj------- [E] COG1748 Saccharopine dehydrogenase and related proteins 16 --t---vcebrhujgpolin- [E] COG0520 Selenocysteine lyase 7 -mt--q--e--huj------- [E] COG1921 Selenocysteine synthase [L-seryl-tRNA(Ser) selenium transferase] 4 -m---q--e--h--------- [E] COG0709 Selenophosphate synthase 8 ------vcebrhuj------- [E] COG1045 Serine acetyltransferase 3 ---k------r---------x [E] COG1505 Serine proteases of the peptidase family S9A 13 amtkyqvc-br-uj------- [E] COG0075 Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase 17 amt-yqvcebrhuj----in- [E] COG0169 Shikimate 5-dehydrogenase 14 ----yqvcebrhuj----in- [E] COG0703 Shikimate kinase 16 ---k----eb-huj---lin- [E] COG1115 Sodium-alanine symporters 13 am-kyqv-ebr-uj------- [E] COG0421 Spermidine synthase 11 ------vce--h--gpol--- [E] COG0687 Spermidine/putrescine-binding periplasmic protein 5 ------v-eb-h--------x [E] COG2171 Tetrahydrodipicolinate N-succinyltransferase 40 amt-yqvcebrh--------- [EH] COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] 3 ----y-v-e------------ [E] COG2008 Threonine aldolase 13 ----y-vcebrh--------x [E] COG1171 Threonine dehydratase 20 ---ky-v-ebrh--------- [ER] COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases 19 amtkyqvcebrhuj------- [E] COG0498 Threonine synthase 21 a-tk-qvc-brh--------- [E] COG1305 Transglutaminase-like enzymes, putative cysteine proteases 14 amt-yqvcebrhuj----i-- [E] COG0159 Tryptophan synthase alpha chain 17 amtkyqvcebrhuj----i-- [E] COG0133 Tryptophan synthase beta chain 6 -------c-brhuj------- [E] COG0804 Urea amidohydrolase (urease) alpha subunit 6 -------c-brhuj------- [E] COG0832 Urea amidohydrolase (urease) beta subunit 6 -------c-brhuj------- [E] COG0831 Urea amidohydrolase (urease) gamma subunit 29 amtkyqvcebrhujgpolinx [E] COG0006 Xaa-Pro aminopeptidase 5 ----y--ceb-h--------- [EN] COG2091 Yeast alpha-aminoadipate reductase small subunit and related enzymes of siderophore/surfactin biosynthesis 6 ----y--ce--h--------- [E] COG0339 Zn-dependent oligopeptidases 18 a-t-yqvceb-huj---l--- [F] COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases 11 amtk-q-c--r---------- [F] COG1051 ADP-ribose pyrophosphatase 10 a---yqvcebrh--------- [F] COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful) 7 amt-----eb------o---- [F] COG1001 Adenine deaminase 22 -mtky-vcebrhujgpol--- [F] COG0503 Adenine/guanine phosphoribosyltransferases 4 ----y---e-r------l--- [F] COG1816 Adenosine deaminase 3 --------ebr---------- [F] COG2169 Adenosine deaminase 6 amtk------------o---- [F] COG1437 Adenylate cyclase, class 2 (thermophilic) 22 a--kyqvcebrhujgpolinx [F] COG0563 Adenylate kinase/yeast uridylate kinase 14 amtkyqvcebrhuj------- [F] COG0015 Adenylosuccinate lyase 14 amtkyqvcebrhuj------- [F] COG0104 Adenylosuccinate synthase 4 -mtk----------------- [F] COG2019 Archaeal adenylate kinase 6 amtk--v-e------------ [F] COG1781 Aspartate carbamoyltransferase regulatory subunit 13 amtkyqvcebr-uj------- [F] COG0540 Aspartate carbamoyltransferase, catalytic chain 20 amtkyqvcebrhuj--olinx [F] COG0504 CTP synthase (UTP-ammonia lyase) 9 ----y-v-ebrh--gpo---- [F] COG0295 Cytidine deaminase 15 -----qvcebrh--gpolinx [F] COG0283 Cytidylate kinase 6 amtk------------ol--- [F] COG1102 Cytidylate kinase 2 18 amtkyqvce---uj------- [FR] COG0402 Cytosine deaminase and related metal-dependent hydrolases 16 ----yq-cebrh------inx [F] COG0590 Cytosine deaminase-related enzymes 9 ----y---eb----------- [FH] COG1953 Cytosine/uracil/thiamine/allantoin permeases 4 ----y-------uj--o---- [F] COG1864 DNA/RNA endonuclease G, NUC1 16 amtk-q-ce-rhuj----inx [F] COG0717 Deoxycytidine deaminase 6 a--ky-v--b-------l--- [F] COG2131 Deoxycytidylate deaminase 5 ---------b----gpo---- [F] COG1428 Deoxyguanosine/deoxyadenosine kinase 11 --t--qvcebrh--gp-l--- [F] COG0274 Deoxyribose-phosphate aldolase 27 amtkyq-cebrhujgpo-inx [FGR] COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases 16 amtkyqvcebr-uj------- [F] COG0044 Dihydroorotase 5 ----y--ce---uj------- [F] COG0418 Dihydroorotase 16 amtkyqvcebrhuj------- [F] COG0167 Dihydroorotate dehydrogenase 12 ----yqvce-rhuj------x [FP] COG0248 Exopolyphosphatase 8 ----yqvcebrh--------- [F] COG0299 Folate-dependent phosphoribosylglycinamide formyltransferase PurN 6 -m-k---cebr---------- [F] COG0027 Formate-dependent phosphoribosylglycinamide formyltransferase (GAR transformylase) PurT 8 -----q-cebrhuj------- [F] COG0788 Formyltetrahydrofolate hydrolase 21 amtkyqvcebrhuj--o--n- [F] COG0518 GMP synthase - Glutamine amidotransferase domain 16 amtkyqvcebrhuj--o--n- [F] COG0519 GMP synthase - PP-ATPase domain 11 amtky-v--brh--------- [FE] COG0311 Glutamine amidotransferase (possibly involved in histidine and purine biosynthesis) 12 amtkyqvcebrh--------- [F] COG0034 Glutamine phosphoribosylpyrophosphate amidotransferase 16 ----yqvcebrhujgp--inx [F] COG0194 Guanylate kinase 8 -----qv-ebrh--gp----- [F] COG0634 Hypoxanthine-guanine phosphoribosyltransferase 38 -mtkyqvcebrhuj--o--n- [F] COG0516 IMP dehydrogenase/GMP reductase 5 ----y---e-r---------- [F] COG1957 Inosine-uridine nucleoside N-ribohydrolase 6 --------ebr---gp----- [F] COG1780 NrdI protein involved in ribonucleotide reduction 18 amtkyq-cebrhuj--olinx [F] COG0105 Nucleoside diphosphate kinase 9 --------eb-huj------- [F] COG1972 Nucleoside permease 18 ------vcebrhuj--olin- [F] COG0775 Nucleoside phosphorylase 4 ----y---e-rh--------- [F] COG1949 Oligoribonuclease (3'->5' exoribonuclease) 16 amtkyqvcebrhuj-----n- [F] COG0461 Orotate phosphoribosyltransferase 3 amt------------------ [F] COG0856 Orotate phosphoribosyltransferase homologs 13 amtkyqvceb-huj------- [F] COG0284 Orotidine-5'-phosphate decarboxylase 8 -mtk--v-e--h--------- [F] COG1328 Oxygen-sensitive ribonucleoside-triphosphate reductase NrdD 14 amtkyqvcebrhuj------- [F] COG0151 Phosphoribosylamine-glycine ligase 12 amtkyqvcebrh--------- [F] COG0150 Phosphoribosylaminoimidazol (AIR) synthetase PurM 8 ----yqvcebrh--------- [F] COG0026 Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase) PurK 13 amtkyqvcebrh--------x [F] COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase 12 amtkyqvcebrh--------- [F] COG0041 Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase PurE 12 amtkyqvcebrh--------- [F] COG0047 Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain 12 amtkyqvcebrh--------- [F] COG0046 Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain 23 amtkyqvcebrhujgpol--- [FE] COG0462 Phosphoribosylpyrophosphate synthetase 15 --t-y--ceb------olin- [F] COG1413 Phycocyanin alpha-subunit phycocyanobilin lyase and related proteins, CpcE/NblB family 17 ----yqvcebrhujgpolinx [F] COG0237 Predicted nucleotide kinase 5 amtky---------------- [F] COG1936 Predicted nucleotide kinase (related to CMP and AMP kinases) 5 amtk----------------- [F] COG1616 Predicted nucleotide kinases 11 amtky-v--brh--------- [FE] COG0214 Predicted phosphate-utilizing enzyme involved in pyridoxine/purine/histidine biosynthesis 15 amtkyqvcebr---------- [F] COG0005 Purine nucleoside phosphorylase 6 ---ky----b----------- [F] COG1457 Purine-cytosine permease and related proteins 13 --------eb-hujgp-l--- [F] COG0813 Purine-nucleoside (and uridine) phosphorylase 4 -------c-brh--------- [F] COG2065 Pyr operon attenuation protein/uracil phosphoribosyltransferase 26 a-tkyqvcebrhujgp-linx [F] COG0209 Ribonucleotide reductase alpha subunit 21 ----yq-cebrhujgp-linx [F] COG0208 Ribonucleotide reductase beta subunit 7 ------v-eb-h--gpo---- [F] COG1435 Thymidine kinase 10 am-k--v-ebr---gp----- [F] COG0213 Thymidine phosphorylase 24 amtkyqvcebrhujgpolinx [F] COG0125 Thymidylate kinase 11 amt-y---ebrh--gp----- [F] COG0207 Thymidylate synthase 5 -----q-cebr---------- [F] COG2022 Uncharacterized enzyme of thiazol biosynthesis 13 --t-yqvcebrh--gp-l--- [F] COG0035 Uracil phosphoribosyltransferase 13 ----y-vceb-h--gpol-n- [F] COG0572 Uridine kinase 20 amtk-qvcebrhujgpolinx [F] COG0528 Uridylate kinase 13 ------v-eb-h--------- [F] COG2233 Xanthine/uracil permeases 16 amtkyqvcebrh----olin- [F] COG0127 Xanthosine triphosphate pyrophosphatase, HAM1/YggV family 5 -------ce-rh--------x [F] COG0232 dGTP triphosphohydrolase 13 ----yq--ebrhuj---linx [F] COG0756 dUTPase 6 ------vcebrh--------- [H] COG1575 1,4-dihydroxy-2-naphthoate octaprenyltransferase 3 ----y---e-----------x [H] COG2227 2-Octaprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase UbiG/COQ3 14 ----y--cebr---------x [HC] COG0654 2-Octaprenyl-6-metoxyphenol hydroxylase and related FAD-dependent oxidoreductases 23 amtkyqv-ebrh-----lin- [HC] COG0543 2-Octaprenylphenol hydroxylase and related flavodoxin oxidoreductases 5 -------cebrh--------- [H] COG1165 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase 17 amt-yqvcebrhuj----in- [H] COG0108 3,4-dihydroxy-2-butanone 4-phosphate synthase 14 amtkyq-ceb--uj----inx [H] COG0163 3-octaprenyl-4-hydroxybenzoate decarboxylase 19 amtkyq-ce---uj----inx [H] COG0382 4-hydroxybenzoate octaprenyltranferase 19 ----yqvcebrhujgpolinx [H] COG0190 5,10-methylene-tetrahydrofolate dehydrogenase 16 --t-yq-cebrhujgp-linx [H] COG0212 5-formyltetrahydrofolate cyclo-ligase 15 amtk-qvceb-huj------x [H] COG0720 6-pyruvoyl-tetrahydropterin synthase 12 ----yqvcebrhuj----in- [H] COG0801 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase 5 ---k--vce-r---------- [H] COG2109 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP 3 -------ce-r---------- [H] COG2087 Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase CobU/CobP 12 -m--yq--ebrhuj-----n- [H] COG0161 Adenosylmethionine-8-amino-7-oxononanoate aminotranferase 3 amt------------------ [H] COG1731 Archaeal riboflavin synthase 8 -----qvcebr-uj------- [H] COG0853 Aspartate 1-decarboxylase 6 ---k-q-cebr---------- [H] COG0029 Aspartate oxidase 7 a------ceb----------- [H] COG0570 BioH, catalyzes some early step in biotin biosynthesis 20 -m-kyq-cebrhuj----inx [H] COG0156 Biotin biosynthesis protein BioF and related aminotransferases 17 -mt-yqvcebrhuj-----n- [H] COG0502 Biotin synthase and related enzymes 18 amtkyqvcebrhuj---linx [H] COG0340 Biotin-(acetyl-CoA carboxylase) ligase 4 amt----c------------- [H] COG1903 Cobalamin biosynthesis protein CbiD 4 amt----c------------- [H] COG2073 Cobalamin biosynthesis protein CbiG 9 amt----c---h--------- [H] COG0310 Cobalamin biosynthesis protein CbiM 16 -mt----c--r---------- [H] COG1429 Cobalamin biosynthesis protein CobN and related Mg-chelatases 8 amtk---ce-r---------- [H] COG0368 Cobalamin-5-phosphate synthase 7 amt----c--r---------- [H] COG1492 Cobyric acid synthase CbiP/CobQ 5 amt----c--r---------- [H] COG1797 Cobyrinic acid a,c-diamide synthase CobB 6 amtk---c--r---------- [H] COG1270 Cobyrinic acid a,c-diamide synthase CobB/CbiA 7 a-t-----e------------ [H] COG1541 Coenzyme F390 synthetase 4 ----y--ce-----------x [H] COG0408 Coproporphyrinogen III oxidase 22 -----qvcebrhuj--olinx [H] COG0635 Coproporphyrinogen III oxidase and related FeS oxidoreductases 3 amt------------------ [H] COG2069 Corrinoid Fe-S protein 3 amt------------------ [H] COG1456 Corrinoid/iron-sulfur protein of the CO dehydrogenase complex, large subunit 14 amt-yq-cebr-uj----inx [H] COG0113 Delta-aminolevulinic acid dehydratase 7 amt-y---e-rh--------- [H] COG0684 Demethylmenaquinone methyltransferase 15 -m---qvcebrhuj---lin- [HI] COG1154 Deoxyxylulose-5-phosphate synthase 13 -m--yq-cebrhuj-----n- [H] COG0132 Dethiobiotin synthetase 14 ----y-v-ebrh--gp--in- [H] COG0262 Dihydrofolate reductase 11 ----y--cebrhuj----in- [H] COG1539 Dihydroneopterin aldolase 19 amtkyqvcebrhuj----in- [H] COG0294 Dihydropteroate synthase 6 a------cebrh--------- [H] COG0447 Dihydroxynaphthoic acid synthase 7 ----y---eb-huj------- [H] COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1 23 a-tkyq-cebrhuj------- [H] COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 12 amtk--v-eb-h--gp-l--- [H] COG0301 Enzyme of thiamine biosynthesis (ThiI); contains a PP-loop superfamily ATPase domain and an uncharacterized conserved domain 16 ----yqvcebrhujgp-lin- [H] COG0196 FAD synthase 19 amtkyqvcebrhuj--o---- [H] COG0452 Flavoprotein involved in panthothenate metabolism 14 ----yqvcebrhuj---l--x [H] COG0285 Folylpolyglutamate synthase 11 ----yq-cebrhuj------x [H] COG0302 GTP cyclohydrolase I 16 a---yqvcebrhuj----in- [H] COG0807 GTP cyclohydrolase II 35 amtkyqvcebrhuj--olinx [H] COG0142 Geranylgeranyl pyrophosphate synthase 13 amt--q-cebr-uj----in- [H] COG0001 Glutamate-1-semialdehyde aminotransferase 12 amt--q-cebr-uj----in- [H] COG0373 Glutamyl-tRNA reductase 10 am-k---ce--h--gp----- [HJ] COG0189 Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) 8 a--ky---eb-huj------- [H] COG2145 Hydroxyethylthiazole kinase ThiM, sugar kinase family 17 amtkyqv-ebrhuj---l--- [H] COG0351 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase 7 -------cebrh--------- [HP] COG1169 Isochorismate synthase 10 ---kyqvcebr-uj------- [H] COG0413 Ketopantoate hydroxymethyltransferase 8 a--kyq--ebr---------- [H] COG1893 Ketopantoate reductase PanE/ApbA 11 ----yq-cebrh------inx [H] COG0320 Lipoate synthase 17 ---kyqvceb----gp--in- [H] COG0095 Lipoate-protein ligase A 6 ----y--ce-rh--------x [H] COG0321 Lipoate-protein ligase B 7 -----qv-e--h-----lin- [H] COG1477 Membrane-associated lipoprotein ApbE involved in thiamine biosynthesis 12 ----yqvcebr-uj----inx [H] COG2226 Methylase involved in ubiquinone/menaquinone biosynthesis UbiE/COQ5 5 -mt----c--r---------- [H] COG1240 Mg-chelatase subunit ChlD 8 amt----c--r---------- [H] COG1239 Mg-chelatase subunit ChlI 14 amtk-q-cebrhuj------- [H] COG0315 Molybdenum cofactor biosynthesis enzyme 43 amtk-qvcebrhuj------- [HR] COG0535 Molybdenum cofactor biosynthesis enzyme and related Fe-S oxidoreductases 18 amtk-q-cebrhuj------- [H] COG0303 Molybdopterin biosynthesis enzyme 13 amtk-q--ebrhuj------- [H] COG0521 Molybdopterin biosynthesis enzymes 14 amtk-q-cebrhuj------- [H] COG0314 Molybdopterin converting factor, large subunit 14 a------cebrhuj------- [H] COG1977 Molybdopterin converting factor, small subunit 12 amtk-q-cebrhuj------- [H] COG0746 Molybdopterin-guanine dinucleotide biosynthesis protein A 8 amtk-q--eb-h--------- [H] COG1763 Molybdopterin-guanine dinucleotide biosynthesis protein MobB 3 amt------------------ [H] COG1962 N5-methyl-tetrahydromethanopterin--coenzyme M methyltransferase 18 amtkyqvcebr-ujgpol--- [H] COG0171 NAD synthase 7 amtk---ce-r---------- [H] COG2038 NaMN:DMB phosphoribosyltransferase (cobalamin biosynthesis enzyme CobT) 9 amtk---ce-rh--------- [H] COG1056 Nicotinamide mononucleotide adenylyltransferase 14 amtkyqvcebrhuj------- [H] COG0157 Nicotinate-nucleotide pyrophosphorylase 14 a--kyqvcebr---gpol--- [H] COG1488 Nicotinic acid phosphoribosyltransferase 11 a-----vcebrh--------- [H] COG1441 O-succinylbenzoate synthase and related enzymes 5 --------ebrh--------- [H] COG1072 Panthothenate kinase 9 ----yqvcebr-uj------- [H] COG0414 Pantoate-beta-alanine ligase 11 -----qvcebrhuj--ol--- [H] COG0669 Phosphopantetheine adenylyltransferase 4 ----y---eb-h--------- [HE] COG1932 Phosphoserine aminotransferase 3 -m---q---b----------- [H] COG1424 Pimeloyl-CoA synthetase 9 a---yq-cebr---------x [H] COG0109 Polyprenyltransferase (cytochrome oxidase assembly factor) 14 amt-yq-cebr-uj----inx [H] COG0181 Porphobilinogen deaminase 7 amt----c--r---------- [H] COG2082 Precorrin isomerase 8 amt-yq--ebr---------- [H] COG1648 Precorrin-2 dehydrogenase 4 -mt----c--r---------- [H] COG2243 Precorrin-2 methylase CobI/CbiL 5 amt----c--r---------- [H] COG1010 Precorrin-3B methylase CobJ/CbiH 5 amt----c--r---------- [H] COG2241 Precorrin-6B methylase 1 CobL1/CbiE 6 amt----c--r---------- [H] COG2242 Precorrin-6B methylase 2 CobL2/CbiT 4 -mt----c--r---------- [H] COG2099 Precorrin-6x reductase CbiJ/CobK 12 ----yq-cebrhuj----inx [H] COG0276 Protoheme ferro-lyase (ferrochelatase) 7 a--k-q---br-------in- [H] COG1232 Protoporphyrinogen oxidase 4 ----yq-c--r---------- [H] COG2154 Pterin-4a-carbinolamine dehydratase 15 a--kyqv-ebr-uj------- [H] COG0846 Putative NaMN:DMB phosphoribosyltransferase (CobB)/SIR2 transcriptional regulator 5 -----q-ce---uj------- [H] COG0854 Pyridoxal phosphate biosynthesis protein PdxJ 6 ----y---e--h----o---- [H] COG2240 Pyridoxal/pyridoxine/pyridoxamine kinase 5 ----y--ce-rh--------- [H] COG0259 Pyridoxamine phosphate oxidase 5 -----q-ce---uj------- [H] COG1995 Pyridoxin biosynthesis protein of unknown function 12 ----yqvcebrhuj----in- [H] COG0117 Pyrimidine deaminase, riboflavin biosynthesis 17 amt-yqvcebrhuj----in- [H] COG1985 Pyrimidine reductase, riboflavin biosynthesis 11 -mtk-qvcebr-uj------- [H] COG0379 Quinolinate synthase 12 ----yqvcebrhuj----in- [H] COG0307 Riboflavin synthase alpha chain 15 amt-yqvcebrhuj----in- [H] COG0054 Riboflavin synthase beta-chain 10 amtkyqvc--r---------- [H] COG0499 S-adenosylhomocysteine hydrolase 15 ----yqvcebrhujgpol--- [H] COG0192 S-adenosylmethionine synthetase 26 amtk-qvce-r-uj----in- [HR] COG1060 Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes 10 amt--qvcebr---------- [H] COG0422 Thiamine biosynthesis protein ThiC 10 amtk-q-cebrh--------- [H] COG0611 Thiamine monophosphate kinase 13 a--kyq-cebrhuj------- [H] COG0352 Thiamine monophosphate synthase 9 ---k---ce--h-----l--- [H] COG1840 Thiamine-binding periplasmic proteins 11 ----yq-cebr-uj----inx [H] COG0407 Uroporphyrinogen-III decarboxylase 19 amt-yq-cebr---------- [H] COG0007 Uroporphyrinogen-III methylase 15 amt-yq-cebr-uj----in- [H] COG1587 Uroporphyrinogen-III synthase HemD 7 -------cebrh--------- [H] COG2228 o-Succinylbenzoate-CoA synthase 36 ----yqvcebrhuj----inx [I] COG0331 (acyl-carrier-protein) S-malonyltransferase 35 ----yqvcebrhujgpolinx [I] COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase 12 -----qvcebrhuj---lin- [I] COG0743 1-deoxy-D-xylulose 5-phosphate reductoisomerase (terpenoid biosynthesis) 3 --------ebr---------- [I] COG1021 2,3-dihydroxybenzoate-AMP ligase 19 a-------ebr---------x [I] COG1250 3-Hydroxyacyl-CoA dehydrogenase 13 --t--q-cebrh-j------- [I] COG2084 3-hydroxyisobutyrate dehydrogenase and related proteins 14 -----qvceb-huj----inx [I] COG0764 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases 52 ----yqvcebrhuj----inx [I] COG0304 3-oxoacyl-(acyl-carrier-protein) synthase I 24 amtkyq-cebrhuj--o-inx [I] COG0332 3-oxoacyl-[acyl-carrier-protein] synthase III 15 ---k-qvcebrhujgp-lin- [I] COG1211 4-diphosphocytidyl-2-methylerithritol synthase 8 ----y--ce-rh--------- [I] COG1133 ABC-type long-chain fatty acid transport system, permease component 23 a---y-vcebr------l--- [I] COG0657 Acetyl esterase 47 amtky--cebrhuj--o---x [I] COG0183 Acetyl-CoA acetyltransferases 22 a--kyqvcebrhuj----inx [I] COG0825 Acetyl-CoA carboxylase alpha subunit 21 a--k-qvcebrhuj----inx [I] COG0777 Acetyl-CoA carboxylase beta subunit 8 amt--qv-e------------ [I] COG1924 Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain) 24 ----yqvcebrhujgpolinx [I] COG0236 Acyl carrier protein 6 --------eb-h--gp----- [I] COG1182 Acyl carrier protein phosphodiesterase 58 a-------ebr---------- [I] COG1960 Acyl-CoA dehydrogenases 7 --------eb-huj----in- [I] COG1607 Acyl-CoA hydrolase 28 ----y---ebr---------- [I] COG1020 Acyl-CoA synthetases (AMP-forming)/AMP-(fatty) acid ligases I 68 a-t-y---ebrh------inx [I] COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II 5 ----y---e-rh--------- [I] COG1946 Acyl-CoA thioesterase 10 a-------ebrhuj------- [I] COG1788 Acyl-CoA:acetate CoA transferase alpha subunit 16 ----yqv-ebr-ujgpolinx [I] COG0736 Acyl-carrier protein synthase 24 a-t-yq-cebr-u-------- [I] COG0365 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases 31 amtkyqvcebrhuj---linx [I] COG0511 Biotin carboxyl carrier protein of acetyl-CoA carboxylase 28 amt-yq-cebrhuj----inx [I] COG0439 Biotin carboxylase 4 --------e-r-uj------- [I] COG2134 CDP-diacylglycerol pyrophosphatase 22 amtkyqvcebrhujgpolinx [I] COG0575 CDP-diglyceride synthetase 25 a---y-vceb-huj----inx [I] COG1502 Cardiolipin synthase, phoaphatidylserine synthase and related enzymes of the phospholipase D family 8 --------ebrhuj------- [I] COG2057 Coenzyme A transferases, subunit B 11 amtkyq-c--------ol--x [I] COG0170 Dolichol kinase 50 a---yq--ebr---------x [I] COG1024 Enoyl-CoA hydratase/carnithine racemase 11 -----q-cebrhuj----inx [I] COG0623 Enoyl-[acyl-carrier-protein] reductase (NADH) 11 -----qvceb--ujgp--in- [I] COG0416 Fatty acid/phospholipid biosynthesis enzyme 3 ----y--c------------x [I] COG1398 Fatty-acid desaturase 7 amtky-----------o---- [I] COG1257 Hydroxymethylglutaryl-CoA reductase 3 ----y---e-r---------- [I] COG1443 Isopentenyldiphosphate isomerase 13 a---yq-c--rh----ol--- [I] COG1022 Long-chain acyl-CoA synthetases (AMP-forming) 6 -----q--e--huj------- [I] COG2067 Long-chain fatty acid transport protein FadL 4 a--k----e-r---------- [I] COG2185 Methylmalonyl-CoA mutase, C-terminal domain/subunit (cobalamin-binding) 5 a--k----e-r---------- [I] COG1884 Methylmalonyl-CoA mutase, N-terminal domain/subunit 6 amtky-----------o---- [I] COG1577 Mevalonate kinase 7 a-tkyqv---r---------- [I] COG1260 Myo-inositol-1-phosphate synthase 6 -----q-ceb----------- [I] COG1842 Phage shock protein A (PspA/IM30) homologs, control membrane integrity 11 -mtk-q--eb-huj------x [I] COG1267 Phosphatidylglycerophosphatase A 37 a-tkyqvcebrhujgpolinx [I] COG0558 Phosphatidylglycerophosphate synthase 14 amt-y---ebrhuj----inx [I] COG0688 Phosphatidylserine decarboxylase 12 amt-y----br-uj---linx [I] COG1183 Phosphatidylserine synthase 6 --t-y--c-br---------- [I] COG1562 Phytoene/squalene synthetase 6 a------c--r---------x [I] COG1870 Poly-beta-hydroxyalkanoate (PHB) synthetases 7 ---------brh--------- [I] COG1835 Predicted acyltransferases 5 a-------e--huj------- [I] COG2031 Short chain fatty acids transporter 3 ----y--c-b----------- [I] COG1657 Squalene cyclase 23 amtkyqvcebrhuj--olinx [I] COG0020 Undecaprenyl pyrophosphate synthase 13 amtky--cebr---------- [R] COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) 4 -mt---v-e------------ [R] COG1151 6Fe-6S prismane cluster-containing protein 47 amt--qvcebrhujgpolinx [R] COG1136 ABC-type (unclassified) transport system, ATPase component 12 -----qvce--huj--olinx [R] COG1137 ABC-type (unclassified) transport system, ATPase component 68 amtky-vcebr-uj-pol--x [R] COG1131 ABC-type multidrug transport system, ATPase component 83 ---kyqvcebrhujgp--inx [R] COG1132 ABC-type multidrug/protein/lipid transport system, ATPase component 6 amtk----------------- [R] COG1759 ATP-utilizing enzymes of ATP-grasp superfamily (probably carboligases) 7 amt---vc------------- [R] COG1606 ATP-utilizing enzymes of the PP-loop superfamily 31 ----y--cebrhuj--olinx [R] COG0488 ATPase components of ABC transporters with duplicated ATPase domains 20 -mt-y--ce-r-uj------- [R] COG1123 ATPase components of uncharacterized ABC-type transport system, contain duplicated ATPase domain 4 amtk----------------- [R] COG1855 ATPases of the PilT family 14 amtkyqvcebrh--------- [R] COG0456 Acetyltransferases 22 -mt-y-vcebr-------in- [R] COG0110 Acetyltransferases (the isoleucine patch superfamily) 20 ---ky-vcebr---------- [R] COG0656 Aldo/keto reductases, related to diketogulonate reductase 3 ----y---e-r---------- [R] COG2015 Alkyl sulfatase and related hydrolases 18 a--kyqv-ebr-----ol--- [R] COG1335 Amidases related to nicotinamidase 14 ----y--ce-------ol--x [R] COG0666 Ankyrin repeat proteins 4 amtk----------------- [R] COG1244 Archaea-specific FeS oxidoreductases 4 amt------------------ [R] COG1099 Archaea-specific hydrolases of PHP superfamily 4 amt------------------ [R] COG1103 Archaea-specific pyridoxal phosphate-dependent enzymes 4 amtk----------------- [R] COG1938 Archaeal enzymes of ATP-grasp superfamily 4 amtk----------------- [R] COG1342 Archaeal family of DNA-binding proteins 3 am-k----------------- [R] COG1750 Archaeal serine proteases 3 --------ebr---------- [R] COG2162 Arylamine N-acetyltransferase 9 -mt---vce--h--------- [R] COG0641 Arylsulfatase regulator (Fe-S oxidoreductase) 5 amtky---------------- [R] COG1779 C4-type Zn finger family 118 amtkyqvcebrhujgpo-inx [R] COG0517 CBS domains 12 -mtk-q-cebr---------x [R] COG0663 Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily 6 ----y--ce---------inx [R] COG0400 Carboxylesterases 6 --------ebr-uj------- [R] COG1279 Conserved membrane proteins, similar to lysine exporter 22 a-tk-qvcebr---------x [R] COG1853 Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family 32 ----y--c-br---------- [R] COG2124 Cytochrome P450 family proteins 16 amtkyq-c-b----------- [R] COG0123 Deacetylases, including yeast histone deacetylase and acetoin utilization protein 165 a--kyqvcebrhuj----inx [R] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) 9 ----yq-cebr---------- [R] COG0412 Dienelactone hydrolase and related enzymes 12 a---yqv--br-uj------- [R] COG2070 Dioxygenases related to 2-nitropropane dioxygenase 7 amtky----br---------- [R] COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster 37 amtkyqvcebrhujgpolinx [R] COG0073 EMAP domain 3 ------v--b-------l--- [R] COG1647 Esterase/lipase 21 am-k-qvc-br---gpol--- [R] COG0618 Exopolyphosphatase-related proteins 6 amtky-v-------------- [R] COG1635 Flavoproteins, possibly involved in thiazole biosynthesis 45 amtkyq-c------------- [R] COG1100 GTPases 15 -----qvcebrhujgpol--x [R] COG1159 GTPases, the Era family 10 -m-k-qvcebr-------in- [R] COG2262 GTPases, the HflX family 10 amtk-qv--b----gp----- [R] COG1078 HD superfamily phosphohydrolases 9 a-t--q---br-------in- [R] COG1331 Highly conserved protein containing a thioredoxin domain 5 a-tk-qv-------------- [R] COG1350 Homologs of tryptophan synthase beta subunit 19 a---y-v-ebrh------in- [R] COG1073 Hydrolases of the alpha/beta superfamily 9 a-tky-v--br---------- [R] COG1228 Imidazolonepropionase and related amidohydrolases 13 ----y--ceb-huj--o-inx [R] COG0670 Integral membrane protein YccA, interacts with FtsH 14 amtk--vcebr------lin- [R] COG0396 Iron-regulated ABC transporter ATPase subunit SufC 10 amtk----e-r---------- [R] COG1201 Lhr-like helicases 35 -----qvceb-huj--ol--x [R] COG0845 Membrane permeases, predicted cation efflux pumps 21 amtk-qv-eb----------- [R] COG2244 Membrane protein involved in the export of O-antigen and teichoic acid, RfbX family 8 am-k--v---------ol--- [R] COG1033 Membrane proteins related to SecD/SecF 15 ---k--vcebrh--------- [R] COG1473 Metal-dependent amidohydrolases/aminoacylases 18 amtk-q-ceb------o-inx [R] COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I 9 amtk--v-------------- [R] COG1237 Metal-dependent hydrolases of the beta-lactamase superfamily II 19 amtky-vcebr-----olin- [R] COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III 3 am-k----------------- [R] COG2100 MoaA-related oxidoreductases I 5 amtk------r---------- [R] COG1964 MoaA-related oxidoreductases II 26 amtkyqvcebr-----o---- [R] COG0714 MoxR-like ATPases 10 -----q-ceb-h--------x [R] COG1566 Multidrug resistance efflux pump 17 amt-yq--ebr---------- [R] COG0655 Multimeric flavodoxin WrbA 4 a-t-----e--h--------- [R] COG2005 N-terminal domain of molybdenum-binding protein ModE 5 amt---vc------------- [R] COG1691 NCAIR mutase (PurE)-related proteins 7 --------eb-huj---l-n- [R] COG2011 Permease component of an uncharacterized ABC transporter 16 -m-k--v-eb-huj--ol--- [R] COG2252 Permeases 4 ---------b-h----o---- [R] COG1783 Phage terminase large subunit 3 --------e-r----p----- [R] COG1735 Phosphotriesterase homology protein PHP/1bf6A (activity unknown) 8 --t----c--r---------- [R] COG1233 Phytoene dehydrogenase and related proteins 3 amt------------------ [R] COG2232 Predicted ATP-dependent carboligases related to biotin carboxylase 3 amt------------------ [R] COG1821 Predicted ATP-utilizing enzymes of ATP-grasp superfamily 15 amtk-qvce-r---------- [R] COG0433 Predicted ATPase 4 ----y---e-r---------x [R] COG1485 Predicted ATPase 13 amtk-q-ceb-huj------x [R] COG0603 Predicted ATPase (PP-loop superfamily), confers aluminum resistance 19 ----yqvcebrhujgpo-inx [R] COG0482 Predicted ATPase of the PP-family 11 --t--qvce-rhuj--o---- [R] COG0606 Predicted ATPases 6 -m-k--------uj------- [R] COG1106 Predicted ATPases 7 amtky---------------- [R] COG2102 Predicted ATPases of PP-loop superfamily 21 -mtk--v-------------- [R] COG1672 Predicted ATPases of the AAA superfamily 38 amtkyqvcebrhujgpolinx [R] COG0037 Predicted ATPases of the PP-loop superamily 3 -mtk----------------- [R] COG2117 Predicted ATPases of the PP-loop superfamily 6 amtk-qv-------------- [R] COG1618 Predicted ATPases or kinases 3 a-tk----------------- [R] COG1661 Predicted DNA-binding proteins with PD1-like DNA-binding motif 4 -mt---v-------------- [R] COG2000 Predicted Fe-S proteins 13 -----qvcebrhuj---l--- [R] COG0820 Predicted Fe-S-cluster redox enzyme 5 -mt--q----r---------- [R] COG2229 Predicted GTP-binding proteins, apparently inactivated GTPases 23 amtkyqvcebrhujgpolinx [R] COG0012 Predicted GTPase 5 amtky---------------- [R] COG1084 Predicted GTPase 6 amtky---------------- [R] COG1163 Predicted GTPase 17 ----yqvcebrhujgpolinx [R] COG0536 Predicted GTPase 3 am-k----------------- [R] COG1341 Predicted GTPase or GTP-binding protein 14 -m-ky-vc-b----gpo---- [R] COG1161 Predicted GTPases 11 -----qvcebrh--gpo---- [R] COG1162 Predicted GTPases 14 am-kyqv-eb-hujgp----x [R] COG0218 Predicted GTPases 17 ----yqvcebrhujgpolinx [R] COG1160 Predicted GTPases 12 ----y--cebr-uj------- [R] COG0699 Predicted GTPases (dynamin-related) 16 ----yqvceb-hujgpolinx [R] COG0486 Predicted GTPases, ThdF family 6 amtk----------------- [R] COG1407 Predicted ICC-like phosphoesterases 6 ----yq-ceb----------- [R] COG0385 Predicted Na+-dependent transporter 4 --------eb-h----o---- [R] COG1823 Predicted Na+-dicarboxylate symporter 4 amtk----------------- [R] COG1782 Predicted RNA binding protein (KH domain) 4 --------eb-h-----l--- [R] COG2183 Predicted RNA binding protein, contains S1 domain 13 -----qvc-br-uj--olin- [R] COG1837 Predicted RNA-binding protein (KH domain) 7 amtk----eb-h--------- [R] COG1534 Predicted RNA-binding protein containing KH domain 3 amt------------------ [R] COG1532 Predicted RNA-binding proteins 5 amtky---------------- [R] COG1537 Predicted RNA-binding proteins 6 ------vc-br-----ol--- [R] COG1847 Predicted RNA-binding proteins, Jag family 10 a--kyqv-ebr---------- [R] COG1611 Predicted Rossmann fold nucleotide-binding protein 16 ----yqvcebrhujgp-linx [R] COG0220 Predicted S-adenosylmethionine-dependent methyltransferase 12 -m-k-qv-eb-h------in- [R] COG1092 Predicted SAM-dependent methyltransferases 5 am-k---ce------------ [R] COG0434 Predicted TIM-barrel enzyme 28 amt-yqvcebrhuj--olinx [R] COG0042 Predicted TIM-barrel enzymes, possibly dehydrogenases, nifR3 family 12 amtky--c------------- [R] COG1236 Predicted Zn-dependent hydrolases (beta-lactamase superfamily) 15 amtky-vcebr---------- [R] COG2220 Predicted Zn-dependent hydrolases of the beta-lactamase fold 27 ----yqvcebrhuj--o---x [R] COG0612 Predicted Zn-dependent peptidases 5 ----y-----------olin- [R] COG1026 Predicted Zn-dependent peptidases, insulinase-like 5 am-k-q--------------- [R] COG1913 Predicted Zn-dependent proteases 26 amtk-qvce-rh--------- [R] COG0312 Predicted Zn-dependent proteases and their inactivated homologs 85 amtkyqvcebr-uj----in- [R] COG0454 Predicted acetyltransferases 20 a---yq-c-br---gpo---- [R] COG1075 Predicted acetyltransferases and hydrolases with the alpha/beta hydrolase fold 3 -------ce-r---------- [R] COG2153 Predicted acyltransferases 34 a-tkyqvcebr-uj------- [R] COG0388 Predicted amidohydrolase 9 -----qvcebrh----ol--- [R] COG1040 Predicted amidophosphoribosyltransferases 7 ----yq-ce-rh--------x [R] COG0354 Predicted aminomethyltransferase related to GcvT 9 --t-yq--ebr---------- [R] COG2234 Predicted aminopeptidases 4 -------ceb-h--------- [R] COG2103 Predicted aminotransferase, homolog of eukaryotic glucokinase regulator 4 amtk----------------- [R] COG1608 Predicted archaeal kinases 4 amtk----------------- [R] COG1829 Predicted archaeal kinases of the sugar kinase superfamily 5 amtk----------------- [R] COG1907 Predicted archaeal sugar kinases 14 amtkyq--eb-huj------- [R] COG0615 Predicted cytidylyltransferases 10 a-----vce-r-ujgp----- [R] COG0579 Predicted dehydrogenase 30 --tkyqvceb--uj------- [R] COG0673 Predicted dehydrogenases and related proteins 4 amt------------------ [R] COG2085 Predicted dinucleotide-binding enzymes 4 amt---v-------------- [R] COG1712 Predicted dinucleotide-utilizing enzyme 10 ----yqvcebrhuj------- [R] COG0325 Predicted enzyme with a TIM-barrel fold 5 ----y--cebr---------- [R] COG0384 Predicted epimerase, PhzC/PhzF homolog 14 --t--q-cebrhuj---l--- [R] COG0824 Predicted esterase 5 ----y--ce--h--------- [R] COG0627 Predicted esterase 7 ----y--cebr---gp----- [R] COG0431 Predicted flavoprotein 4 -------ceb-h--------- [R] COG2081 Predicted flavoproteins, YhiN family 9 -mt-y--ce-rh--------- [R] COG0121 Predicted glutamine amidotransferase 4 --------e-r---------x [R] COG2071 Predicted glutamine amidotransferases 11 a-tk---ce-r---------- [R] COG1216 Predicted glycosyltransferases 11 amtk-qv-e------------ [R] COG1203 Predicted helicases 8 -mtkyq--------------- [R] COG1204 Predicted helicases 8 amtk-qv---r---------- [R] COG1353 Predicted hydrolase of the HD superfamily (permuted catalytic motifs) 5 ----y--ce------------ [R] COG0429 Predicted hydrolase of the alpha/beta-hydrolase fold 7 a--ky---e---uj------- [R] COG1896 Predicted hydrolases of HD superfamily 26 -mtkyqvcebrhujgpolinx [R] COG0084 Predicted hydrolases of PHP superfamily 37 a-tky-vcebrh--gpolin- [R] COG0561 Predicted hydrolases of the HAD superfamily 22 -mtky-v-eb---j--o---- [R] COG1011 Predicted hydrolases of the HAD superfamily 56 a---yq-cebr-ujgp----x [R] COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) 16 amtk-qvce-----gp----- [R] COG0392 Predicted integral membrane protein 17 amtk--v-ebr------lin- [R] COG1321 Predicted iron-dependent transcription repressor 23 amtkyqvcebrhujgpol--x [R] COG0061 Predicted kinase 3 -----q-c--r---------- [R] COG0645 Predicted kinase 6 ------v--br---gp----- [R] COG1461 Predicted kinase related to hydroxyacetone kinase 23 amtk--vcebr------lin- [R] COG0719 Predicted membrane components of an uncharacterized iron-regulated ABC-type transporter SufB 5 --t-y---e------------ [R] COG1584 Predicted membrane protein 8 ----y---ebr-----ol--- [R] COG1272 Predicted membrane proteins, hemolysin III homologs 12 --------e--huj------x [R] COG2194 Predicted membrane-associated, metal-dependent hydrolase 8 amtk----eb----------- [R] COG1988 Predicted membrane-bound metal-dependent hydrolases 4 ---k--vc--r---------- [R] COG2251 Predicted metal-binding domain (associated with helicases in Pyrococcus and Mtub) 5 a--k---c-b----------- [R] COG2140 Predicted metal-binding proteins 7 -----qvcebrh--------- [R] COG1399 Predicted metal-binding, possibly nucleic acid-binding protein 8 amtk-qv-------------- [R] COG1468 Predicted metal-binding, possibly nucleic acid-binding protein similar to domains found in Superfamily I helicases 8 a-tk----e---uj------- [R] COG1451 Predicted metal-dependent hydrolase 17 -mtk--vc-br-ujgp----x [R] COG0595 Predicted metal-dependent hydrolase 3 3 am-k----------------- [R] COG2248 Predicted metal-dependent hydrolases 6 ---k-qv--br---------- [R] COG1574 Predicted metal-dependent hydrolases 4 amtk----------------- [R] COG1831 Predicted metal-dependent hydrolases of the urease superfamily 11 amt--qvce--h--------- [R] COG0613 Predicted metal-dependent phosphoesterases (PHP family) 5 am-k-q--------------- [R] COG1568 Predicted methyltransferases 7 ----y--cebr---------- [R] COG2040 Predicted methyltransferases 16 -----qvcebrhujgpolinx [R] COG0313 Predicted methyltransferases 3 ------v--br---------- [R] COG1623 Predicted nucleic-acid-binding protein (contains the HHH domain) 5 -------cebrh--------- [R] COG1090 Predicted nucleoside-diphosphate sugar epimerases (SulA family) 3 amt------------------ [R] COG1548 Predicted nucleotide-binding enzyme 5 ------v--b--uj---l--- [R] COG1564 Predicted nucleotide-binding protein 14 -----qvcebrhuj--olinx [R] COG0802 Predicted nucleotide-binding protein, YjeE family 8 a--ky-vcebr---------- [R] COG1058 Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA 5 amtky---------------- [R] COG1019 Predicted nucleotidyltransferase 26 amtk-qv----h--------- [R] COG1708 Predicted nucleotidyltransferases 14 ----yqvcebr-ujgpol--- [R] COG1057 Predicted nucleotidyltransferases 11 am----vc------------- [R] COG1669 Predicted nucleotidyltransferases 22 amtkyq-cebrhuj--o-in- [R] COG0665 Predicted oxidoreductases 4 --t---vc------------- [R] COG1453 Predicted oxidoreductases of the aldo/keto reductase family 32 amtk-qvcebrhuj--ol--x [R] COG0628 Predicted permease 38 amt--qvcebrhuj--olinx [R] COG0577 Predicted permease 4 ---------b-huj------- [R] COG2056 Predicted permease 21 ------vce--huj--olinx [R] COG0795 Predicted permeases 3 -------ceb----------- [R] COG0700 Predicted permeases 34 amtk-qvceb-huj------- [R] COG0730 Predicted permeases 10 amt--qvcebr---------- [R] COG0701 Predicted permeases 12 -mt-yqvceb----------x [R] COG0679 Predicted permeases 64 a-tkyqvceb-huj---linx [R] COG0697 Predicted permeases 6 amt--q--------------- [R] COG2044 Predicted peroxiredoxins 17 ---ky-vcebrh------in- [R] COG0637 Predicted phosphatase/phosphohexomutase 26 -mtkyq-cebrhuj---l--x [R] COG0671 Predicted phosphatases 26 a-tkyq-cebrhuj--ol--- [R] COG0546 Predicted phosphatases 5 amtk-----b----------- [R] COG1646 Predicted phosphate-binding enzymes, TIM-barrel fold 18 amtky-v-eb----gp-l--- [R] COG0622 Predicted phosphoesterase 5 amtk-q--------------- [R] COG2129 Predicted phosphoesterases, related to the Icc protein 4 -m---q------------in- [R] COG1768 Predicted phosphohydrolases 11 --t--q--ebr-uj----in- [R] COG1408 Predicted phosphohydrolases 14 a-tkyq-ce-rh------in- [R] COG1409 Predicted phosphohydrolases, Icc family 10 a--ky-------uj--ol--- [R] COG2236 Predicted phosphoribosyltransferases 6 -----q----r-uj------- [R] COG1926 Predicted phosphoribosyltransferases 6 am-k----------------- [R] COG1800 Predicted transglutaminase-like proteases 14 --t-y--ce-r---------x [R] COG0661 Predicted unusual protein kinase 32 amtkyqvcebrhujgpol--- [R] COG0534 Probable cation efflux pump (multidrug resistance protein) 10 ----yq-cebr-uj------- [R] COG0523 Putative GTPases (G3E family) 3 ----y---eb----------- [R] COG2130 Putative NADP-dependent oxidoreductases 11 --------eb-huj------- [R] COG2249 Putative NADPH-quinone reductase, YabF family (modulator of drug activity B) 7 -mtk--v-ebr---------- [R] COG2151 Putative aromatic ring hydroxylating enzyme 14 -----qvcebrhujgp-lin- [R] COG0245 Putative enzyme of deoxyxylulose pathway (terpenoid biosynthesis), YgbB family 22 am-kyq-cebr---gpol--- [R] COG0693 Putative intracellular protease/amidase 10 ----yq--ebrh--------- [R] COG2132 Putative multicopper oxidases 15 ----yqv-ebr------l--x [R] COG1752 Putative phosphoesterases, homologs of neuropathy target esterase 5 amtky---------------- [R] COG1245 RNase L inhibitor homolog, predicted ATPase 258 amtkyqvcebrhujgpolinx [R] COG0500 SAM-dependent methyltransferases 3 -mt----c------------- [R] COG2144 Selenophosphate synthetase-related proteins 11 ----y--cebrhuj------- [R] COG0300 Short-chain dehydrogenases of various substrate specificities 15 am-k-q---b-huj---lin- [R] COG0733 Sodium-dependent transporters (SNF family) 3 -mtk----------------- [R] COG1202 Specific archaeal helicases 7 -------ce-rh------in- [R] COG2166 SufE protein probably involved in Fe-S center assembly 15 amt-yqvce--huj---lin- [R] COG0496 Survival protein SurE, predicted acid phosphatase 24 ----y---e--huj--o---- [R] COG0790 TPR repeat proteins 146 amtkyqvceb-huj--olinx [R] COG0457 TPR-repeat-containing proteins 10 -----q-ce-rhuj------x [R] COG1127 Uncharacterized ABC-type transport system, ATPase component 21 a--k--v--b----gpol--- [R] COG1079 Uncharacterized ABC-type transport systems, permease components 10 a-tk--vc-b-------li-x [R] COG1268 Uncharacterized ACR, BioY family 6 -m---qv-eb-h--------- [R] COG1923 Uncharacterized ACR, host factor I protein Hfq 8 amt---vc--rh--------- [R] COG1878 Uncharacterized ACR, predicted metal-dependent hydrolases 11 amt--q----r---------- [R] COG2018 Uncharacterized ACR; distantly related to eukaryotic homeotic protein bithoraxoid 12 -m-k--v---rh--------- [R] COG1373 Uncharacterized ATPases of the AAA superfamily 3 -mtk----------------- [R] COG1365 Uncharacterized ATPases of the PP-loop superfamily 3 am-k----------------- [R] COG2108 Uncharacterized ArCR related to pyruvate formate-lyase activating enzyme 4 -------c--r-----o---x [R] COG1754 Uncharacterized C-terminal domain of topoisomerase IA 39 -----qvcebrhuj--olinx [R] COG1253 Uncharacterized CBS domain-containing proteins 7 amtk-qv-------------- [R] COG1313 Uncharacterized Fe-S protein PflX, homolog of pyruvate formate lyase activating proteins 5 -m---qv-eb----------- [R] COG1242 Uncharacterized FeS oxidoreductases 5 --t-----ebr---------- [R] COG2068 Uncharacterized MobA-related protein 47 amtkyqvce-r---gpol--- [R] COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases 3 am-k----------------- [R] COG1645 Uncharacterized Zn-finger containing protein 3 amt------------------ [R] COG1685 Uncharacterized archaeal kinases distantly related to homoserine/aspartokinases 3 amt------------------ [R] COG2054 Uncharacterized archaeal kinases related to aspartokinases, uridylate kinases 5 a----q--ebr---------- [R] COG2041 Uncharacterized enzymes, related to nitrate reductase 16 amtk-qv-eb--ujgpol--- [R] COG1418 Uncharacterized hydrolases of the HD superfamily 16 am-kyqvcebrh-----l--- [R] COG0705 Uncharacterized membrane protein (homolog of Drosophila rhomboid) 4 a-----v-eb----------- [R] COG1811 Uncharacterized membrane protein, possible Na+ channel or pump 12 ------vce-rhuj--olinx [R] COG0728 Uncharacterized membrane protein, putative virulence factor MviN 19 am-k--vceb-h--gpo-in- [R] COG0600 Uncharacterized permeases 11 -----qvcebr-ujgp----- [R] COG1546 Uncharacterized protein CinA/YgaD (competence- and mitomycin-induced) 14 a--k-q--ebrhuj------- [R] COG2050 Uncharacterized protein PaaI, possibly involved in aromatic compounds catabolism 6 ------v-ebrh-----l--- [R] COG2137 Uncharacterized protein RecX 6 ----yq---b----------x [R] COG1999 Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems 6 --t-y---ebr---------- [R] COG2079 Uncharacterized protein involved in propionate catabolism 5 a-t------b--uj------- [R] COG1942 Uncharacterized protein, 4-oxalocrotonate tautomerase homolog 6 -mt---vc--r---------- [R] COG1402 Uncharacterized protein, putative amidase 5 -----q--e--huj------- [R] COG1778 Uncharacterized proteins of HAD superfamily, CMP-Neu5Ac homologs 6 amtky---------------- [R] COG1412 Uncharacterized proteins of PilT N-term./Vapc superfamily 6 a--ky-v-------------- [R] COG1524 Uncharacterized proteins of the AP superfamily 4 amtk----------------- [R] COG2047 Uncharacterized proteins of the ATP-grasp superfamily 7 ----y---e-rh--------- [R] COG1248 Uncharacterized proteins with the alpha/beta hydrolase fold 3 ------vc-b----------- [R] COG2179 Uncharacterized proteins, HAD superfamily 4 ---k----eb-h--------- [R] COG1540 Uncharacterized proteins, homologs of lactam utilization protein B 8 ---k---ce--h-----l--- [R] COG1178 Uncharacterized transport system, permease component 16 amt--q-ce-rhuj------- [R] COG0378 Urease/hydrogenase-associated predicted GTPases 11 amtk-q-ce---uj------- [R] COG0375 Zn finger protein HypA/HybF (possibly regulating hydrogenase expression) 16 ----y--cebr-uj------- [R] COG1064 Zn-dependent alcohol dehydrogenases 52 amtkyqvcebrhuj------- [R] COG0491 Zn-dependent hydrolases, including glyoxylases 16 a---y---ebr----p----- [R] COG1065 Zn-dependent oxidoreductases 14 amt--qvc-br-uj------- [R] COG1994 Zn-dependent proteases 3 amt------------------ [R] COG2158 Zn-finger-like domain 8 -----q----r-uj--olin- [R] COG1579 Zn-ribbon protein, possibly nucleic acid-binding 4 amtk----------------- [R] COG2260 Zn-ribbon proteins 6 a--k-qv-e-r---------- [S] COG2110 An uncharacterized domain related to the C-terminal domain of histone macroH2A1 10 a-t---vceb-h--------- [S] COG1280 Conserved membrane proteins, YahN/YigJ family 18 ----yqvcebrhujgpolinx [S] COG0706 Inner membrane proteins, SpoIIIJ family 10 a-----vce--h-----l--- [S] COG1593 Integral membrane protein, possible transporter 15 am-k-q--eb-------lin- [S] COG2095 Integral membrane proteins of the MarC family 6 -mtk----------------- [S] COG1822 Predicted archaeal membrane protein 34 a-tk--vcebr-uj------- [S] COG0842 Predicted integral membrane protein 12 ------vceb-huj--olin- [S] COG0762 Predicted integral membrane protein, YggT family 8 --------ebrh--------- [S] COG2259 Predicted membrane protein 3 a--k--v-------------- [S] COG1470 Predicted membrane protein 4 -------c----uj------x [S] COG1981 Predicted membrane protein 32 -----q-ce-rhuj------x [S] COG1463 Predicted membrane protein 3 -------c-br---------- [S] COG1950 Predicted membrane protein 17 --t--qvc-br-----o-in- [S] COG1266 Predicted membrane protein 4 --t---v---------ol--- [S] COG2035 Predicted membrane protein 3 am-k----------------- [S] COG2237 Predicted membrane protein 3 ----y--c--r---------- [S] COG2119 Predicted membrane protein 3 --t-----eb----------- [S] COG1971 Predicted membrane protein 4 -----q-ce-r---------- [S] COG2149 Predicted membrane protein 13 a--k--vc-b-----pol--- [S] COG1277 Predicted membrane protein 4 amtk----------------- [S] COG1784 Predicted membrane protein 4 -m------e--h-----l--- [S] COG2215 Predicted membrane protein 4 am-------b----------- [S] COG1557 Predicted membrane protein 3 --t------br---------- [S] COG1511 Predicted membrane protein 8 am-k--v-------------- [S] COG1361 Predicted membrane protein 11 -----qvceb-hujgp----- [S] COG0344 Predicted membrane protein, YgiH/UPF0078 family 5 ---k----eb-h--------- [S] COG1380 Predicted membrane protein, YohJ family 6 ---k----eb-h--------- [S] COG1346 Predicted membrane protein, YohK family 5 --------ebr---------- [S] COG2261 Predicted membrane proteins 5 amtk----------------- [S] COG1967 Predicted membrane proteins 8 -----q-c----uj------x [S] COG1538 Putative outer membrane protein 5 amtk-q--------------- [S] COG1458 Uncharacterized ACR 3 -----qv---r---------- [S] COG1507 Uncharacterized ACR 3 a-tk----------------- [S] COG1504 Uncharacterized ACR 4 amt-----e------------ [S] COG1986 Uncharacterized ACR 15 amtk--v-------------- [S] COG1433 Uncharacterized ACR 5 amtk-q--------------- [S] COG1980 Uncharacterized ACR 4 ------vce--------l--- [S] COG1512 Uncharacterized ACR 6 -----qvce--h--------- [S] COG1434 Uncharacterized ACR 7 a--ky---e--h--------- [S] COG1444 Uncharacterized ACR 6 ---ky---ebrh--------- [S] COG1984 Uncharacterized ACR 5 amtky---------------- [S] COG1500 Uncharacterized ACR 6 amt-------r-------in- [S] COG1478 Uncharacterized ACR 5 a-t---vc------------- [S] COG2006 Uncharacterized ACR 6 amtk--v--b----------- [S] COG1469 Uncharacterized ACR 4 amt--q--------------- [S] COG1465 Uncharacterized ACR 6 a-t---vc------------- [S] COG2013 Uncharacterized ACR 3 a--k--v-------------- [S] COG1483 Uncharacterized ACR 3 -mtk----------------- [S] COG2014 Uncharacterized ACR 5 amtky---------------- [S] COG1990 Uncharacterized ACR 5 -mtk----------------- [S] COG1991 Uncharacterized ACR 5 -mtk--v-------------- [S] COG1992 Uncharacterized ACR 6 -m-k-qv---r---------- [S] COG1993 Uncharacterized ACR 7 ----yqv-ebrh--------- [S] COG1490 Uncharacterized ACR 5 a-t--qv-------------- [S] COG1336 Uncharacterized ACR 5 a-tky---------------- [S] COG2106 Uncharacterized ACR 6 a----q------uj----in- [S] COG2107 Uncharacterized ACR 5 amtky---------------- [S] COG2118 Uncharacterized ACR 6 -------ce-r-uj------- [S] COG2127 Uncharacterized ACR 3 --t-------------ol--- [S] COG1306 Uncharacterized ACR 6 amt---v---r---------- [S] COG1343 Uncharacterized ACR 4 amtk----------------- [S] COG1339 Uncharacterized ACR 5 -mtk--v---r---------- [S] COG1337 Uncharacterized ACR 5 -mtk--v---r---------- [S] COG1332 Uncharacterized ACR 4 a--k-----br---------- [S] COG2096 Uncharacterized ACR 3 --------ebr---------- [S] COG2128 Uncharacterized ACR 15 am-k---c--r-uj------- [S] COG0727 Uncharacterized ACR 4 a----q---b----------- [S] COG2210 Uncharacterized ACR 6 am-k--v-------------- [S] COG2250 Uncharacterized ACR 4 ---k------r--j------- [S] COG2253 Uncharacterized ACR 3 am-k----------------- [S] COG2254 Uncharacterized ACR 3 a-t---v-------------- [S] COG2164 Uncharacterized ACR 6 ----y---ebr---------- [S] COG2135 Uncharacterized ACR 6 amtky---------------- [S] COG2136 Uncharacterized ACR 7 a----qvc--r-------in- [S] COG1259 Uncharacterized ACR 5 ---k-qv-------------- [S] COG2152 Uncharacterized ACR 5 -------ce-r---------- [S] COG2161 Uncharacterized ACR 7 amtkyqv-------------- [S] COG2078 Uncharacterized ACR 3 -mtk----------------- [S] COG2029 Uncharacterized ACR 9 amt------------------ [S] COG1417 Uncharacterized ACR 3 a-t--q--------------- [S] COG1416 Uncharacterized ACR 4 a-tk----------------- [S] COG1415 Uncharacterized ACR 3 am-k----------------- [S] COG2028 Uncharacterized ACR 17 amtk-q-c----uj------- [S] COG1432 Uncharacterized ACR 3 am---q--------------- [S] COG1431 Uncharacterized ACR 7 -mtk--vc--------ol--- [S] COG1430 Uncharacterized ACR 6 a----q------uj----in- [S] COG1427 Uncharacterized ACR 4 -mtk--v-------------- [S] COG1421 Uncharacterized ACR 3 -mt-y---------------- [S] COG2042 Uncharacterized ACR 6 amtk-qv-------------- [S] COG1371 Uncharacterized ACR 5 amtky---------------- [S] COG1369 Uncharacterized ACR 3 a----qv-------------- [S] COG1367 Uncharacterized ACR 8 amtkyqv-------------- [S] COG1355 Uncharacterized ACR 11 am-k-qvc-br---gp-l--- [S] COG1354 Uncharacterized ACR 5 -mtk-----b----------- [S] COG1379 Uncharacterized ACR 5 -mt---vc-b----------- [S] COG2045 Uncharacterized ACR 6 ---ky---ebrh--------- [S] COG2049 Uncharacterized ACR 12 amtk--v--b-h------in- [S] COG1392 Uncharacterized ACR 9 a--k--vc-br---gp-l--- [S] COG1386 Uncharacterized ACR 3 amt------------------ [S] COG2061 Uncharacterized ACR 14 -m-k--v-----uj------- [S] COG1479 Uncharacterized ACR 12 amtk-qvcebr---------x [S] COG1585 Uncharacterized ACR 6 am-k-qv--b----------- [S] COG1586 Uncharacterized ACR 5 am-ky---------------- [S] COG1590 Uncharacterized ACR 4 amt-------r---------- [S] COG1920 Uncharacterized ACR 4 amt----c------------- [S] COG1915 Uncharacterized ACR 12 -mt--q-c------------- [S] COG1719 Uncharacterized ACR 9 a-t---vc-----j------- [S] COG1598 Uncharacterized ACR 10 amtk-qv-------------- [S] COG1583 Uncharacterized ACR 4 a-tk----------------- [S] COG1572 Uncharacterized ACR 3 -mt------b----------- [S] COG1809 Uncharacterized ACR 6 ------v-eb-huj------- [S] COG1576 Uncharacterized ACR 3 am-k----------------- [S] COG1935 Uncharacterized ACR 4 --tk-qv-------------- [S] COG1688 Uncharacterized ACR 13 a--k-qvc-br-----o---- [S] COG1721 Uncharacterized ACR 6 amtk-qv-------------- [S] COG1578 Uncharacterized ACR 5 amtk-q--------------- [S] COG1812 Uncharacterized ACR 7 am-k-qv-----uj------- [S] COG1912 Uncharacterized ACR 5 amt---vc------------- [S] COG1641 Uncharacterized ACR 5 ---k-qv-eb----------- [S] COG1832 Uncharacterized ACR 5 am-k--v-------------- [S] COG1895 Uncharacterized ACR 9 --tk-qv--b----------- [S] COG1633 Uncharacterized ACR 4 -mtk------r---------- [S] COG1637 Uncharacterized ACR 3 --tk-q--------------- [S] COG1700 Uncharacterized ACR 5 a-tk--v---r---------- [S] COG1839 Uncharacterized ACR 5 amtk--v-------------- [S] COG1833 Uncharacterized ACR 13 am-k-q-c-b----gpolin- [S] COG1624 Uncharacterized ACR 6 a-tk----------------- [S] COG1602 Uncharacterized ACR 3 a----qv-------------- [S] COG1604 Uncharacterized ACR 3 a--k--v-------------- [S] COG1906 Uncharacterized ACR 4 a------c--r---------- [S] COG1615 Uncharacterized ACR 6 amt----c------------- [S] COG1900 Uncharacterized ACR 4 --t---v--b----------- [S] COG1827 Uncharacterized ACR 3 am-k----------------- [S] COG1901 Uncharacterized ACR 4 amtk----------------- [S] COG1617 Uncharacterized ACR 7 a--k-qv---r------l--- [S] COG1656 Uncharacterized ACR 4 ---k---c--r------l--- [S] COG1543 Uncharacterized ACR 17 amtk------r---------- [S] COG1545 Uncharacterized ACR 6 am-k----------------- [S] COG1753 Uncharacterized ACR 4 amt---v-------------- [S] COG1751 Uncharacterized ACR 6 --------e-rh------inx [S] COG1678 Uncharacterized ACR 3 amt------------------ [S] COG1873 Uncharacterized ACR 4 --t--qv--b----------- [S] COG1683 Uncharacterized ACR 3 -m---qv-------------- [S] COG1542 Uncharacterized ACR 3 -m-k-q--------------- [S] COG1517 Uncharacterized ACR 3 am-k----------------- [S] COG1865 Uncharacterized ACR 9 amtk-qv---r---------- [S] COG1518 Uncharacterized ACR 3 a----qv-------------- [S] COG1769 Uncharacterized ACR 6 ---k-qv-e------------ [S] COG1765 Uncharacterized ACR 8 am-k--vc--r---------- [S] COG1533 Uncharacterized ACR 5 a--ky---e------------ [S] COG1859 Uncharacterized ACR 4 am-----c------------- [S] COG1808 Uncharacterized ACR 7 -mtk--vc------------x [S] COG1563 Uncharacterized ACR 5 -----q-c----uj------x [S] COG1565 Uncharacterized ACR 7 a--k-qv-eb----------- [S] COG1801 Uncharacterized ACR 5 -mtk--v---r---------- [S] COG1567 Uncharacterized ACR 5 a--k--v-------------- [S] COG1743 Uncharacterized ACR 3 -m-k-q--------------- [S] COG1851 Uncharacterized ACR 5 -mt-----e-rh--------- [S] COG1944 Uncharacterized ACR 8 amtk--------------in- [S] COG1945 Uncharacterized ACR 14 -----qvcebrhuj--olinx [S] COG0799 Uncharacterized ACR (homolog of plant Iojap proteins) 7 -m---qvcebr---------- [S] COG0390 Uncharacterized ACR (membrane protein) 4 ----y--ce------------ [S] COG0401 Uncharacterized ACR, Blt101 homolog 4 --tk-q--------------- [S] COG1642 Uncharacterized ACR, DevR homolog 15 ------vcebr---------- [S] COG1376 Uncharacterized ACR, ErfK family 16 ----yq-cebrh--------x [S] COG0316 Uncharacterized ACR, HesB/YadR/YfhF family 3 -m----v----------l--- [S] COG1704 Uncharacterized ACR, LemA family 10 amtk--vce-r---------- [S] COG0393 Uncharacterized ACR, MJ1170 family 19 a--k-qvcebrh----olin- [S] COG1694 Uncharacterized ACR, MazG family 4 am-ky---------------- [S] COG1756 Uncharacterized ACR, Mra1/C2f family 7 a-tk-q-c--r---------- [S] COG1310 Uncharacterized ACR, PAD1/JAB1-related 6 ----yqv--b-------l--- [S] COG1774 Uncharacterized ACR, PSP1 homologs 6 amtk------------ol--- [S] COG1916 Uncharacterized ACR, PrgY homolog (pheromone shutdown protein) 13 am-k---ce-r---------- [S] COG2026 Uncharacterized ACR, RelE homolog 10 amtk-qv-e-r---------- [S] COG1690 Uncharacterized ACR, RtcB/UPF0027 family 12 ---k-qvc--r-uj--olinx [S] COG1351 Uncharacterized ACR, THY1 family 6 ----y-------------inx [S] COG1723 Uncharacterized ACR, YDL001w/YagE family 8 amtk--v-e--h--------- [S] COG1720 Uncharacterized ACR, YaeB/UPF0066 family 15 amtky---ebrhuj--olin- [S] COG0327 Uncharacterized ACR, YbgI/Acr family 16 a-tkyq--ebr-uj----in- [S] COG1881 Uncharacterized ACR, YbhB family 11 amt-yqvcebr---------- [S] COG0391 Uncharacterized ACR, YbhK/UPF0052 family 6 -------ceb--------inx [S] COG1054 Uncharacterized ACR, YceA family 11 -----qvcebrhuj---li-- [S] COG1947 Uncharacterized ACR, YchB/YabH family 3 ----y--ce------------ [S] COG0397 Uncharacterized ACR, YdiU/UPF0061 family 9 ----y--cebr---------- [S] COG0398 Uncharacterized ACR, YdjX/UPF0043 family 19 ----yqvcebrhujgpolinx [S] COG0217 Uncharacterized ACR, YebC family 7 amt--qvc-b----------- [S] COG1828 Uncharacterized ACR, YexA/UPF0062 family 10 -----q-cebrh----o-inx [S] COG1496 Uncharacterized ACR, YfiH family 11 amtkyq--e--huj------- [S] COG0585 Uncharacterized ACR, YgbO/UPF0024 family 7 amt-----e---------inx [S] COG1872 Uncharacterized ACR, YggU family 14 amtk----eb--uj------- [S] COG0864 Uncharacterized ACR, YhhG family 11 a-----v-eb-h----o-in- [S] COG1738 Uncharacterized ACR, YhhQ family 12 -----qvcebrhuj--o-in- [S] COG0759 Uncharacterized ACR, YidD family 15 amtkyq-ceb--uj----inx [S] COG0043 Uncharacterized ACR, YigC family 9 ----y-v-eb-huj--o---- [S] COG1739 Uncharacterized ACR, YigZ/UPF0029 family 14 amtk-qvcebr---------- [S] COG0432 Uncharacterized ACR, YjbQ/UPF0047 family 13 amtkyqvce-r-uj------- [S] COG0062 Uncharacterized ACR, YjeF/UPF0031 family 8 -m---qv-eb-h-----l--- [S] COG1509 Uncharacterized ACR, YjeK family (putative lysine 2,3-aminomutase) 5 a-------eb--uj------- [S] COG1556 Uncharacterized ACR, YkgG family 4 -m-k----eb----------- [S] COG2105 Uncharacterized ACR, YkqA family 4 -mt---v--b----------- [S] COG1323 Uncharacterized ACR, YlbM family 8 amt----c-br---------- [S] COG2138 Uncharacterized ACR, YlnE family 7 -------cebr---------- [S] COG1359 Uncharacterized ACR, YneC family 10 amtkyqvc-br---------- [S] COG0011 Uncharacterized ACR, YqgV/UPF0045 family 9 --t--qvcebr-----o---- [S] COG1968 Uncharacterized ACR, bacitracin resistance protein BacA 3 ---k-qv-------------- [S] COG1856 Uncharacterized ACR, biotin synthetase homolog 4 ----yqv--b----------- [S] COG1791 Uncharacterized ACR, double-stranded beta-helix domain 8 --tk-qvc--r-uj------- [S] COG1917 Uncharacterized ACR, double-stranded beta-helix domain 14 amt---vc-brh--------- [S] COG0599 Uncharacterized ACR, homolog of gamma-carboxymuconolactone decarboxylase subunit 38 amtk-qvcebrhuj--ol--x [S] COG0668 Uncharacterized ACR, integral membrane protein, YjeP/UPF0003 family 5 --t----cebr---------- [S] COG2104 Uncharacterized ACR, possibly involved in thiamine biosynthesis 4 ---k---c--r---------- [S] COG2159 Uncharacterized ACR, putative hydrolase 5 amtk----------------- [S] COG1673 Uncharacterized ArCR 4 amtk----------------- [S] COG1860 Uncharacterized ArCR 3 amt------------------ [S] COG1707 Uncharacterized ArCR 4 amtk----------------- [S] COG1786 Uncharacterized ArCR 3 amt------------------ [S] COG1693 Uncharacterized ArCR 3 amt------------------ [S] COG1667 Uncharacterized ArCR 3 am-k----------------- [S] COG1772 Uncharacterized ArCR 3 -mtk----------------- [S] COG1698 Uncharacterized ArCR 3 amt------------------ [S] COG2122 Uncharacterized ArCR 4 amtk----------------- [S] COG1701 Uncharacterized ArCR 3 -mtk----------------- [S] COG1710 Uncharacterized ArCR 3 a-tk----------------- [S] COG1689 Uncharacterized ArCR 3 amt------------------ [S] COG1852 Uncharacterized ArCR 4 amtk----------------- [S] COG1849 Uncharacterized ArCR 3 -mtk----------------- [S] COG1817 Uncharacterized ArCR 8 amt------------------ [S] COG1810 Uncharacterized ArCR 3 -mtk----------------- [S] COG1255 Uncharacterized ArCR 3 amt------------------ [S] COG1790 Uncharacterized ArCR 4 am-k----------------- [S] COG1857 Uncharacterized ArCR 3 -mtk----------------- [S] COG1844 Uncharacterized ArCR 3 a-tk----------------- [S] COG1711 Uncharacterized ArCR 4 amtk----------------- [S] COG1679 Uncharacterized ArCR 3 -mtk----------------- [S] COG1771 Uncharacterized ArCR 3 amt------------------ [S] COG2098 Uncharacterized ArCR 5 amtk----------------- [S] COG1581 Uncharacterized ArCR 4 amtk----------------- [S] COG1931 Uncharacterized ArCR 5 amtk----------------- [S] COG1630 Uncharacterized ArCR 3 am-k----------------- [S] COG1650 Uncharacterized ArCR 3 a-tk----------------- [S] COG1892 Uncharacterized ArCR 4 amtk----------------- [S] COG1382 Uncharacterized ArCR 3 -mtk----------------- [S] COG1627 Uncharacterized ArCR 4 amtk----------------- [S] COG2090 Uncharacterized ArCR 9 amt------------------ [S] COG2043 Uncharacterized ArCR 4 amtk----------------- [S] COG1325 Uncharacterized ArCR 4 amtk----------------- [S] COG1628 Uncharacterized ArCR 4 amtk----------------- [S] COG2083 Uncharacterized ArCR 4 amtk----------------- [S] COG1634 Uncharacterized ArCR 3 amt------------------ [S] COG1891 Uncharacterized ArCR 3 amt------------------ [S] COG1531 Uncharacterized ArCR 4 amtk----------------- [S] COG1303 Uncharacterized ArCR 4 amtk----------------- [S] COG1909 Uncharacterized ArCR 4 amtk----------------- [S] COG1888 Uncharacterized ArCR 4 amtk----------------- [S] COG1571 Uncharacterized ArCR 3 amt------------------ [S] COG1665 Uncharacterized ArCR 4 amtk----------------- [S] COG1460 Uncharacterized ArCR 3 -mtk----------------- [S] COG1356 Uncharacterized ArCR 3 am-k----------------- [S] COG1885 Uncharacterized ArCR 5 amt------------------ [S] COG1745 Uncharacterized ArCR; probably metal-binding, MJ1205/UPF0058 family 3 -------ce-r---------- [S] COG2170 Uncharacterized BCR 5 -----qv--b-------l--- [S] COG1639 Uncharacterized BCR 6 -----qv----huj------x [S] COG1636 Uncharacterized BCR 14 -----qvcebrhuj--ol--x [S] COG1385 Uncharacterized BCR 10 ------------uj--olin- [S] COG1664 Uncharacterized BCR 3 ------vc-b----------- [S] COG1939 Uncharacterized BCR 3 -----q--e-----------x [S] COG1729 Uncharacterized BCR 5 -----q-c-b----gp----- [S] COG1466 Uncharacterized BCR 5 ------v--br---gp----- [S] COG1481 Uncharacterized BCR 5 ------vc-b------ol--- [S] COG1963 Uncharacterized BCR 5 --------ebr---------- [S] COG1975 Uncharacterized BCR 3 -----qv--b----------- [S] COG1978 Uncharacterized BCR 8 -------cebr---------- [S] COG1937 Uncharacterized BCR 3 ------vc-b----------- [S] COG2052 Uncharacterized BCR 6 ------vc-b----gp-l--- [S] COG1713 Uncharacterized BCR 7 -------c--r-------in- [S] COG1716 Uncharacterized BCR 3 -----q-c--r---------- [S] COG2187 Uncharacterized BCR 6 -------cebrh--------- [S] COG1929 Uncharacterized BCR 3 ------vc-----j------- [S] COG1724 Uncharacterized BCR 4 -----q-ce--h--------- [S] COG1934 Uncharacterized BCR 6 ------v--b--------in- [S] COG1302 Uncharacterized BCR 5 -----qv-----uj------- [S] COG2143 Uncharacterized BCR 5 --------eb------ol--- [S] COG1652 Uncharacterized BCR 3 ------v---------ol--- [S] COG1655 Uncharacterized BCR 8 ------vcebrh------in- [S] COG1327 Uncharacterized BCR 4 -----q------uj------x [S] COG2121 Uncharacterized BCR 4 -------ceb----------- [S] COG1649 Uncharacterized BCR 8 ------v--b--uj--ol--- [S] COG1699 Uncharacterized BCR 4 ---------b--------inx [S] COG2155 Uncharacterized BCR 3 ------v---------ol--- [S] COG1315 Uncharacterized BCR 7 -------c-br-----o-in- [S] COG1262 Uncharacterized BCR 4 -------c---huj------- [S] COG0748 Uncharacterized BCR 17 -----q-ce-rhuj------x [S] COG0767 Uncharacterized BCR (predicted membrane protein), YrbE family 16 -----qvcebrhujgpolinx [S] COG0319 Uncharacterized BCR (putative metal-binding protein) 5 ------v--b--uj---l--- [S] COG2257 Uncharacterized BCR homologous to the cytoplasmic domain of flagellar protein FhlB 15 -----qvcebrhujgpolin- [S] COG0658 Uncharacterized BCR, ComEC family 4 ----------------olin- [S] COG1747 Uncharacterized BCR, N-terminal domain of the transcription elongation factor GreA (in T. pallidum, a separate protein). 4 ------v--b------ol--- [S] COG1728 Uncharacterized BCR, YaaR family 4 --------eb------ol--- [S] COG1671 Uncharacterized BCR, YaiI/YqxD family 4 --------ebrh--------- [S] COG1666 Uncharacterized BCR, YajQ family 14 ------vcebrhujgpo-inx [S] COG0718 Uncharacterized BCR, YbaB family 10 -----q--ebrhuj--ol--x [S] COG1559 Uncharacterized BCR, YceG family 3 --------eb----------x [S] COG1806 Uncharacterized BCR, YdiA family 12 -----qvcebrhuj--ol--x [S] COG0779 Uncharacterized BCR, YhbC family 4 --------ebrh--------- [S] COG1660 Uncharacterized BCR, YhbJ/UPF0042 family 4 -------ce-r---------- [S] COG1741 Uncharacterized BCR, YhhW family 5 --------e--h------inx [S] COG1322 Uncharacterized BCR, YigN family 4 --------ebrh--------- [S] COG2258 Uncharacterized BCR, YiiM family 15 ------v--b----gpo-in- [S] COG1284 Uncharacterized BCR, YitT family 12 -----qvcebrh--------x [S] COG1959 Uncharacterized BCR, YjeB/RRF2 family 10 -----qvceb-huj------x [S] COG0780 Uncharacterized BCR, YkvM family 8 --------ebrh--gp-l--x [S] COG2001 Uncharacterized BCR, YllB/UPF0040 family 3 -------c-br---------- [S] COG1799 Uncharacterized BCR, YlmF family 3 ------v--br---------- [S] COG1550 Uncharacterized BCR, YlxP family 6 -----q---b----gpo---- [S] COG1692 Uncharacterized BCR, YmdB family 4 -------cebr---------- [S] COG1742 Uncharacterized BCR, YnfA/UPF0060 family 3 ---------brh--------- [S] COG1755 Uncharacterized BCR, YpbQ family 3 -----q-c-b----------- [S] COG1547 Uncharacterized BCR, YpuF family 6 -----qvceb-h--------- [S] COG1281 Uncharacterized BCR, YrfI family 6 a------ce-rh--------- [S] COG0857 Uncharacterized N-terminal domain of phosphotransacetylases 4 amtk----------------- [S] COG1326 Uncharacterized archaeal Zn-finger family 3 a-tk----------------- [S] COG1340 Uncharacterized archaeal coiled-coil domain 3 amt------------------ [S] COG1795 Uncharacterized archaeal domain 5 amtk----------------- [S] COG2034 Uncharacterized archaeal membrane protein 7 amtkyq--------------- [S] COG1730 Uncharacterized coiled-coil protein 3 am-k----------------- [S] COG1955 Uncharacterized family of membrane proteins 22 -------cebr------l--x [S] COG1357 Uncharacterized low-complexity proteins 6 -m---q--e--h--------- [S] COG1238 Uncharacterized membrane protein 5 ------vc-b-------l-n- [S] COG1480 Uncharacterized membrane protein 4 --------eb-h----o---- [S] COG1288 Uncharacterized membrane protein 5 a--k---c-b----------- [S] COG2246 Uncharacterized membrane protein 3 --------eb-------l--- [S] COG1283 Uncharacterized membrane protein 3 -m-k--v-------------- [S] COG2245 Uncharacterized membrane protein 5 ---ky-----rh--------- [S] COG1297 Uncharacterized membrane protein 9 amtk---c-br---------- [S] COG1300 Uncharacterized membrane protein 4 amtk----------------- [S] COG1422 Uncharacterized membrane protein 7 ------vce--h------in- [S] COG1805 Uncharacterized membrane protein, RnfD family 7 -----q-cebrh-----l--- [S] COG1285 Uncharacterized membrane protein, SapB family 5 -------ceb-h--------- [S] COG1289 Uncharacterized membrane protein, YhfK family 11 amtky---------------- [S] COG1287 Uncharacterized membrane protein, required for N-linked glycosylation 8 --------eb-huj--ol--x [S] COG1286 Uncharacterized membrane protein, required for colicin V production 11 --t----c-brh--------x [S] COG1714 Uncharacterized membrane protein/domain 8 amtk----------------- [S] COG2064 Uncharacterized membrane proteins 5 amtk---c------------- [S] COG1836 Uncharacterized membrane proteins 7 amtky-v-------------- [S] COG1814 Uncharacterized membrane proteins 19 -------cebrhuj--ol--- [S] COG0586 Uncharacterized membrane-associated protein, DedA family 3 a--------br---------- [S] COG1273 Uncharacterized protein 6 amtky---------------- [S] COG1818 Uncharacterized protein sharing a conserved domain with thiamine biosynthesis protein ThiI 9 ------v--br---gp----- [S] COG1307 Uncharacterized protein, DegV family 4 ----y-v--br---------- [S] COG1610 Uncharacterized protein, YqeY family 3 -----qv---r---------- [S] COG1659 Uncharacterized protein, linocin/CFP29 homolog 14 amtk--v-ebr-----ol--x [S] COG1520 Uncharacterized proteins of WD40-like repeat family 10 ----y-vcebr---------- [S] COG1597 Uncharacterized proteins, BmrU family 6 amtk----e--h--------- [S] COG1767 Uncharacterized proteins, CitG homologs 5 ---k-----br---------- [S] COG2120 Uncharacterized proteins, LmbE homologs 14 am-k---c--rh--------- [S] COG1487 Uncharacterized proteins, VapC family 9 ------v-eb-h----olinx [S] COG1426 Uncharacterized proteins, YfgA family 6 -------ceb-------l--x [S] COG1619 Uncharacterized proteins, homologs of microcin C7 resistance protein MccF 12 -----qv-ebrhuj--o-inx [S] COG1862 Uncharacterized secreted proteins, YajC family 7 -----qv-eb-h----o---- [S] COG1561 Uncharacterized stress-induced protein, YicC family