Analyses of Cytochrome c (cyc) Pseudogenes in Human Genome

We have identified over 49 cytochrome c (cyc) pseudogenes in the August 2001 freeze of the human genome draft.
Relevant data and results can be found here.
 
 

Publications

• Zhang et al. Gene (2003, in press)

Resources

• Human cyc gene in GenBank
• FASTA files containing the amino acid sequences, CDS DNA sequences, and mRNA sequences of selected eukaryotes.
• Alignment of amino acid sequences and underlining nucleotide sequences of cyc from selected eukaryotes
• Comparative analysis of cyc by Banchi et al. and Grossman et al.
• Previously identified human cyc pseudogenes in GenBank (some are redundant).

Results

• Annotation file (Excel, .txt), which lists the location, length et al. on each cyc pseudogene.
• Predicted amino acid sequences of cyc pseudogenes and alignment ( .txt , Excel).
• Nucleotide sequence of protein coding sequence (CDS) of  cyc pseudogenes and alignment.
• Alignment of 5' UTR and 3' UTR sequence of human cyc pseudogenes.
• Chromosome mapping of the cyc pseudogenes.
• A phylogenetic tree of the pseudogenes constructed using MEGA2.
• Amino acid sequence alignment of the pseudogenes with disablement highlighted.
• Classification of cyc pseudogenes based on sequences at 9 codon positions.
• Comparison of codon sequences between pseudogene HCP9 and rodent testis-specific cyc genes.
• A flowchart of pseudogene discovery procedures.