Enzyme Structures Database
[-] signifies that there are no PDB entries for the given enzyme subclass 

E.C.1.-.-.- Oxidoreductases.
The oxidoreductases catalyse oxido-reductions. The substrate oxidised is regarded as an hydrogen or
electron donor. 

The E.C. classification for these enzymes classifies them firstly by the donor group that undergoes
oxidation, then by the acceptor, and lastly by the enzyme. 

The recommended name for these enzymes is dehydrogenase. An alternative name is reductase. The
name oxidase is only used where O(2) is the acceptor. 

There are 604 PDB entries in enzyme class E.C.1.-.-.- 


E.C.1.1.-.- Acting on the CH-OH group of donors.

There are 146 PDB entries in enzyme class E.C.1.1.-.- 

     E.C.1.1.1.- With NAD(+) or NADP(+) as acceptor. [ 124 PDB entries ] 
     E.C.1.1.2.- With a cytochrome as acceptor. [ 4 PDB entries ] 
     E.C.1.1.3.- With oxygen as acceptor. [ 15 PDB entries ] 
     E.C.1.1.4.- With a disulfide as acceptor. [-] 
     E.C.1.1.5.- With a quinone or similar compound as acceptor. [-] 
     E.C.1.1.99.- With other acceptors. [ 3 PDB entries ] 


E.C.1.2.-.- Acting on the aldehyde or oxo group of donors.

There are 27 PDB entries in enzyme class E.C.1.2.-.- 

     E.C.1.2.1.- With NAD(+) or NADP(+) as acceptor. [ 25 PDB entries ] 
     E.C.1.2.2.- With a cytochrome as acceptor. [-] 
     E.C.1.2.3.- With oxygen as acceptor. [ 2 PDB entries ] 
     E.C.1.2.4.- With a disulfide as acceptor. [-] 
     E.C.1.2.7.- With an IRON-sulfur protein as acceptor. [-] 
     E.C.1.2.99.- With other acceptors. [-] 


E.C.1.3.-.- Acting on the CH-CH group of donors.

There are 19 PDB entries in enzyme class E.C.1.3.-.- 

     E.C.1.3.1.- With NAD(+) or NADP(+) as acceptor. [ 12 PDB entries ] 
     E.C.1.3.2.- With a cytochrome as acceptor. [-] 
     E.C.1.3.3.- With oxygen as acceptor. [ 1 PDB entry ] 
     E.C.1.3.5.- With a quinone or related compound as acceptor. [-] 
     E.C.1.3.7.- With an IRON-sulfur protein as acceptor. [-] 
     E.C.1.3.99.- With other acceptors. [ 6 PDB entries ] 


E.C.1.4.-.- Acting on the CH-NH(2) group of donors.

There are 20 PDB entries in enzyme class E.C.1.4.-.- 

     E.C.1.4.1.- With NAD(+) or NADP(+) as acceptor. [ 4 PDB entries ] 
     E.C.1.4.2.- With a cytochrome as acceptor. [-] 
     E.C.1.4.3.- With oxygen as acceptor. [ 8 PDB entries ] 
     E.C.1.4.4.- With a disulfide as acceptor. [ 2 PDB entries ] 
     E.C.1.4.7.- With an IRON-sulfur protein as acceptor. [-] 
     E.C.1.4.99.- With other acceptors. [ 6 PDB entries ] 


E.C.1.5.-.- Acting on the CH-NH group of donors.

There are 68 PDB entries in enzyme class E.C.1.5.-.- 

     E.C.1.5.1.- With NAD(+) or NADP(+) as acceptor. [ 67 PDB entries ] 
     E.C.1.5.3.- With oxygen as acceptor. [-] 
     E.C.1.5.4.- With a disulfide as acceptor. [-] 
     E.C.1.5.5.- With a quinone or similar compound as acceptor. [-] 
     E.C.1.5.99.- With other acceptors. [ 1 PDB entry ] 


E.C.1.6.-.- Acting on nadh or nadph.

There are 51 PDB entries in enzyme class E.C.1.6.-.- 

     E.C.1.6.1.- With NAD(+) or NADP(+) as acceptor. [-] 
     E.C.1.6.2.- With a cytochrome as acceptor. [ 5 PDB entries ] 
     E.C.1.6.4.- With a disulfide as acceptor. [ 31 PDB entries ] 
     E.C.1.6.5.- With a quinone or similar compound as acceptor. [ 2 PDB entries ] 
     E.C.1.6.6.- With a nitrogenous group as acceptor. [ 4 PDB entries ] 
     E.C.1.6.7.- (not defined) [-] 
     E.C.1.6.8.- With a flavin as acceptor. [ 1 PDB entry ] 
     E.C.1.6.99.- With other acceptors. [ 8 PDB entries ] 


E.C.1.7.-.- Acting on other nitrogenous compounds as donors.

There are 13 PDB entries in enzyme class E.C.1.7.-.- 

     E.C.1.7.2.- With a cytochrome as acceptor. [-] 
     E.C.1.7.3.- With oxygen as acceptor. [-] 
     E.C.1.7.7.- With an IRON-sulfur protein as acceptor. [-] 
     E.C.1.7.99.- With other acceptors. [ 13 PDB entries ] 


E.C.1.8.-.- Acting on a sulfur group of donors.

There are 18 PDB entries in enzyme class E.C.1.8.-.- 

     E.C.1.8.1.- With NAD(+) or NADP(+) as acceptor. [ 18 PDB entries ] 
     E.C.1.8.2.- With a cytochrome as acceptor. [-] 
     E.C.1.8.3.- With oxygen as acceptor. [-] 
     E.C.1.8.4.- With a disulfide as acceptor. [-] 
     E.C.1.8.5.- With a quinone or similar compound as acceptor. [-] 
     E.C.1.8.6.- (not defined) [-] 
     E.C.1.8.7.- With an IRON-sulfur protein as acceptor. [-] 
     E.C.1.8.99.- With other acceptors. [-] 


E.C.1.9.-.- Acting on a heme group of donors.

There are 3 PDB entries in enzyme class E.C.1.9.-.- 

     E.C.1.9.3.- With oxygen as acceptor. [ 3 PDB entries ] 
     E.C.1.9.6.- With a nitrogenous group as acceptor. [-] 
     E.C.1.9.99.- With other acceptors. [-] 


E.C.1.10.-.- Acting on diphenols and related substances as donors.

There are 5 PDB entries in enzyme class E.C.1.10.-.- 

     E.C.1.10.1.- With NAD(+) or NADP(+) as acceptor. [-] 
     E.C.1.10.2.- With a cytochrome as acceptor. [ 1 PDB entry ] 
     E.C.1.10.3.- With oxygen as acceptor. [ 4 PDB entries ] 
     E.C.1.10.99.- With other acceptors. [-] 


E.C.1.11.-.- Acting on a peroxide as acceptor (peroxidases).

There are 89 PDB entries in enzyme class E.C.1.11.-.- 

     E.C.1.11.1.- (not defined) [ 89 PDB entries ] 


E.C.1.12.-.- Acting on hydrogen as donor.

There are no PDB entries in enzyme class E.C.1.12.-.- 

     E.C.1.12.1.- With NAD(+) or NADP(+) as acceptor. [-] 
     E.C.1.12.2.- With a cytochrome as acceptor. [-] 
     E.C.1.12.7.- (not defined) [-] 
     E.C.1.12.99.- With other acceptors. [-] 


E.C.1.13.-.- Acting on single donors with incorporation of molecular oxygen.

There are 17 PDB entries in enzyme class E.C.1.13.-.- 

     E.C.1.13.11.- With incorporation of two atoms of oxygen. [ 16 PDB entries ] 
     E.C.1.13.12.- With incorporation of one atom of oxygen. [ 1 PDB entry ] 
     E.C.1.13.99.- Miscellaneous (requires further characterization). [-] 


E.C.1.14.-.- Acting on paired donors with incorporation of molecular
oxygen.

There are 67 PDB entries in enzyme class E.C.1.14.-.- 

     E.C.1.14.11.- With 2-oxoglutarate as one donor, and incorporation of one atom [ 1 PDB entry ] 
     E.C.1.14.12.- With nadh or nadph as one donor, and incorporation of two atoms [-] 
     E.C.1.14.13.- With nadh or nadph as one donor, and incorporation of one atom [ 26 PDB entries ] 
     E.C.1.14.14.- With reduced flavin or flavoprotein as one donor, and [ 8 PDB entries ] 
     E.C.1.14.15.- With a reduced IRON-sulfur protein as one donor, and [ 21 PDB entries ] 
     E.C.1.14.16.- With reduced pteridine as one donor, and incorporation of one [-] 
     E.C.1.14.17.- With ascorbate as one donor, and incorporation of one atom of [-] 
     E.C.1.14.18.- With another compound as one donor, and incorporation of one [-] 
     E.C.1.14.99.- Miscellaneous (requires further characterization). [ 11 PDB entries ] 


E.C.1.15.-.- Acting on superoxide radicals as acceptor.

There are 32 PDB entries in enzyme class E.C.1.15.-.- 

     E.C.1.15.1.- (not defined) [ 32 PDB entries ] 


E.C.1.16.-.- Oxidizing metal ions.

There is 1 PDB entry in enzyme class E.C.1.16.-.- 

     E.C.1.16.1.- With NAD(+) or NADP(+) as acceptor. [-] 
     E.C.1.16.3.- With oxygen as acceptor. [ 1 PDB entry ] 


E.C.1.17.-.- Acting on -CH(2) groups.

There are 12 PDB entries in enzyme class E.C.1.17.-.- 

     E.C.1.17.1.- With NAD(+) or NADP(+) as acceptor. [-] 
     E.C.1.17.3.- With oxygen as acceptor. [-] 
     E.C.1.17.4.- With a disulfide as acceptor. [ 12 PDB entries ] 
     E.C.1.17.99.- With other acceptors. [-] 


E.C.1.18.-.- Acting on reduced ferredoxin as donor.

There are 16 PDB entries in enzyme class E.C.1.18.-.- 

     E.C.1.18.1.- With NAD(+) or NADP(+) as acceptor. [ 9 PDB entries ] 
     E.C.1.18.3.- (not defined) [-] 
     E.C.1.18.6.- With dinitrogen as acceptor. [ 6 PDB entries ] 
     E.C.1.18.99.- With H(+) as acceptor. [ 1 PDB entry ] 


E.C.1.19.-.- Acting on reduced flavodoxin as donor.

There are no PDB entries in enzyme class E.C.1.19.-.- 

     E.C.1.19.6.- With dinitrogen as acceptor. [-] 


E.C.1.97.-.- Other oxidoreductases.

There are no PDB entries in enzyme class E.C.1.97.-.- 

     E.C.1.97.1.- (not defined) [-] 


E.C.2.-.-.- Transferases.


Transferases are enzymes that transfer a group (eg a methyl or glycosyl group) from one compound
(which is generally regarded as the donor) to another compound (generally regarded as the acceptor). 

The E.C. classification for these enzymes classifies them firstly by the donor group, then by the acceptor,
and lastly by the enzyme. 

The recommended names are normally formed as: acceptor-group transferase, or donor-group
transferase. in many cases the donor is a cofactor (coenzyme) charged with the group to be transferred. 

There are 818 PDB entries in enzyme class E.C.2.-.-.- 

E.C.2.1.-.- Transferring ONE-carbon groups.

There are 97 PDB entries in enzyme class E.C.2.1.-.- 

     E.C.2.1.1.- Methyltransferases. [ 66 PDB entries ] 
     E.C.2.1.2.- Hydroxymethyl-, formyl- and related transferases. [ 5 PDB entries ] 
     E.C.2.1.3.- Carboxyl- and carbamoyltransferases. [ 22 PDB entries ] 
     E.C.2.1.4.- Amidinotransferases. [ 4 PDB entries ] 


E.C.2.2.-.- Transferring aldehyde or ketone residues.

There are 7 PDB entries in enzyme class E.C.2.2.-.- 

     E.C.2.2.1.- (not defined) [ 7 PDB entries ] 


E.C.2.3.-.- Acyltransferases.

There are 35 PDB entries in enzyme class E.C.2.3.-.- 

     E.C.2.3.1.- Acyltransferases. [ 33 PDB entries ] 
     E.C.2.3.2.- Aminoacyltransferases. [ 2 PDB entries ] 


E.C.2.4.-.- Glycosyltransferases.

There are 78 PDB entries in enzyme class E.C.2.4.-.- 

     E.C.2.4.1.- Hexosyltransferases. [ 50 PDB entries ] 
     E.C.2.4.2.- Pentosyltransferases. [ 28 PDB entries ] 
     E.C.2.4.99.- Transferring other glycosyl groups. [-] 


E.C.2.5.-.- Transferring alkyl or aryl groups, other than methyl groups.

There are 57 PDB entries in enzyme class E.C.2.5.-.- 

     E.C.2.5.1.- (not defined) [ 57 PDB entries ] 


E.C.2.6.-.- Transferring nitrogenous groups.

There are 53 PDB entries in enzyme class E.C.2.6.-.- 

     E.C.2.6.1.- Transaminases (aminotransferases). [ 53 PDB entries ] 
     E.C.2.6.2.- (not defined) [-] 
     E.C.2.6.3.- Oximinotransferases. [-] 
     E.C.2.6.99.- Transferring other nitrogenous groups. [-] 


E.C.2.7.-.- Transferring phosphorous-containing groups.

There are 486 PDB entries in enzyme class E.C.2.7.-.- 

     E.C.2.7.1.- Phosphotransferases with an alcohol group as acceptor. [ 125 PDB entries ] 
     E.C.2.7.2.- Phosphotransferases with a carboxyl group as acceptor. [ 5 PDB entries ] 
     E.C.2.7.3.- Phosphotransferases with a nitrogenous group as acceptor. [ 9 PDB entries ] 
     E.C.2.7.4.- Phosphotransferases with a phosphate group as acceptor. [ 37 PDB entries ] 
     E.C.2.7.5.- (not defined) [-] 
     E.C.2.7.6.- Diphosphotransferases. [-] 
     E.C.2.7.7.- Nucleotidyltransferases. [ 309 PDB entries ] 
     E.C.2.7.8.- Transferases for other substituted phosphate groups. [-] 
     E.C.2.7.9.- Phosphotransferases with paired acceptors. [ 1 PDB entry ] 


E.C.2.8.-.- Transferring sulfur-containing groups.

There are 5 PDB entries in enzyme class E.C.2.8.-.- 

     E.C.2.8.1.- Sulfurtransferases. [ 5 PDB entries ] 
     E.C.2.8.2.- Sulfotransferases. [-] 
     E.C.2.8.3.- COA-Transferases. [-] 


E.C.2.9.-.- Transferring selenium-containing groups.

There are no PDB entries in enzyme class E.C.2.9.-.- 

     E.C.2.9.1.- (not defined) [-] 


E.C.3.-.-.- Hydrolases.
E.C.3.-.-.- Hydrolases.

The hydrolases catalyse the hydrolytic cleavage of C-O, C-N, C-C and some other bonds, including
phosphoric anhydride bonds. 

The E.C. classification for these enzymes generally classifies them firstly by the nature of the bond
hydrolysed, then by the nature of the substrate, and lastly by the enzyme. 

Although the systematic name always includes hydrolase, the recommended name is, in many cases,
formed by the name of the substrate with the suffix -ase. It is understood that the name of the substrate
with this suffix means a hydrolytic enzyme. 

There are 2013 PDB entries in enzyme class E.C.3.-.-.- 

E.C.3.1.-.- Acting on ester bonds.

There are 510 PDB entries in enzyme class E.C.3.1.-.- 

     E.C.3.1.1.- Carboxylic ester hydrolases. [ 85 PDB entries ] 
     E.C.3.1.2.- Thiolester hydrolases. [ 1 PDB entry ] 
     E.C.3.1.3.- Phosphoric monoester hydrolases. [ 88 PDB entries ] 
     E.C.3.1.4.- Phosphoric diester hydrolases. [ 30 PDB entries ] 
     E.C.3.1.5.- Triphosphoric monoester hydrolases. [-] 
     E.C.3.1.6.- Sulfuric ester hydrolases. [ 1 PDB entry ] 
     E.C.3.1.7.- Diphosphoric monoester hydrolases. [-] 
     E.C.3.1.8.- Phosphoric triester hydrolases. [-] 
     E.C.3.1.11.- Exodeoxyribonucleases producing 5'-phosphomonoesters. [ 2 PDB entries ] 
     E.C.3.1.13.- Exoribonucleases producing 5'-phosphomonoesters. [-] 
     E.C.3.1.14.- Exoribonucleases producing other than 5'-phosphomonoesters. [-] 
     E.C.3.1.15.- Exonucleases active with either RIBO- or deoxyribonucleic acid [-] 
     E.C.3.1.16.- Exonucleases active with either RIBO- or deoxyribonucleic acid [-] 
     E.C.3.1.21.- Endodeoxyribonucleases producing 5'-phosphomonoesters. [ 18 PDB entries ] 
     E.C.3.1.22.- Endodeoxyribonucleases producing other than 5'-phosphomonoesters. [ 1 PDB
     entry ] 
     E.C.3.1.25.- SITE-Specific endodeoxyribonucleases specific for altered bases. [ 6 PDB entries ] 
     E.C.3.1.26.- Endoribonucleases producing 5'-phosphomonoesters. [ 133 PDB entries ] 
     E.C.3.1.27.- Endoribonucleases producing other than 5'-phosphomonoesters. [ 110 PDB entries ]
     E.C.3.1.30.- Endonucleases active with either RIBO- or deoxyribonucleic acid [ 2 PDB entries ] 
     E.C.3.1.31.- Endonucleases active with either RIBO- or deoxyribonucleic acid [ 33 PDB entries ]


E.C.3.2.-.- Glycosidases.

There are 599 PDB entries in enzyme class E.C.3.2.-.- 

     E.C.3.2.1.- Hydrolysing O-glycosyl compounds. [ 570 PDB entries ] 
     E.C.3.2.2.- Hydrolysing N-glycosyl compounds. [ 27 PDB entries ] 
     E.C.3.2.3.- Hydrolysing S-glycosyl compounds. [ 2 PDB entries ] 


E.C.3.3.-.- Acting on ether bonds.

There are no PDB entries in enzyme class E.C.3.3.-.- 

     E.C.3.3.1.- Thioether hydrolases. [-] 
     E.C.3.3.2.- Ether hydrolases. [-] 


E.C.3.4.-.- Acting on peptide bonds (peptide hydrolases).

There are 756 PDB entries in enzyme class E.C.3.4.-.- 

     E.C.3.4.11.- Aminopeptidases. [ 17 PDB entries ] 
     E.C.3.4.13.- Dipeptidases. [-] 
     E.C.3.4.14.- Dipeptidyl-peptidases and tripeptidyl-peptidases. [-] 
     E.C.3.4.15.- Peptidyl-dipeptidases. [-] 
     E.C.3.4.16.- Serine-type carboxypeptidases. [ 13 PDB entries ] 
     E.C.3.4.17.- Metallocarboxypeptidases. [ 21 PDB entries ] 
     E.C.3.4.18.- Cysteine-type carboxypeptidases. [-] 
     E.C.3.4.19.- Omega peptidases. [-] 
     E.C.3.4.21.- Serine endopeptidases. [ 371 PDB entries ] 
     E.C.3.4.22.- Cysteine endopeptidases. [ 72 PDB entries ] 
     E.C.3.4.23.- Aspartic endopeptidases. [ 195 PDB entries ] 
     E.C.3.4.24.- Metalloendopeptidases. [ 64 PDB entries ] 
     E.C.3.4.99.- Endopeptidases of unknown catalytic mechanism. [ 3 PDB entries ] 


E.C.3.5.-.- Acting on carbon-nitrogen bonds, other than peptide bonds.

There are 79 PDB entries in enzyme class E.C.3.5.-.- 

     E.C.3.5.1.- In linear amides. [ 40 PDB entries ] 
     E.C.3.5.2.- In cyclic amides. [ 25 PDB entries ] 
     E.C.3.5.3.- In linear amidines. [ 2 PDB entries ] 
     E.C.3.5.4.- In cyclic amidines. [ 12 PDB entries ] 
     E.C.3.5.5.- In nitriles. [-] 
     E.C.3.5.99.- In other compounds. [-] 


E.C.3.6.-.- Acting on acid anhydrides.

There are 56 PDB entries in enzyme class E.C.3.6.-.- 

     E.C.3.6.1.- In phosphorous-containing anhydrides. [ 56 PDB entries ] 
     E.C.3.6.2.- In sulfonyl-containing anhydrides. [-] 


E.C.3.7.-.- Acting on carbon-carbon bonds.

There are no PDB entries in enzyme class E.C.3.7.-.- 

     E.C.3.7.1.- In ketonic substances. [-] 


E.C.3.8.-.- Acting on halide bonds.

There are 13 PDB entries in enzyme class E.C.3.8.-.- 

     E.C.3.8.1.- In C-halide compounds. [ 13 PDB entries ] 
     E.C.3.8.2.- (not defined) [-] 


E.C.3.9.-.- Acting on phosphorus-nitrogen bonds.

There are no PDB entries in enzyme class E.C.3.9.-.- 

     E.C.3.9.1.- (not defined) [-] 


E.C.3.10.-.- Acting on sulfur-nitrogen bonds.

There are no PDB entries in enzyme class E.C.3.10.-.- 

     E.C.3.10.1.- (not defined) [-] 


E.C.3.11.-.- Acting on carbon-phosphorus bonds.

There are no PDB entries in enzyme class E.C.3.11.-.- 

     E.C.3.11.1.- (not defined) [-] 


E.C.3.12.-.- Acting on sulfur-sulfur bonds.

There are no PDB entries in enzyme class E.C.3.12.-.- 

     E.C.3.12.1.- (not defined) [-] 


E.C.4.-.-.- Lyases.

The lyases are enzymes cleaving C-C, C-O, C-N, and other bonds by elimination, leaving double bonds
or rings, or conversely adding groups to double bonds. 

There are 247 PDB entries in enzyme class E.C.4.-.-.- 

E.C.4.1.-.- Carbon-carbon lyases.

There are 71 PDB entries in enzyme class E.C.4.1.-.- 

     E.C.4.1.1.- Carboxy-lyases. [ 34 PDB entries ] 
     E.C.4.1.2.- Aldehyde-lyases. [ 10 PDB entries ] 
     E.C.4.1.3.- OXO-ACID-Lyases. [ 22 PDB entries ] 
     E.C.4.1.99.- Other carbon-carbon lyases. [ 5 PDB entries ] 


E.C.4.2.-.- Carbon-oxygen lyases.

There are 163 PDB entries in enzyme class E.C.4.2.-.- 

     E.C.4.2.1.- HYDRO-Lyases. [ 153 PDB entries ] 
     E.C.4.2.2.- Acting on polysaccharides. [ 6 PDB entries ] 
     E.C.4.2.99.- Other carbon-oxygen lyases. [ 4 PDB entries ] 


E.C.4.3.-.- Carbon-nitrogen lyases.

There are 4 PDB entries in enzyme class E.C.4.3.-.- 

     E.C.4.3.1.- Ammonia-lyases. [ 3 PDB entries ] 
     E.C.4.3.2.- Amidine-lyases. [ 1 PDB entry ] 
     E.C.4.3.3.- AMINE-Lyases. [-] 
     E.C.4.3.99.- Other carbon-nitrogen-lyases. [-] 


E.C.4.4.-.- Carbon-sulfur lyases.

There is 1 PDB entry in enzyme class E.C.4.4.-.- 

     E.C.4.4.1.- (not defined) [ 1 PDB entry ] 


E.C.4.5.-.- Carbon-halide lyases.

There are no PDB entries in enzyme class E.C.4.5.-.- 

     E.C.4.5.1.- (not defined) [-] 


E.C.4.6.-.- Phosphorus-oxygen lyases.

There are 6 PDB entries in enzyme class E.C.4.6.-.- 

     E.C.4.6.1.- (not defined) [ 6 PDB entries ] 


E.C.4.99.-.- Other lyases.

There are 2 PDB entries in enzyme class E.C.4.99.-.- 

     E.C.4.99.1.- (not defined) [ 2 PDB entries ] 


E.C.5.-.-.- Isomerases.


The isomerases catalyse geometric or structural changes within one molecule. 

According to the type of isomerism, they may be called racemases, epimerases, cis-tran-isomerases,
isomerases, tautomerases, mutases or cylcoisomerases. 

The subclasses are defined according to the type of isomerism, the sub-subclasses to the type of
substrates. 

There are 186 PDB entries in enzyme class E.C.5.-.-.- 

E.C.5.1.-.- Racemases and epimerases.

There are 14 PDB entries in enzyme class E.C.5.1.-.- 

     E.C.5.1.1.- Acting on amino acids and derivatives. [ 1 PDB entry ] 
     E.C.5.1.2.- Acting on hydroxy acids and derivatives. [ 6 PDB entries ] 
     E.C.5.1.3.- Acting on carbohydrates and derivatives. [ 7 PDB entries ] 
     E.C.5.1.99.- Acting on other compounds. [-] 


E.C.5.2.-.- CIS-TRANS-Isomerases.

There are 42 PDB entries in enzyme class E.C.5.2.-.- 

     E.C.5.2.1.- (not defined) [ 42 PDB entries ] 


E.C.5.3.-.- Intramolecular oxidoreductases.

There are 103 PDB entries in enzyme class E.C.5.3.-.- 

     E.C.5.3.1.- Interconverting aldoses and ketoses. [ 100 PDB entries ] 
     E.C.5.3.2.- Interconverting KETO- and ENOL- groups. [-] 
     E.C.5.3.3.- Transposing C==C groups. [ 2 PDB entries ] 
     E.C.5.3.4.- Transposing S-S bonds. [ 1 PDB entry ] 
     E.C.5.3.99.- Other intramolecular oxidoreductases. [-] 


E.C.5.4.-.- Intramolecular transferases (mutases).

There are 18 PDB entries in enzyme class E.C.5.4.-.- 

     E.C.5.4.1.- Transferring acyl groups. [-] 
     E.C.5.4.2.- Phosphotransferases (phosphomutases). [ 7 PDB entries ] 
     E.C.5.4.3.- Transferring amino groups. [-] 
     E.C.5.4.99.- Transferring other groups. [ 11 PDB entries ] 


E.C.5.5.-.- Intramolecular lyases.

There are 4 PDB entries in enzyme class E.C.5.5.-.- 

     E.C.5.5.1.- (not defined) [ 4 PDB entries ] 


E.C.5.99.-.- Other isomerases.

There are 5 PDB entries in enzyme class E.C.5.99.-.- 

     E.C.5.99.1.- (not defined) [ 5 PDB entries ] 


E.C.6.-.-.- Ligases.

The ligases catalyse the joining together of two molecules coupled with the hydrolysis of a pyrophosphate
bond in ATP or a similar triphosphate. The bonds formed are often high-energy bonds. 

The subclasses are defined according to the type of bond formed; the sub-subclasses are only used in the
C-N ligases. 

There are 76 PDB entries in enzyme class E.C.6.-.-.- 


E.C.6.1.-.- Forming carbon-oxygen bonds.

There are 32 PDB entries in enzyme class E.C.6.1.-.- 

     E.C.6.1.1.- Ligases forming aminoacyl-trna and related compounds. [ 32 PDB entries ] 


E.C.6.2.-.- Forming carbon-sulfur bonds.

There is 1 PDB entry in enzyme class E.C.6.2.-.- 

     E.C.6.2.1.- ACID--Thiol ligases. [ 1 PDB entry ] 


E.C.6.3.-.- Forming carbon-nitrogen bonds.

There are 41 PDB entries in enzyme class E.C.6.3.-.- 

     E.C.6.3.1.- ACID--Ammonia (OR AMINE) ligases (amide synthases). [ 3 PDB entries ] 
     E.C.6.3.2.- ACID--AMINO-Acid ligases (peptide synthases). [ 13 PDB entries ] 
     E.C.6.3.3.- CYCLO-Ligases. [ 8 PDB entries ] 
     E.C.6.3.4.- Other carbon--nitrogen ligases. [ 15 PDB entries ] 
     E.C.6.3.5.- Carbon--nitrogen ligases with glutamine as AMIDO-N-donor. [ 2 PDB entries ] 


E.C.6.4.-.- Forming carbon-carbon bonds.

There are 2 PDB entries in enzyme class E.C.6.4.-.- 

     E.C.6.4.1.- (not defined) [ 2 PDB entries ] 


E.C.6.5.-.- Forming phosphoric ester bonds.

There are no PDB entries in enzyme class E.C.6.5.-.- 

     E.C.6.5.1.- (not defined) [-]