5.3.1.9 4.1.2.13 5.3.1.1 1.2.1.12 2.7.2.3 5.4.2.1 4.2.1.11 1.1.1.49 1.1.1.44 5.1.3.1 5.3.1.6 2.2.1.1 4.1.3.7 4.2.1.3 1.1.1.42 1.3.9.91 4.2.1.2 1.1.1.37 Pathway View

ENZYME: 5.3.1.6 5.3.1.6 FLUX VALUES Flux variation (Standard deviation):8.681 Flux BSUB ECOL HPYL HINF SCER Normal 11.34 26 10 10 2.15 Absolute 0.1 2.77 10 10 2.15 Seq ID bsuywlF ecob2914 hpyHP0574 hinHI0464 sceYOR095C PERCENTAGE IDENTITY Average PID: 0.548 % ID BSUB ECOL HPYL HINF SCER BSUB 1.000 0.321 0.408 0.346 0.429 ECOL 0.321 1.000 0.364 0.651 0.316 HPYL 0.408 0.346 1.000 0.389 0.333 HINF 0.346 0.651 0.316 1.000 0.319 SCER 0.429 0.316 0.333 0.319 1.000 EXPRESSION DATA Multi-scale Reference: 3.6 copies per cell Standard Deviation of Expression Change Experiment cellcycle_cdc15 cellcycle_alpha diaux yeast_sporu ecoli_UV worm average STDEV 0.356 0.250 0.719 0.194 0.216 0.401 0.356 Average of Expression Change Experiment cellcycle_cdc15 cellcycle_alpha diaux yeast_sporu ecoli_UV worm average stdev STDEV -0.105 -0.009 -0.379 0.157 0.170 0.312 0.024 0.246 EXPRESSION TIMEPOINTS Mitotic Cell Cycle [normalized transcript level divided by mean value] link 0 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 314 599 494 532 552 466 440 579 563 523 559 468 608 666 686 582 718 Alpha Factor Arrest Synchronization [log2(ratio of mRNA levels)] link 0 7 14 21 28 35 42 49 56 63 70 77 84 91 98 105 112 119 -0.44 -0.46 -0.34 -0.03 -0.08 -0.11 0.62 0.27 -0.09 0.33 -0.14 0.09 -0.05 0.2 -0.06 -0.06 -0.09 0.55 CDC15 Synchronization [log2(ratio of mRNA levels)] link 10 30 50 70 80 90 100 110 120 130 140 150 160 0.55 0.35 0.2 -0.21 0.23 -0.04 0.34 -0.17 0.35 -0.27 0.2 -0.66 -0.1 170 180 190 200 210 220 230 240 250 270 290 -0.37 0.22 0.07 0.22 0.19 -0.57 -0.57 0 -0.21 -0.31 -0.76 CDC28 (Stanford) [log2(ratio of mRNA levels)] 0 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 0.17 -0.11 0 0.05 -0.19 -0.28 0.12 0.08 -0.03 0.07 -0.19 0.19 0.32 N/A 0.13 0.43 -1.29 Elutration Synchronization [log2(ratio of mRNA levels)] link 0 30 60 90 120 150 180 210 240 270 300 330 360 390 -0.18 0.24 0.62 0.58 0.22 0.33 -0.01 -0.13 0.05 0.651 -0.19 0.19 0.32 N/A