5.3.1.9 4.1.2.13 5.3.1.1 1.2.1.12 2.7.2.3 5.4.2.1 4.2.1.11 1.1.1.49 1.1.1.44 5.1.3.1 5.3.1.6 2.2.1.1 4.1.3.7 4.2.1.3 1.1.1.42 1.3.9.91 4.2.1.2 1.1.1.37 Pathway View

ENZYME: 5.3.1.1 5.3.1.1 FLUX VALUES Flux variation (Standard deviation):13.867 Flux BSUB ECOL HPYL HINF SCER Normal 81 45 0 70 76 Absolute 0.81 4.68 0 70 76.36 Seq ID bsutpi ecob3919 hpyHP0194 hinHI0678 sceYDR050C PERCENTAGE IDENTITY Average PID: 0.608 % ID BSUB ECOL HPYL HINF SCER BSUB 1.000 0.394 0.344 0.42 0.429 ECOL 0.394 1.000 0.351 0.727 0.455 HPYL 0.344 0.42 1.000 0.37 0.332 HINF 0.42 0.727 0.455 1.000 0.44 SCER 0.429 0.455 0.332 0.44 1.000 EXPRESSION DATA Multi-scale Reference: 57.54941665 copies per cell Standard Deviation of Expression Change Experiment cellcycle_cdc15 cellcycle_alpha diaux yeast_sporu ecoli_UV worm average STDEV 0.547 0.209 0.314 0.162 0.562 1.423 0.536 Average of Expression Change Experiment cellcycle_cdc15 cellcycle_alpha diaux yeast_sporu ecoli_UV worm average stdev STDEV 0.060 0.138 0.090 -0.122 0.632 0.000 0.133 0.260 EXPRESSION TIMEPOINTS Mitotic Cell Cycle [normalized transcript level divided by mean value] link 0 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 2113 2027 2566 2320 2700 1719 2410 2174 1791 6731 3647 3128 1948 3788 3979 3673 3991 Alpha Factor Arrest Synchronization [log2(ratio of mRNA levels)] link 0 7 14 21 28 35 42 49 56 63 70 77 84 91 98 105 112 119 -0.16 -0.11 -0.1 -0.06 -0.26 -0.03 -0.31 -0.13 0.29 0.27 0.41 -0.26 0.09 -0.22 0.14 0.29 -0.01 0.14 CDC15 Synchronization [log2(ratio of mRNA levels)] link 10 30 50 70 80 90 100 110 120 130 140 150 160 -1.16 -1.3 -1.09 -0.09 0.05 0.51 0.55 0.44 0.25 0.33 -0.12 0.33 -0.03 170 180 190 200 210 220 230 240 250 270 290 0.24 0.34 0.55 0.19 0.7 0.1 -0.14 -0.47 0.09 -0.17 -0.09 CDC28 (Stanford) [log2(ratio of mRNA levels)] 0 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 -0.39 -0.45 -0.11 -0.25 -0.03 -0.69 -0.2 -0.35 -0.63 1.28 0.4 N/A -0.51 0.45 0.52 0.41 0.53 Elutration Synchronization [log2(ratio of mRNA levels)] link 0 30 60 90 120 150 180 210 240 270 300 330 360 390 -0.21 -0.22 0.1 0.21 -0.43 -0.18 -0.5 0.14 0.02 0.727 0.4 N/A -0.51 0.45