5.3.1.9 4.1.2.13 5.3.1.1 1.2.1.12 2.7.2.3 5.4.2.1 4.2.1.11 1.1.1.49 1.1.1.44 5.1.3.1 5.3.1.6 2.2.1.1 4.1.3.7 4.2.1.3 1.1.1.42 1.3.9.91 4.2.1.2 1.1.1.37 Pathway View

ENZYME: 2.2.1.1 2.2.1.1 FLUX VALUES Flux variation (Standard deviation):6.984 Flux BSUB ECOL HPYL HINF SCER Normal 17 15 20 20 3.12 Absolute 0.17 1.59 20 20 3.12 Seq ID bsutkt ecob2935 hpyHP1088 hinHI1023 sceYPR074C PERCENTAGE IDENTITY Average PID: 0.650 % ID BSUB ECOL HPYL HINF SCER BSUB 1.000 0.492 0.464 0.506 0.484 ECOL 0.492 1.000 0.403 0.773 0.472 HPYL 0.464 0.506 1.000 0.423 0.425 HINF 0.506 0.773 0.472 1.000 0.492 SCER 0.484 0.472 0.425 0.492 1.000 EXPRESSION DATA Multi-scale Reference: 11.34845153 copies per cell Standard Deviation of Expression Change Experiment cellcycle_cdc15 cellcycle_alpha diaux yeast_sporu ecoli_UV worm average STDEV 1.292 0.187 0.841 0.263 0.302 0.631 0.586 Average of Expression Change Experiment cellcycle_cdc15 cellcycle_alpha diaux yeast_sporu ecoli_UV worm average stdev STDEV -0.073 0.043 0.398 -0.104 0.252 0.810 0.221 0.347 EXPRESSION TIMEPOINTS Mitotic Cell Cycle [normalized transcript level divided by mean value] link 0 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 936 854 1139 1103 1482 1171 1132 1179 1240 2519 1718 1225 1148 1609 1477 1368 1739 Alpha Factor Arrest Synchronization [log2(ratio of mRNA levels)] link 0 7 14 21 28 35 42 49 56 63 70 77 84 91 98 105 112 119 0.17 -0.3 -0.13 0.15 -0.08 0.13 0.15 -0.04 0.18 -0.19 0.2 -0.16 -0.13 -0.19 0.18 0.02 0.18 -0.16 CDC15 Synchronization [log2(ratio of mRNA levels)] link 10 30 50 70 80 90 100 110 120 130 140 150 160 -0.13 -0.36 -0.36 0.13 0.66 0.32 0.8 0.23 0.73 0.06 0 -0.08 0.13 170 180 190 200 210 220 230 240 250 270 290 -0.34 0.06 -0.12 0.46 -0.1 0.38 -0.91 0.22 -0.5 -0.67 -0.62 CDC28 (Stanford) [log2(ratio of mRNA levels)] 0 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 -0.5 -0.63 -0.21 -0.26 0.17 -0.17 -0.22 -0.16 -0.09 0.93 0.38 -0.11 N/A 0.28 0.16 0.05 0.4 Elutration Synchronization [log2(ratio of mRNA levels)] link 0 30 60 90 120 150 180 210 240 270 300 330 360 390 -1.95 -0.89 -0.14 0.56 0.67 0.33 0.32 0.53 0.34 0.773 0.38 -0.11 N/A 0.28