5.3.1.9 4.1.2.13 5.3.1.1 1.2.1.12 2.7.2.3 5.4.2.1 4.2.1.11 1.1.1.49 1.1.1.44 5.1.3.1 5.3.1.6 2.2.1.1 4.1.3.7 4.2.1.3 1.1.1.42 1.3.9.91 4.2.1.2 1.1.1.37 Pathway View

ENZYME: 1.2.1.12 1.2.1.12 FLUX VALUES Flux variation (Standard deviation):15.143 Flux BSUB ECOL HPYL HINF SCER Normal 168 150 70 140 171.7 Absolute 1.68 15.7 70 140 171.74 Seq ID bsugapB ecob1779 hpyHP0921 hinHI0001 sceYGR192C PERCENTAGE IDENTITY Average PID: 0.705 % ID BSUB ECOL HPYL HINF SCER BSUB 1.000 0.503 0.415 0.479 0.486 ECOL 0.503 1.000 0.4 0.832 0.683 HPYL 0.415 0.479 1.000 0.398 0.402 HINF 0.479 0.832 0.683 1.000 0.659 SCER 0.486 0.683 0.402 0.659 1.000 EXPRESSION DATA Multi-scale Reference: 3.6 copies per cell Standard Deviation of Expression Change Experiment cellcycle_cdc15 cellcycle_alpha diaux yeast_sporu ecoli_UV worm average STDEV 0.730 0.231 0.228 0.427 0.336 0.866 0.470 Average of Expression Change Experiment cellcycle_cdc15 cellcycle_alpha diaux yeast_sporu ecoli_UV worm average stdev STDEV -0.075 0.357 0.242 -0.258 0.453 0.918 0.273 0.415 EXPRESSION TIMEPOINTS Mitotic Cell Cycle [normalized transcript level divided by mean value] link 0 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 622 545 515 450 277 237 220 201 198 314 371 391 337 317 382 389 422 Alpha Factor Arrest Synchronization [log2(ratio of mRNA levels)] link 0 7 14 21 28 35 42 49 56 63 70 77 84 91 98 105 112 119 0.11 -0.46 0.25 0.04 0.31 0.17 0.51 0.23 0.11 0.04 -0.07 -0.45 0.1 -0.38 0.2 -0.35 -0.08 -0.27 CDC15 Synchronization [log2(ratio of mRNA levels)] link 10 30 50 70 80 90 100 110 120 130 140 150 160 -0.84 -1.37 -1.4 -0.54 -0.52 0.04 0.14 0.22 0.67 0.21 0.17 0.24 0.13 170 180 190 200 210 220 230 240 250 270 290 -0.01 0.08 0.39 0.47 0.68 0.99 -0.7 -0.17 0.39 0.38 0.34 CDC28 (Stanford) [log2(ratio of mRNA levels)] 0 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 0.84 0.65 0.57 0.38 -0.32 -0.55 -0.66 -0.79 -0.81 -0.14 0.1 0.17 -0.04 N/A 0.14 0.17 0.28 Elutration Synchronization [log2(ratio of mRNA levels)] link 0 30 60 90 120 150 180 210 240 270 300 330 360 390 0.81 0.17 0.6 0.16 -0.01 -0.36 -0.83 -0.31 -0.07 0.832 0.1 0.17 -0.04 N/A