5.3.1.9 4.1.2.13 5.3.1.1 1.2.1.12 2.7.2.3 5.4.2.1 4.2.1.11 1.1.1.49 1.1.1.44 5.1.3.1 5.3.1.6 2.2.1.1 4.1.3.7 4.2.1.3 1.1.1.42 1.3.9.91 4.2.1.2 1.1.1.37 Pathway View

ENZYME: 1.1.1.49 1.1.1.49 FLUX VALUES Flux variation (Standard deviation):15.941 Flux BSUB ECOL HPYL HINF SCER Normal 34 51 100 30 6.34 Absolute 0.34 5.33 100 30 6.34 Seq ID bsuyqjJ ecob1852 hpyHP1101 hinHI0558 sceYNL241C PERCENTAGE IDENTITY Average PID: 0.540 % ID BSUB ECOL HPYL HINF SCER BSUB 1.000 0.396 0.338 0.412 0.382 ECOL 0.396 1.000 0.339 0.437 0.347 HPYL 0.338 0.412 1.000 0.316 0.311 HINF 0.412 0.437 0.347 1.000 0.343 SCER 0.382 0.347 0.311 0.343 1.000 EXPRESSION DATA Multi-scale Reference: 2.481851645 copies per cell Standard Deviation of Expression Change Experiment cellcycle_cdc15 cellcycle_alpha diaux yeast_sporu ecoli_UV worm average STDEV 0.441 0.276 0.243 0.599 0.378 0.370 0.385 Average of Expression Change Experiment cellcycle_cdc15 cellcycle_alpha diaux yeast_sporu ecoli_UV worm average stdev STDEV -0.158 0.264 -0.015 -0.717 0.343 0.507 0.037 0.442 EXPRESSION TIMEPOINTS Mitotic Cell Cycle [normalized transcript level divided by mean value] link 0 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 479 341 234 421 697 558 470 356 393 571 553 615 516 393 408 563 432 Alpha Factor Arrest Synchronization [log2(ratio of mRNA levels)] link 0 7 14 21 28 35 42 49 56 63 70 77 84 91 98 105 112 119 0.21 0.26 0.72 -0.15 0.02 -0.16 0.37 -0.07 -0.02 0.02 -0.16 0.07 -0.16 -0.59 -0.3 -0.11 -0.08 0.14 CDC15 Synchronization [log2(ratio of mRNA levels)] link 10 30 50 70 80 90 100 110 120 130 140 150 160 -0.33 -1.35 -1.01 -0.02 0.15 -0.19 -0.33 -0.43 -0.11 0.18 0.04 0.28 0.33 170 180 190 200 210 220 230 240 250 270 290 0.32 0.31 -0.08 -0.13 0.06 -0.13 -0.02 0.74 0.63 0.55 0.52 CDC28 (Stanford) [log2(ratio of mRNA levels)] 0 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 0.06 -0.43 -0.98 -0.13 0.6 0.28 0.03 -0.37 -0.23 0.31 0.26 0.42 0.16 N/A -0.17 0.29 -0.09 Elutration Synchronization [log2(ratio of mRNA levels)] link 0 30 60 90 120 150 180 210 240 270 300 330 360 390 0.04 -0.04 -0.13 -0.07 -0.01 0.08 0.04 0.1 0.17 0.437 0.26 0.42 0.16 N/A