Abstract: We survey methods used in determining protein abundance levels (divided into 2D-electrophoresis and mass-spectrometry based methods) and recent attempts to correlate protein abundance and mRNA expression. We discuss the results of these comparisons, focusing on yeast. In the process we merge together much of the available yeast protein abundance data, and use this larger data set to find correlations between protein and mRNA expression data both globally, and in terms of smaller categories of proteins. (TEXT) (Supplemental information is available at http://bioinfo.mbb.yale.edu/expression/prot-v-mrna/ |
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